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5BST
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BU of 5bst by Molmil
Crystal structure of 4-coumarate:CoA ligase complexed with coumaroyl adenylate
Descriptor: 4-coumarate--CoA ligase 2, 5'-O-[(R)-hydroxy{[(2E)-3-(4-oxocyclohexa-1,5-dien-1-yl)prop-2-enoyl]oxy}phosphoryl]adenosine, MAGNESIUM ION
Authors:Li, Z, Nair, S.K.
Deposit date:2015-06-02
Release date:2016-05-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Basis for Specificity and Flexibility in a Plant 4-Coumarate:CoA Ligase.
Structure, 23, 2015
5BSU
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BU of 5bsu by Molmil
Crystal structure of 4-coumarate:CoA ligase complexed with caffeoyl adenylate
Descriptor: 4-coumarate--CoA ligase 2, 5'-O-[(R)-{[(2E)-3-(3,4-dioxocyclohexa-1,5-dien-1-yl)prop-2-enoyl]oxy}(hydroxy)phosphoryl]adenosine, GLYCEROL, ...
Authors:Li, Z, Nair, S.K.
Deposit date:2015-06-02
Release date:2016-05-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Specificity and Flexibility in a Plant 4-Coumarate:CoA Ligase.
Structure, 23, 2015
3W1G
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BU of 3w1g by Molmil
Crystal Structure of Human DNA ligase IV-Artemis Complex (Native)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Artemis-derived peptide, DNA ligase 4, ...
Authors:Ochi, T, Blundell, T.L.
Deposit date:2012-11-15
Release date:2013-04-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the catalytic region of DNA ligase IV in complex with an artemis fragment sheds light on double-strand break repair
Structure, 21, 2013
6N0T
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BU of 6n0t by Molmil
tRNA ligase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ...
Authors:Banerjee, A, Goldgur, Y, Shuman, S.
Deposit date:2018-11-07
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.511 Å)
Cite:Structure and two-metal mechanism of fungal tRNA ligase.
Nucleic Acids Res., 47, 2019
3R5X
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BU of 3r5x by Molmil
Crystal Structure of D-alanine--D-Alanine Ligase from Bacillus anthracis complexed with ATP
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kim, Y, Mulligan, R, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-03-20
Release date:2011-04-06
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of D-alanine--D-Alanine Ligase from Bacillus anthracis complexed with ATP
To be Published
6N0V
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BU of 6n0v by Molmil
tRNA ligase
Descriptor: MANGANESE (II) ION, tRNA ligase
Authors:Banerjee, A, Goldgur, Y, Shuman, S.
Deposit date:2018-11-07
Release date:2019-01-09
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure and two-metal mechanism of fungal tRNA ligase.
Nucleic Acids Res., 47, 2019
3W1B
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BU of 3w1b by Molmil
Crystal Structure of Human DNA ligase IV-Artemis Complex (Mercury Derivative)
Descriptor: ADENOSINE MONOPHOSPHATE, Artemis-derived peptide, DNA ligase 4, ...
Authors:Ochi, T, Blundell, T.L.
Deposit date:2012-11-14
Release date:2013-04-03
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the catalytic region of DNA ligase IV in complex with an artemis fragment sheds light on double-strand break repair
Structure, 21, 2013
3W5O
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BU of 3w5o by Molmil
Crystal Structure of Human DNA ligase IV
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA ligase 4, SULFATE ION
Authors:Gu, X, Ochi, T, Blundell, T.L.
Deposit date:2013-02-02
Release date:2013-04-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the catalytic region of DNA ligase IV in complex with an artemis fragment sheds light on double-strand break repair
Structure, 21, 2013
8IUG
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BU of 8iug by Molmil
Cryo-EM structure of the RC-LH core complex from roseiflexus castenholzii
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ...
Authors:Wang, G.-L, Qi, C.-H, Yu, L.-J.
Deposit date:2023-03-24
Release date:2023-11-22
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes.
