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8AIG
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BU of 8aig by Molmil
NMR structure of holo-acp
Descriptor: 4'-PHOSPHOPANTETHEINE, Hybrid non ribosomal peptide synthetase-polyketide synthase
Authors:Collin, S, Weissman, K.J, Chagot, B, Gruez, A.
Deposit date:2022-07-26
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:Decrypting the programming of beta-methylation in virginiamycin M biosynthesis.
Nat Commun, 14, 2023
8ALL
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BU of 8all by Molmil
NMR structure of holo-acp
Descriptor: 4'-PHOSPHOPANTETHEINE, Hybrid non ribosomal peptide synthetase-polyketide synthase
Authors:Collin, S, Weissman, K.J, Chagot, B, Gruez, A.
Deposit date:2022-08-01
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:Decrypting the programming of beta-methylation in virginiamycin M biosynthesis.
Nat Commun, 14, 2023
6RSG
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BU of 6rsg by Molmil
NMR structure of pleurocidin VA in SDS micelles
Descriptor: Pleurocidin
Authors:Manzo, G, Mason, A.J.
Deposit date:2019-05-21
Release date:2020-12-09
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy.
Commun Biol, 3, 2020
6OBK
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BU of 6obk by Molmil
NMR structure of Orf47 from Lactococcus virus P2
Descriptor: Uncharacterized protein ORF47
Authors:Gagne, S.M.
Deposit date:2019-03-21
Release date:2020-04-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure determination of ORF47 from Lactococcus virus P2
To Be Published
6OWR
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BU of 6owr by Molmil
NMR solution structure of YfiD
Descriptor: Autonomous glycyl radical cofactor
Authors:Bowman, S.E.J, Drennan, C.L.
Deposit date:2019-05-10
Release date:2019-07-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme.
J.Biol.Inorg.Chem., 24, 2019
5UG5
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BU of 5ug5 by Molmil
NMR SOLUTION STRUCTURE OF THE ALPHA-CONOTOXIN GID MUTANT V13Y
Descriptor: Alpha-conotoxin GID
Authors:Hussein, A, Leffler, A.E, Kuryatov, A, Zebroski, H.A, Powell, S.R, Filipenko, P, Gorson, J, Heizmann, A, Lyskov, S, Nicke, A, Lindstrom, J, Rudy, B, Bonneau, R, Holford, M, Poget, S.F.
Deposit date:2017-01-06
Release date:2017-09-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TCZ
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BU of 5tcz by Molmil
NMR solution structure of engineered Protoxin-II analog
Descriptor: Beta/omega-theraphotoxin-Tp2a
Authors:Gibbs, A.C, Wickenden, A.D.
Deposit date:2016-09-16
Release date:2017-01-18
Method:SOLUTION NMR
Cite:Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor.
Sci Rep, 7, 2017
6NOM
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BU of 6nom by Molmil
NMR solution structure of Pisum sativum defensin 2 (Psd2) provides evidence for the presence of hydrophobic surface clusters
Descriptor: Defensin-2
Authors:Pinheiro-Aguiar, R, Amaral, V.S.G, Bastos, I, Kurtenbach, E, Almeida, F.C.L.
Deposit date:2019-01-16
Release date:2019-08-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance solution structure of Pisum sativum defensin 2 provides evidence for the presence of hydrophobic surface-clusters.
Proteins, 88, 2020
8TYI
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BU of 8tyi by Molmil
NMR structure of L5pG ([p23W, G24W]kalata B1)
Descriptor: Kalata-B1
Authors:Tian, S, Craik, D.J, Conan, K.W.
Deposit date:2023-08-25
Release date:2024-03-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Nucleation of a key beta-turn promotes cyclotide oxidative folding.
J.Biol.Chem., 300, 2024
9AZI
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BU of 9azi by Molmil
NMR solution structure of cell-permeant miniature protein ZF5.3
Descriptor: Designed Zinc finger protein 5.3, ZINC ION
Authors:Giudice, J.A, Kelly, M, Schepartz, A.
Deposit date:2024-03-11
Release date:2024-05-01
Method:SOLUTION NMR
Cite:Structural and mechanistic basis for efficient endosomal escape by designed mini-proteins
To be published
5H7U
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BU of 5h7u by Molmil
NMR structure of eIF3 36-163
Descriptor: Eukaryotic translation initiation factor 3 subunit C
Authors:Nagata, T, Obayashi, E.
