3GF1
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1L5V
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![BU of 1l5v by Molmil](/molmil-images/mine/1l5v) | Crystal Structure of the Maltodextrin Phosphorylase complexed with Glucose-1-phosphate | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MALTODEXTRIN PHOSPHORYLASE, ... | Authors: | Geremia, S, Campagnolo, M, Schinzel, R, Johnson, L.N. | Deposit date: | 2002-03-08 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase J.Mol.Biol., 322, 2002
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2QSQ
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![BU of 2qsq by Molmil](/molmil-images/mine/2qsq) | Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA) | Descriptor: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 5, GLYCEROL | Authors: | Le Trong, I, Korotkova, N, Moseley, S.L, Stenkamp, R.E. | Deposit date: | 2007-07-31 | Release date: | 2008-01-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. Mol.Microbiol., 67, 2008
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3GUC
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![BU of 3guc by Molmil](/molmil-images/mine/3guc) | Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ubiquitin-like modifier-activating enzyme 5, ZINC ION | Authors: | Walker, J.R, Bacik, J.P, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-29 | Release date: | 2009-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP To be Published
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4HBU
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![BU of 4hbu by Molmil](/molmil-images/mine/4hbu) | Crystal structure of CTX-M-15 extended-spectrum beta-lactamase in complex with avibactam (NXL104) | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Docquier, J.D, Benvenuti, M, Bruneau, J.M, Rossolini, G.M, Miossec, C, Black, M.T, Mangani, S. | Deposit date: | 2012-09-28 | Release date: | 2013-04-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases Antimicrob.Agents Chemother., 57, 2013
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2VA7
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![BU of 2va7 by Molmil](/molmil-images/mine/2va7) | X-ray crystal structure of beta secretase complexed with compound 27 | Descriptor: | (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, BETA-SECRETASE 1 ., IODIDE ION | Authors: | Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L.L, Patel, S, Spear, N, Tian, G. | Deposit date: | 2007-08-30 | Release date: | 2007-11-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem., 50, 2007
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1MZ5
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![BU of 1mz5 by Molmil](/molmil-images/mine/1mz5) | Trypanosoma rangeli sialidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase | Authors: | Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M. | Deposit date: | 2002-10-05 | Release date: | 2002-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of sialyltransferase activity in trypanosomal sialidases Embo J., 19, 2000
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3HG0
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![BU of 3hg0 by Molmil](/molmil-images/mine/3hg0) | Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1 | Descriptor: | Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20 | Authors: | Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C. | Deposit date: | 2009-05-13 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J.Biol.Chem., 284, 2009
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4GRF
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![BU of 4grf by Molmil](/molmil-images/mine/4grf) | Crystal structure of thioredoxin domain of thiol-disulfide oxidoreductase BVU-2223 (Target EFI-501010) from Bacteroides vulgatus | Descriptor: | CHLORIDE ION, GLUTATHIONE, Putative thiol-disulfide oxidoreductase, ... | Authors: | Patskovsky, Y, Sampathkumar, P, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Imker, H.J, Hammonds, J, Al-Obaidi, N.F, Stead, M, Love, J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2012-08-24 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structure of thioredoxin domain of thiol-disulfide oxidoreductase BVU-2223 from Bacteroides vulgatus To be Published
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3II2
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![BU of 3ii2 by Molmil](/molmil-images/mine/3ii2) | Structure of ORF157 from Acidianus Filamentous Virus 1 | Descriptor: | CHLORIDE ION, GLYCEROL, MERCURY (II) ION, ... | Authors: | Goulet, A, Porciero, S, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | Deposit date: | 2009-07-31 | Release date: | 2010-03-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease J.Virol., 84, 2010
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3IG9
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![BU of 3ig9 by Molmil](/molmil-images/mine/3ig9) | Small outer capsid protein (SOC) of bacteriophage RB69 | Descriptor: | IMIDAZOLE, Soc small outer capsid protein | Authors: | Li, Q, Fokine, A, O'Donnell, E, Rao, V.B, Rossmann, M.G. | Deposit date: | 2009-07-27 | Release date: | 2009-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages J.Mol.Biol., 395, 2010
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2LFN
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![BU of 2lfn by Molmil](/molmil-images/mine/2lfn) | Identification of the key regions that drive functional amyloid formation by the fungal hydrophobin EAS | Descriptor: | Hydrophobin | Authors: | Macindoe, I, Kwan, A.H, Morris, V.K, Mackay, J.P, Sunde, M. | Deposit date: | 2011-07-06 | Release date: | 2012-01-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Self-assembly of functional, amphipathic amyloid monolayers by the fungal hydrophobin EAS Proc.Natl.Acad.Sci.USA, 109, 2012
