459D
 
 | | DNA MINOR-GROOVE RECOGNITION OF A TRIS-BENZIMIDAZOLE DRUG | | Descriptor: | 2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*(CBR)P*AP*TP*AP*TP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*AP*TP*GP*CP*G)-3') | | Authors: | Aymami, J, Nunn, C.M, Neidle, S. | | Deposit date: | 1999-03-10 | | Release date: | 1999-06-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand.
Nucleic Acids Res., 27, 1999
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1XN1
 | | Crystal Structure Of Lumazine Synthase From Brucella Abortus (Orthorhombic Form At 3.05 Angstroms) | | Descriptor: | 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Klinke, S, Zylberman, V, Vega, D.R, Guimaraes, B.G, Braden, B.C, Goldbaum, F.A. | | Deposit date: | 2004-10-04 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystallographic studies on Decameric Brucella spp. Lumazine Synthase: A Novel Quaternary Arrangement Evolved for a New Function?
J.Mol.Biol., 353, 2005
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2FWY
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2Y70
 | | CRYSTALLOGRAPHIC STRUCTURE OF GM23, MUTANT G89D, AN EXAMPLE OF CATALYTIC MIGRATION FROM TIM TO THIAMIN PHOSPHATE SYNTHASE. | | Descriptor: | ACETATE ION, SULFATE ION, TRIOSE-PHOSPHATE ISOMERASE | | Authors: | Saab-Rincon, G, Olvera, L, Olvera, M, Rudino-Pinera, E, Soberon, X, Morett, E. | | Deposit date: | 2011-01-27 | | Release date: | 2011-12-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Evolutionary Walk between (Beta/Alpha)(8) Barrels: Catalytic Migration from Triosephosphate Isomerase to Thiamin Phosphate Synthase.
J.Mol.Biol., 416, 2012
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3W3Y
 | | Crystal structure of Kap121p bound to Nup53p | | Descriptor: | Importin subunit beta-3, Nucleoporin NUP53 | | Authors: | Kobayashi, J, Matsuura, Y. | | Deposit date: | 2012-12-28 | | Release date: | 2013-04-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
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3W3T
 | | Crystal structure of Kap121p | | Descriptor: | Importin subunit beta-3 | | Authors: | Kobayashi, J, Matsuura, Y. | | Deposit date: | 2012-12-28 | | Release date: | 2013-04-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
J.Mol.Biol., 425, 2013
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3W3V
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2Y6Z
 | | Crystallographic structure of GM23 an example of Catalytic migration from TIM to thiamin phosphate synthase. | | Descriptor: | PYROPHOSPHATE 2-, THIAMIN PHOSPHATE, TRIOSE-PHOSPHATE ISOMERASE | | Authors: | Saab-Rincon, G, Olvera, L, Olvera, M, Rudino-Pinera, E, Soberon, X, Morett, E. | | Deposit date: | 2011-01-27 | | Release date: | 2011-12-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Evolutionary Walk between (Beta/Alpha)(8) Barrels: Catalytic Migration from Triosephosphate Isomerase to Thiamin Phosphate Synthase.
J.Mol.Biol., 416, 2012
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1TZQ
 | | Crystal structure of the equinatoxin II 8-69 double cysteine mutant | | Descriptor: | Equinatoxin II | | Authors: | Kristan, K, Podlesek, Z, Hojnik, V, Gutirrez-Aguirre, I, Guncar, G, Turk, D.A, Gonzalez-Maas, J.M, Lakey, J.H, Anderluh, G. | | Deposit date: | 2004-07-11 | | Release date: | 2004-09-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich
J.Biol.Chem., 279, 2004
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3W3U
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1K4V
 | | 1.53 A Crystal Structure of the Beta-Galactoside-alpha-1,3-galactosyltransferase in Complex with UDP | | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | | Authors: | Boix, E, Swaminathan, G.J, Zhang, Y, Natesh, R, Brew, K, Acharya, K.R. | | Deposit date: | 2001-10-09 | | Release date: | 2002-04-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus.