Deposit date:2016-11-21
Release date:2017-05-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Cell Rep, 18, 2017
5J8T
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BU of 5j8t by Molmil
NMR structure of Excalibur domain of CbpL
Descriptor: CALCIUM ION, Choline binding protein
Authors:Pantoja-Uceda, D, Trevino, M.A, Bruix, M.
Deposit date:2016-04-08
Release date:2017-05-10
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Molecular Choline-bindind Protein L Involved in Pneumococcal Adhesion and Virulence through Exposed Excalibur domanin
To Be Published
7XGA
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BU of 7xga by Molmil
NMR strucutre of chimeric protein for model of PHD-Stella complex
Descriptor: Chimera of E3 ubiquitin-protein ligase UHRF1 and Developmental pluripotency-associated protein 3, ZINC ION
Authors:Kobayashi, N, Konuma, T, Arita, K.
Deposit date:2022-04-04
Release date:2022-12-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger.
Nucleic Acids Res., 50, 2022
7XFG
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BU of 7xfg by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
Descriptor: Histone acetyltransferase p300, NUT family member 1, ZINC ION
Authors:Yu, D, Zeng, L, Zhou, M.-M.
Deposit date:2022-04-01
Release date:2023-04-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XEZ
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BU of 7xez by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
Descriptor: Histone acetyltransferase p300,NUT family member 1, ZINC ION
Authors:Yu, D, Zeng, L, Zhou, M.-M.
Deposit date:2022-03-31
Release date:2023-04-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
5NR5
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BU of 5nr5 by Molmil
NMR structure and 1H, 13C and 15N signal assignments for Dictyostelium discoideum MATA protein
Descriptor: MatA protein
Authors:Neuhaus, D, Hedgethorne, K, Yang, J.-C.
Deposit date:2017-04-22
Release date:2017-09-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium.
Sci Adv, 3, 2017
5OBN
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BU of 5obn by Molmil
NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)
Descriptor: RNA-binding protein 40
Authors:Norppa, A.J, Kauppala, T.M, Heikkinen, H.A, Verma, B, Iwai, H, Frilander, M.J.
Deposit date:2017-06-28
Release date:2018-01-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
RNA, 24, 2018
6CCH
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BU of 6cch by Molmil
NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-07
Release date:2018-08-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
6I9B
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BU of 6i9b by Molmil
NMR structure of the La module from human LARP4A
Descriptor: La-related protein 4
Authors:Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
5JYV
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BU of 5jyv by Molmil
NMR structure of foldswitch-stablized KaiB in complex with pseudo receiver domain of CikA from Thermosynechococcus elongatus
Descriptor: Circadian clock protein KaiB, Two-component sensor histidine kinase
Authors:Tseng, R.D, LiWang, A.L.
Deposit date:2016-05-15
Release date:2017-03-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of the day-night transition in a bacterial circadian clock.
Science, 355, 2017
7S55
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BU of 7s55 by Molmil
NMR Solution Structure of Cter 27
Descriptor: Cliotide T10
Authors:Harvey, P.J, Dang, T.T, Craik, D.J.
Deposit date:2021-09-09
Release date:2022-07-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides
Peptide Science, 2022
6FZK
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BU of 6fzk by Molmil
NMR structure of UB2H, regulatory domain of PBP1b from E. coli
Descriptor: Penicillin-binding protein 1B
Authors:Simorre, J.P, Maya Martinez, R.C, Bougault, C, Egan, A.J.F, Vollmer, W.
Deposit date:2018-03-15
Release date:2019-02-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Induced conformational changes activate the peptidoglycan synthase PBP1B.
Mol. Microbiol., 110, 2018
6VNZ
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BU of 6vnz by Molmil
NMR solution structure of tamapin, mutant K20A
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Mayorga Flores, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells.
Acs Med.Chem.Lett., 11, 2020
5XE4
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BU of 5xe4 by Molmil
NMR solution structure of the aromatic mutant H43W H67F cytochrome b5
Descriptor: Cytochrome b5
Authors:Balakrishnan, S, Sarma, S.P.
Deposit date:2017-03-31
Release date:2018-02-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Engineering Aromatic-Aromatic Interactions To Nucleate Folding in Intrinsically Disordered Regions of Proteins
Biochemistry, 56, 2017
7P4N
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BU of 7p4n by Molmil
NMR solution structure of the C6 domain of von Willebrand Factor
Descriptor: von Willebrand factor
Authors:Hennig, J, Chen, P.-C, Simon, B.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and dynamics of the von Willebrand Factor C6 domain.
J.Struct.Biol., 214, 2022

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数据于2024-07-10公开中

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