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3II3
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![BU of 3ii3 by Molmil](/molmil-images/mine/3ii3) | Structure of ORF157 from Acidianus filamentous Virus 1 | Descriptor: | GLYCEROL, NICKEL (II) ION, Putative uncharacterized protein | Authors: | Goulet, A, Redder, P, Pina, M, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | Deposit date: | 2009-07-31 | Release date: | 2010-03-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease J.Virol., 84, 2010
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3ZYM
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![BU of 3zym by Molmil](/molmil-images/mine/3zym) | Structure of CALM (PICALM) in complex with VAMP8 | Descriptor: | GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ... | Authors: | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | Deposit date: | 2011-08-23 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell, 147, 2011
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2V76
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![BU of 2v76 by Molmil](/molmil-images/mine/2v76) | Crystal structure of the human dok1 PTB domain | Descriptor: | 1,2-ETHANEDIOL, DOCKING PROTEIN 1, GLYCEROL, ... | Authors: | Oxley, C.L, Anthis, N.J, Lowe, E.D, Campbell, I.D, Wegener, K.L. | Deposit date: | 2007-07-26 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding. J.Biol.Chem., 283, 2008
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4EWL
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![BU of 4ewl by Molmil](/molmil-images/mine/4ewl) | Crystal Structure of MshB with glycerol and Acetate bound in the active site | Descriptor: | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | Authors: | Broadley, S.G, Sewell, B.T, Weber, B.W, Marakalala, M.J, Steenkamp, D.J. | Deposit date: | 2012-04-27 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism. Acta Crystallogr.,Sect.D, 68, 2012
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2NPW
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![BU of 2npw by Molmil](/molmil-images/mine/2npw) | Solution Structures of a DNA Dodecamer Duplex with a Cisplatin 1,2-d(GG) Intrastrand Cross-Link | Descriptor: | 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3', Cisplatin | Authors: | Wu, Y, Bhattacharyya, D, Chaney, S, Campbell, S. | Deposit date: | 2006-10-30 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link Biochemistry, 46, 2007
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3FA2
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2VA6
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![BU of 2va6 by Molmil](/molmil-images/mine/2va6) | X-ray crystal structure of beta secretase complexed with compound 24 | Descriptor: | (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, BETA SECRETASE 1, IODIDE ION | Authors: | Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L.L, Patel, S, Spear, N, Tian, G. | Deposit date: | 2007-08-30 | Release date: | 2007-11-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem., 50, 2007
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2PNI
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![BU of 2pni by Molmil](/molmil-images/mine/2pni) | SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE SH3 DOMAIN OF THE P85ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE | Descriptor: | PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN | Authors: | Booker, G.W, Gout, I, Downing, A.K, Driscoll, P.C, Boyd, J, Waterfield, M.D, Campbell, I.D. | Deposit date: | 1993-07-19 | Release date: | 1993-10-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase. Cell(Cambridge,Mass.), 73, 1993
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2NAV
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![BU of 2nav by Molmil](/molmil-images/mine/2nav) | NMR solution structure of Ex-4[1-16]/pl14a | Descriptor: | Exendin-4, Alpha/kappa-conotoxin pl14a chimera | Authors: | Schroeder, C.I, Swedberg, J.E, Craik, D.J. | Deposit date: | 2016-01-11 | Release date: | 2016-05-04 | Last modified: | 2016-08-17 | Method: | SOLUTION NMR | Cite: | Truncated Glucagon-like Peptide-1 and Exendin-4 alpha-Conotoxin pl14a Peptide Chimeras Maintain Potency and alpha-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro. J.Biol.Chem., 291, 2016
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1OAH
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![BU of 1oah by Molmil](/molmil-images/mine/1oah) | Cytochrome c Nitrite Reductase from Desulfovibrio desulfuricans ATCC 27774: The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA). | Descriptor: | CALCIUM ION, CHLORIDE ION, CYTOCHROME C NITRITE REDUCTASE, ... | Authors: | Cunha, C.A, Macieira, S, Dias, J.M, Almeida, G, Goncalves, L.L, Costa, C, Lampreia, J, Huber, R, Moura, J.J.G, Moura, I, Romao, M.J. | Deposit date: | 2003-01-14 | Release date: | 2003-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cytochrome C Nitrite Reductase from Desulfovibrio Desulfuricans Atcc 27774. The Relevance of the Two Calcium Sites in the Structure of the Catalytic Subunit (Nrfa) J.Biol.Chem., 278, 2003
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3G9W
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![BU of 3g9w by Molmil](/molmil-images/mine/3g9w) | Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | Authors: | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | Deposit date: | 2009-02-15 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.165 Å) | Cite: | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo J., 28, 2009
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2NAW
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1NYG
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![BU of 1nyg by Molmil](/molmil-images/mine/1nyg) | |