J.Biol.Chem., 276, 2001
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1NHN
 | | THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA | | Descriptor: | HIGH MOBILITY GROUP PROTEIN 1 | | Authors: | Read, C.M, Cary, P.D, Crane-Robinson, C, Driscoll, P.C, Carillo, M.O.M, Norman, D.G. | | Deposit date: | 1994-11-17 | | Release date: | 1995-02-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Structure of the Hmg Box and its Interaction with DNA
NUCLEIC ACIDS MOL.BIOL., 9, 1995
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1NHM
 | | THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA | | Descriptor: | HIGH MOBILITY GROUP PROTEIN 1 | | Authors: | Read, C.M, Cary, P.D, Crane-Robinson, C, Driscoll, P.C, Carillo, M.O.M, Norman, D.G. | | Deposit date: | 1994-11-17 | | Release date: | 1995-02-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Structure of the Hmg Box and its Interaction with DNA
NUCLEIC ACIDS MOL.BIOL., 9, 1995
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1NC6
 | | Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone | | Descriptor: | (2S,4R)-1-ACETYL-N-[(1S)-4-[(AMINOIMINOMETHYL)AMINO]-1-(2-BENZOTHIAZOLYLCARBONYL)BUTYL]-4-HYDROXY-2-PYRROLIDINECARBOXAMIDE, CALCIUM ION, SULFATE ION, ... | | Authors: | Costanzo, M.J, Yabut, S.C, Almond Jr, H.R, Andrade-Gordon, P, Corcoran, T.W, de Garavilla, L, Kauffman, J.A, Abraham, W.M, Recacha, R, Chattopadhyay, D, Maryanoff, B.E. | | Deposit date: | 2002-12-04 | | Release date: | 2003-09-23 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone.
J.Med.Chem., 46, 2003
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1V76
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3V7F
 | | Crystal Structure of Streptococcus pyogenes Csn2 | | Descriptor: | CALCIUM ION, Putative uncharacterized protein | | Authors: | Bae, E, Jung, D.K, Koo, Y. | | Deposit date: | 2011-12-21 | | Release date: | 2012-06-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of Streptococcus pyogenes Csn2 reveals calcium-dependent conformational changes in its tertiary and quaternary structure
Plos One, 7, 2012
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2FWZ
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2M3Z
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4BGG
 | | Crystal structure of the ACVR1 kinase in complex with LDN-213844 | | Descriptor: | 1,2-ETHANEDIOL, 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine, ACTIVIN RECEPTOR TYPE-1, ... | | Authors: | Sanvitale, C, Canning, P, Cooper, C, Wang, Y, Mohedas, A.H, Choi, S, Yu, P.B, Cuny, G.D, Nowak, R, Coutandin, D, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-03-26 | | Release date: | 2013-04-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structure-Activity Relationship of 3,5-Diaryl-2-Aminopyridine Alk2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants.
J.Med.Chem., 57, 2014
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2H55
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2L54
 | | Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A) | | Descriptor: | Double-stranded RNA-specific adenosine deaminase | | Authors: | Zhao, J, Pervushin, K, Feng, S, Droge, P. | | Deposit date: | 2010-10-24 | | Release date: | 2011-01-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Alternate rRNA secondary structures as regulators of translation
Nat.Struct.Mol.Biol., 18, 2011
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1S1Y
 | | Photoactivated chromophore conformation in Photoactive Yellow Protein (E46Q mutant) from 10 microseconds to 3 milliseconds | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | Authors: | Anderson, S, Srajer, V, Pahl, R, Rajagopal, S, Schotte, F, Anfinrud, P, Wulff, M, Moffat, K. | | Deposit date: | 2004-01-07 | | Release date: | 2004-06-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein
Structure, 12, 2004
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1S1Z
 | | Photoactivated chromophore conformation in Photoactive Yellow Protein (E46Q mutant) from 10 to 500 nanoseconds | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive Yellow Protein | | Authors: | Anderson, S, Srajer, V, Pahl, R, Rajagopal, S, Schotte, F, Anfinrud, P, Wulff, M, Moffat, K. | | Deposit date: | 2004-01-07 | | Release date: | 2004-06-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein
Structure, 12, 2004
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2JO7
 | | Solution structure of the adhesion protein Bd37 from Babesia divergens | | Descriptor: | Glycosylphosphatidylinositol-anchored merozoite surface protein | | Authors: | Auguin, D, Yang, Y, Lohr, F, Arold, S, Schetters, T, Precigout, E, Gorenflot, A, Delbecq, S, Roumestand, C. | | Deposit date: | 2007-02-26 | | Release date: | 2007-12-11 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The Solution Structure of the Adhesion Protein Bd37 from Babesia divergens Reveals Structural Homology with Eukaryotic Proteins Involved in Membrane Trafficking
J.Mol.Biol., 375, 2007
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3QAI
 | | X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 3 | | Descriptor: | Ketohexokinase, N~8~-(cyclopropylmethyl)-2-(2,6-diazaspiro[3.3]hept-2-yl)-N~4~-[2-(methylsulfanyl)phenyl]pyrimido[5,4-d]pyrimidine-4,8-diamine, SULFATE ION | | Authors: | Abad, M.C. | | Deposit date: | 2011-01-11 | | Release date: | 2012-01-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.
ACS Med Chem Lett, 2, 2011
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