6VTB
Naegleria gruberi RNA ligase K326A mutant with ATP and Mn
Summary for 6VTB
Entry DOI | 10.2210/pdb6vtb/pdb |
Descriptor | RNA ligase, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | rna repair, adenylyltransferase, ligase |
Biological source | Naegleria gruberi (Amoeba) |
Total number of polymer chains | 1 |
Total formula weight | 39275.72 |
Authors | Unciuleac, M.C.,Goldgur, Y.,Shuman, S. (deposition date: 2020-02-12, release date: 2020-04-08, Last modification date: 2023-10-11) |
Primary citation | Unciuleac, M.C.,Goldgur, Y.,Shuman, S. Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation. Nucleic Acids Res., 48:5603-5615, 2020 Cited by PubMed: 32315072DOI: 10.1093/nar/gkaa238 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.547 Å) |
Structure validation
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