8I9C
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![BU of 8i9c by Molmil](/molmil-images/mine/8i9c) | S-ECD (Omicron BF.7) in complex with PD of ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2023-02-06 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis for the enhanced infectivity and immune evasion of Omicron subvariants To Be Published
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8IAM
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![BU of 8iam by Molmil](/molmil-images/mine/8iam) | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex | Descriptor: | Chimera of Long chain base biosynthesis protein 1 and Serine palmitoyltransferase 1, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Xie, T, Gong, X. | Deposit date: | 2023-02-08 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide. Cell Rep, 43, 2024
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8I9D
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![BU of 8i9d by Molmil](/molmil-images/mine/8i9d) | S-ECD (Omicron XBB.1) in complex with PD of ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2023-02-06 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural basis for the enhanced infectivity and immune evasion of Omicron subvariants To Be Published
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8I90
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![BU of 8i90 by Molmil](/molmil-images/mine/8i90) | |
8I94
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![BU of 8i94 by Molmil](/molmil-images/mine/8i94) | Structure of flavone 4'-O-glucoside 7-O-glucosyltransferase from Nemophila menziesii, complex with luteolin | Descriptor: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Glycosyltransferase, SULFATE ION | Authors: | Murayama, K, Kato-Murayama, M, Shirouzu, M. | Deposit date: | 2023-02-06 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Molecular basis of ligand recognition specificity of flavone glucosyltransferases in Nemophila menziesii. Arch.Biochem.Biophys., 753, 2024
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8IE4
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![BU of 8ie4 by Molmil](/molmil-images/mine/8ie4) | |
8ILU
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![BU of 8ilu by Molmil](/molmil-images/mine/8ilu) | Crystal structure of mouse Galectin-3 in complex with small molecule inhibitor | Descriptor: | (2R,3R,4R,5R,6S)-2-(hydroxymethyl)-6-[2-(2-methyl-1,3-benzothiazol-6-yl)-1,2,4-triazol-3-yl]-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-3, SODIUM ION, ... | Authors: | Kumar, A, Jinal, S, Raman, S, Ghosh, K. | Deposit date: | 2023-03-04 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of Benzothiazole Derived Monosaccharides as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3 To Be Published
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7OLD
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![BU of 7old by Molmil](/molmil-images/mine/7old) | Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OLC
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![BU of 7olc by Molmil](/molmil-images/mine/7olc) | Thermophilic eukaryotic 80S ribosome at idle POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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3ZHO
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![BU of 3zho by Molmil](/molmil-images/mine/3zho) | X-ray structure of E.coli Wrba in complex with FMN at 1.2 A resolution | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVOPROTEIN WRBA | Authors: | Kishko, I, Lapkouski, M, Brynda, J, Kuty, M, Carey, J, Smatanova, I.K, Ettrich, R. | Deposit date: | 2012-12-23 | Release date: | 2013-08-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | 1.2 A Resolution Crystal Structure of Escherichia Coli Wrba Holoprotein Acta Crystallogr.,Sect.D, 69, 2013
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1GMK
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![BU of 1gmk by Molmil](/molmil-images/mine/1gmk) | GRAMICIDIN/KSCN COMPLEX | Descriptor: | GRAMICIDIN A, METHANOL, POTASSIUM ION, ... | Authors: | Doyle, D.A, Wallace, B.A. | Deposit date: | 1996-07-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the Gramicidin/Potassium Thiocyanate Complex. J.Mol.Biol., 266, 1997
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1FV0
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![BU of 1fv0 by Molmil](/molmil-images/mine/1fv0) | FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 9-HYDROXY ARISTOLOCHIC ACID, ACETATE ION, ... | Authors: | Chandra, V, Jasti, J, Kaur, P, Srinivasan, A, Betzel, C, Singh, T.P. | Deposit date: | 2000-09-18 | Release date: | 2002-08-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure Biochemistry, 41, 2002
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6MZD
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![BU of 6mzd by Molmil](/molmil-images/mine/6mzd) | Human TFIID Lobe A canonical | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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7SLR
