PDB: 98078 resultsInfo pagesStatus searchChemie searchBIRD

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2DTH	The Crystal Structure of the Orthorhombic Form of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotin and ADP Descriptor: 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE-5'-DIPHOSPHATE, BIOTIN Authors: Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-07-12 Release date: 2007-01-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 To be Published
6U19	Solution Structure of the RAZUL domain from 26S proteasome subunit hRpn10/S5a complexed with the AZUL domain from E3 ligase E6AP/UBE3A Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin-protein ligase E3A, ZINC ION Authors: Chen, X, Walters, K.J. Deposit date: 2019-08-15 Release date: 2020-03-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10. Nat Commun, 11, 2020
3A9V	Crystal structures and enzymatic mechanisms of a Populus tomentosa 4-coumarate--CoA ligase Descriptor: 4-coumarate--CoA ligase, ADENOSINE MONOPHOSPHATE Authors: Hu, Y. Deposit date: 2009-11-06 Release date: 2010-09-08 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms Plant Cell, 22, 2010
4DWR	RNA ligase RtcB/Mn2+ complex Descriptor: MANGANESE (II) ION, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... Authors: Xia, S, Englert, M, Soll, D, Wang, J. Deposit date: 2012-02-26 Release date: 2012-09-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc.Natl.Acad.Sci.USA, 109, 2012
1A0I	ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA LIGASE Authors: Subramanya, H.S, Doherty, A.J, Ashford, S.R, Wigley, D.B. Deposit date: 1997-12-01 Release date: 1998-03-25 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7. Cell(Cambridge,Mass.), 85, 1996
6N67	Crystal structure of the ligase domain of fungal tRNA ligase Trl1 Descriptor: CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ... Authors: Peschek, J, Walter, P. Deposit date: 2018-11-26 Release date: 2019-07-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. Elife, 8, 2019
8QFC	UFL1 E3 ligase bound 60S ribosome Descriptor: 60S ribosomal protein L10a, CDK5 regulatory subunit-associated protein 3, DDRGK domain-containing protein 1, ... Authors: Makhlouf, L, Zeqiraj, E, Kulathu, Y. Deposit date: 2023-09-04 Release date: 2024-02-21 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
4DWQ	RNA ligase RtcB-GMP/Mn(2+) complex Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MALONATE ION, ... Authors: Okada, C, Xia, S, Englert, M, Yao, M, Soll, D, Wang, J. Deposit date: 2012-02-26 Release date: 2012-09-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc.Natl.Acad.Sci.USA, 109, 2012
8ENI	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor Descriptor: 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA Authors: Wilce, M.C.J, Cini, D.A. Deposit date: 2022-09-30 Release date: 2022-11-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus. ACS Infect Dis, 4, 2018
6VT4	Naegleria gruberi RNA ligase R149A mutant apo Descriptor: RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VTE	Naegleria gruberi RNA Ligase K170M mutant with AMP and Mn Descriptor: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VT8	Naegleria gruberi RNA ligase E312A mutant with AMP and Mn Descriptor: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6R7F	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. Deposit date: 2019-03-28 Release date: 2019-08-28 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (8.2 Å) Cite: Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6VT9	Naegleria gruberi RNA ligase E227A mutant with ATP and Mn Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
7LFQ	Pyrococcus RNA ligase Descriptor: DNA (5'-D(*AP*TP*GP*TP*CP*C)-3'), POTASSIUM ION, RNA-splicing ligase RtcB, ... Authors: Goldgur, Y, Shuman, S, Banerjee, A. Deposit date: 2021-01-18 Release date: 2021-03-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of 3'-PO 4 /5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide. Rna, 27, 2021
6VT0	Naegleria gruberi RNA ligase K170A mutant apo Descriptor: RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.002 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VTB	Naegleria gruberi RNA ligase K326A mutant with ATP and Mn Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.547 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
3PBK	Structural and Functional Studies of Fatty Acyl-Adenylate Ligases from E. coli and L. pneumophila Descriptor: 5'-O-[(S)-(dodecanoyloxy)(hydroxy)phosphoryl]adenosine, Fatty Acyl-Adenylate Ligase Authors: Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2010-10-20 Release date: 2010-12-22 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila. J.Mol.Biol., 406, 2011
2FYK	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in complex with ADP and Biotin Descriptor: ADENOSINE-5'-DIPHOSPHATE, BIOTIN, biotin--protein ligase Authors: Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-02-08 Release date: 2006-08-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 To be Published
6VT1	Naegleria gruberi RNA ligase D172A mutant apo Descriptor: ADENOSINE MONOPHOSPHATE, RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.381 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
5N4W	Crystal structure of the Cul2-Rbx1-EloBC-VHL ubiquitin ligase complex Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ... Authors: Cardote, T.A.F, Gadd, M.S, Ciulli, A. Deposit date: 2017-02-11 Release date: 2017-06-07 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex. Structure, 25, 2017
6VT3	Naegleria gruberi RNA ligase K326A mutant apo Descriptor: RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.844 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VTD	Naegleria gruberi RNA ligase R149A mutant with ATP and Mn Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VT5	Naegleria gruberi RNA ligase R4a K121A mutant apo Descriptor: RNA Ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020
6VTF	Naegleria gruberi RNA ligase with PPi Descriptor: PYROPHOSPHATE 2-, RNA ligase Authors: Unciuleac, M.C, Goldgur, Y, Shuman, S. Deposit date: 2020-02-12 Release date: 2020-04-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48, 2020

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