J.Biol.Chem., 299, 2023
8IUN
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BU of 8iun by Molmil
Cryo-EM structure of the CRT-LESS RC-LH core complex from roseiflexus castenholzii
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ...
Authors:Wang, G.-L, Qi, C.-H, Yu, L.-J.
Deposit date:2023-03-24
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes.
J.Biol.Chem., 299, 2023
8IVI
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BU of 8ivi by Molmil
crystal structure of a medium-long chain fatty acyl-CoA ligase
Descriptor: Medium/long-chain-fatty-acid--CoA ligase FadD8
Authors:Li, S.
Deposit date:2023-03-27
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural study of medium-long chain fatty acyl-CoA ligase FadD8 from Mycobacterium tuberculosis.
Biochem.Biophys.Res.Commun., 672, 2023
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
Descriptor: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-09-23
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (8.3 Å)
Cite:RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
4DWQ
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BU of 4dwq by Molmil
RNA ligase RtcB-GMP/Mn(2+) complex
Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MALONATE ION, ...
Authors:Okada, C, Xia, S, Englert, M, Yao, M, Soll, D, Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DWR
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BU of 4dwr by Molmil
RNA ligase RtcB/Mn2+ complex
Descriptor: MANGANESE (II) ION, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ...
Authors:Xia, S, Englert, M, Soll, D, Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
7MO6
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BU of 7mo6 by Molmil
Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293
Descriptor: GMP synthase [glutamine-hydrolyzing]
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-05-01
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus.
Acta Crystallogr D Struct Biol, 78, 2022
8QFC
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BU of 8qfc by Molmil
UFL1 E3 ligase bound 60S ribosome
Descriptor: 60S ribosomal protein L10a, CDK5 regulatory subunit-associated protein 3, DDRGK domain-containing protein 1, ...
Authors:Makhlouf, L, Zeqiraj, E, Kulathu, Y.
Deposit date:2023-09-04
Release date:2024-02-21
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Nature, 627, 2024
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
Descriptor: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
Authors:Xu, M, Chen, S.
Deposit date:2021-04-12
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-04-19
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EL8
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BU of 7el8 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase
Descriptor: Tryptophan--tRNA ligase
Authors:Xu, M, Chen, S.
Deposit date:2021-04-09
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENT
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BU of 7ent by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-13 and ATP
Descriptor: (5S)-2-(methylamino)-5-[(1R)-1-(4-methyl-1H-indol-3-yl)ethyl]-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-04-19
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
5TT5
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BU of 5tt5 by Molmil
Escherichia coli LigA (K115M) in complex with NAD+
Descriptor: DNA ligase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Goldgur, Y, Unciuleac, M.-C, Shuman, S.H.
Deposit date:2016-11-01
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7D9K
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BU of 7d9k by Molmil
DNA binding domain of human DNA Ligase IV - Wild type
Descriptor: DNA ligase 4
Authors:Maddi, E.R, Raghavan, S.C, Natesh, R.
Deposit date:2020-10-13
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
5C7M
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BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
4EQ5
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BU of 4eq5 by Molmil
DNA ligase from the archaeon Thermococcus sibiricus
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase
Authors:Petrova, T, Bezsudnova, E.Y, Dorokhov, B.D, Slutskaya, E.S, Polyakov, K.M, Dorovatovskiy, P.V, Ravin, N.V, Skryabin, K.G, Kovalchuk, M.V, Popov, V.O.
Deposit date:2012-04-18
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Expression, purification, crystallization and preliminary crystallographic analysis of a thermostable DNA ligase from the archaeon Thermococcus sibiricus.
Acta Crystallogr.,Sect.F, 68, 2012
3GSL
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BU of 3gsl by Molmil
Crystal structure of PSD-95 tandem PDZ domains 1 and 2
Descriptor: Disks large homolog 4
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-03-27
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol., 7, 2011

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数据于2024-07-24公开中

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