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6OPF
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BU of 6opf by Molmil
Crystal structure of dmNxf2 UBA domain fused with Panoramix helix
Descriptor: Nuclear RNA export factor 2, Panoramix fusion
Authors:Wang, J, Patel, D.J.
Deposit date:2019-04-24
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat.Struct.Mol.Biol., 26, 2019
8JE4
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BU of 8je4 by Molmil
Crystal structure of LimF prenyltransferase (H239G/W273T mutant) bound with the thiodiphosphate moiety of farnesyl S-thiolodiphosphate (FSPP)
Descriptor: MAGNESIUM ION, TRIHYDROGEN THIODIPHOSPHATE, prenyltransferase, ...
Authors:Hamada, K, Oguni, A, Zhang, Y, Satake, M, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
Deposit date:2023-05-15
Release date:2023-11-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Switching Prenyl Donor Specificities of Cyanobactin Prenyltransferases.
J.Am.Chem.Soc., 145, 2023
6O9M
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BU of 6o9m by Molmil
Structure of the human apo TFIIH
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
6WTB
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BU of 6wtb by Molmil
Sort-Tagged Drosophila Cryptochrome
Descriptor: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION
Authors:Schneps, C.M, Crane, B.R.
Deposit date:2020-05-02
Release date:2021-05-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome.
Commun Biol, 4, 2021
8JLW
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BU of 8jlw by Molmil
CCHFV envelope protein Gc in complex with Gc8
Descriptor: Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain
Authors:Chong, T, Cao, S.
Deposit date:2023-06-03
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
8JKD
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BU of 8jkd by Molmil
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Descriptor: Glycoprotein C
Authors:Chong, T, Cao, S.
Deposit date:2023-06-01
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
6X38
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BU of 6x38 by Molmil
Crystal structure of the FN5 domain of Drosophila Lar
Descriptor: Tyrosine-protein phosphatase Lar, ZINC ION
Authors:Bouyain, S, Kawakami, J.E.
Deposit date:2020-05-21
Release date:2021-05-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Complex protein interactions mediate Drosophila Lar function in muscle tissue.
Plos One, 17, 2022
6XRP
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BU of 6xrp by Molmil
Crystal structure of GlpG in complex with peptide ketoamide inhibitor, Ac-RVWHA-ketoamide-phenylbutyl
Descriptor: N-(4-phenylbutyl)formamide, Rhomboid protease GlpG, peptide ketoamide inhibitor
Authors:Urban, S, Cho, S.
Deposit date:2020-07-13
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
6XTZ
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BU of 6xtz by Molmil
Structure of Dally-like protein in complex with O-palmitoleoyl serine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dally-like, ...
Authors:Vecchia, L, Jones, E.Y.
Deposit date:2020-01-16
Release date:2020-07-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
Nature, 585, 2020
6XRO
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BU of 6xro by Molmil
Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2
Descriptor: CHLORIDE ION, Rhomboid protease GlpG, SODIUM ION, ...
Authors:Urban, S, Cho, S.
Deposit date:2020-07-13
Release date:2020-09-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
2IL3
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BU of 2il3 by Molmil
Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
Descriptor: Epsilon-class Glutathione S-transferase
Authors:Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IMK
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BU of 2imk by Molmil
Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
Descriptor: Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE
Authors:Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
6OZ9
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BU of 6oz9 by Molmil
Ebola virus glycoprotein in complex with EBOV-520 Fab
Descriptor: EBOV-520 Fab heavy chain, EBOV-520 Fab light chain, Envelope glycoprotein, ...
Authors:Milligan, J.C, Altman, P.X, Hui, S, Hastie, K.M, Gilchuk, P, Crowe, J.E, Saphire, E.O.
Deposit date:2019-05-15
Release date:2020-03-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.462 Å)
Cite:Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6P50
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BU of 6p50 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ...
Authors:Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
Deposit date:2019-05-29
Release date:2019-09-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6PJU
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BU of 6pju by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6P69
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BU of 6p69 by Molmil
Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to compound 11.
Descriptor: 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide, ...
Authors:Larsen, N.A.
Deposit date:2019-06-03
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:To be published
TBD
8JHP
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BU of 8jhp by Molmil
Another hairpin structure found in the RNA element involved in piRNA biogenesis
Descriptor: RNA (27-MER)
Authors:Takase, N, Kawai, G.
Deposit date:2023-05-25
Release date:2024-05-29
Method:SOLUTION NMR
Cite:Another hairpin structure found in the RNA element involved in piRNA biogenesis
To Be Published
6PJR
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BU of 6pjr by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6XYH
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BU of 6xyh by Molmil
NMR solution structure of alpha-AnmTX-Ms11a-2 (Ms11a-2)
Descriptor: AMS3
Authors:Mineev, K.S, Kornilov, F.D, Lushpa, V.A, Logashina, Y.A, Maleeva, E.E, Andreev, Y.A.
Deposit date:2020-01-30
Release date:2021-02-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR solution structure of alpha-AnmTX-Ms11a-2 (Ms11a-2)
To Be Published
8JLX
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BU of 8jlx by Molmil
CCHFV envelope protein Gc in complex with Gc13
Descriptor: Glycoprotein C,CCHFV Gc fusion loops, Mouse antibody Gc13 heavy chain, Mouse antibody Gc13 light chain
Authors:Chong, T, Cao, S.
Deposit date:2023-06-03
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
6P91
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BU of 6p91 by Molmil
Structure of Lassa virus glycoprotein bound to Fab 18.5C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 18.5C Antibody heavy chain, ...
Authors:Saphire, E.O, Hastie, K.M.
Deposit date:2019-06-09
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization.
Cell, 178, 2019
6PJA
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BU of 6pja by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6X7H
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BU of 6x7h by Molmil
Cyanovirin-N Mutation I34Y with Dimannose bound
Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
Authors:Fromme, R, Sharma, P, Ghirlanda, G.
Deposit date:2020-05-30
Release date:2021-06-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations.
Elife, 11, 2022
6PJ5
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BU of 6pj5 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-27
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ9
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BU of 6pj9 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019

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数据于2024-10-16公开中

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