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![BU of 7slr by Molmil](/molmil-images/mine/7slr) | HIV Reverse Transcriptase with compound Pyr01 | Descriptor: | 5-(difluoromethyl)-3-({1-[(5-fluoro-2-oxo-1,2-dihydropyridin-3-yl)methyl]-6-oxo-4-(1,1,2,2-tetrafluoroethyl)-1,6-dihydropyrimidin-5-yl}oxy)-2-methylbenzonitrile, Reverse transcriptase/ribonuclease H | Authors: | Klein, D.J, Zebisch, M, Gu, M. | Deposit date: | 2021-10-24 | Release date: | 2022-11-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.179 Å) | Cite: | Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1. Sci Transl Med, 15, 2023
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7SEI
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![BU of 7sei by Molmil](/molmil-images/mine/7sei) | Glucose-6-phosphate 1-dehydrogenase (K403Q) | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D. | Deposit date: | 2021-09-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants. J.Biol.Chem., 298, 2022
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7SC4
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![BU of 7sc4 by Molmil](/molmil-images/mine/7sc4) | filamin complex-1 | Descriptor: | Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION | Authors: | Liu, J, Qin, J. | Deposit date: | 2021-09-27 | Release date: | 2023-04-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage. Blood, 141, 2023
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7SFT
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![BU of 7sft by Molmil](/molmil-images/mine/7sft) | Filamin complex-2 | Descriptor: | Filamin-A, Integrin alpha-IIb light chain, form 2 | Authors: | Liu, J, Qin, J. | Deposit date: | 2021-10-04 | Release date: | 2023-04-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage. Blood, 141, 2023
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7SA5
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![BU of 7sa5 by Molmil](/molmil-images/mine/7sa5) | Two-state solution NMR structure of Apo Pin1 | Descriptor: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Born, A, Vogeli, B. | Deposit date: | 2021-09-22 | Release date: | 2021-10-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance. J.Am.Chem.Soc., 143, 2021
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7RY6
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![BU of 7ry6 by Molmil](/molmil-images/mine/7ry6) | Solution NMR structural bundle of the first cyclization domain from yersiniabactin synthetase (Cy1) impacted by dynamics | Descriptor: | HMWP2 nonribosomal peptide synthetase | Authors: | Kancherla, A.K, Mishra, S.H, Marincin, K.A, Nerli, S, Sgourakis, N.G, Dowling, D.P, Bouvignies, G, Frueh, D.P. | Deposit date: | 2021-08-24 | Release date: | 2022-07-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Global protein dynamics as communication sensors in peptide synthetase domains. Sci Adv, 8, 2022
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7SAW
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![BU of 7saw by Molmil](/molmil-images/mine/7saw) | Mu-conotoxin KIIIA isomer 2 | Descriptor: | Mu-conotoxin KIIIA | Authors: | Schroeder, C.I, Tran, H.N.T. | Deposit date: | 2021-09-23 | Release date: | 2022-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. J.Biol.Chem., 298, 2022
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7SJX
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![BU of 7sjx by Molmil](/molmil-images/mine/7sjx) | Cryo-EM Structure of the PR-RT components of the HIV-1 Pol Polyprotein | Descriptor: | Gag-Pol polyprotein | Authors: | Lyumkis, D, Passos, D, Arnold, E, Harrison, J.J.E.K, Ruiz, F.X. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Sci Adv, 8, 2022
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7TAA
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![BU of 7taa by Molmil](/molmil-images/mine/7taa) | FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE | Descriptor: | CALCIUM ION, MODIFIED ACARBOSE HEXASACCHARIDE, TAKA AMYLASE | Authors: | Davies, G.J, Brzozowski, A.M. | Deposit date: | 1997-10-06 | Release date: | 1998-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 A resolution. Biochemistry, 36, 1997
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7T4X
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7SY4
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![BU of 7sy4 by Molmil](/molmil-images/mine/7sy4) | Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | Deposit date: | 2021-11-24 | Release date: | 2021-12-29 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
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7SY6
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![BU of 7sy6 by Molmil](/molmil-images/mine/7sy6) | Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | Deposit date: | 2021-11-24 | Release date: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
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