PDB: 13422 resultsInfo pagesStatus searchChemie searchBIRD

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7D4I	Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-24 Release date: 2021-10-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
6R0L	Histone fold domain of OsGhd8/NF-YC7 in I2 Descriptor: GLYCEROL, OsGhd8, OsNF-YC7 Authors: Chaves-Sanjuan, A, Gobbini, A, Nardini, M. Deposit date: 2019-03-13 Release date: 2020-09-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural determinants for NF-Y subunit organization and NF-Y/DNA association in plants. Plant J., 105, 2021
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhan, X, Yan, C, Zhang, X, Shi, Y. Deposit date: 2018-08-15 Release date: 2018-11-14 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
8OHD	60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. Deposit date: 2023-03-21 Release date: 2024-02-21 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
8I0U	The cryo-EM structure of human Bact-IV complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0R	The cryo-EM structure of human Bact-I complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
1W8C	CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL-9H-PURIN-2- YLAMINE AND MONOMERIC CDK2 Descriptor: 6-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINE, CELL DIVISION PROTEIN KINASE 2 Authors: Pratt, D.J, Endicott, J.A, Noble, M.E.M. Deposit date: 2004-09-20 Release date: 2006-08-30 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.05 Å) Cite: 8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode. J.Med.Chem., 57, 2014
8I0T	The cryo-EM structure of human Bact-III complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0S	The cryo-EM structure of human Bact-II complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
6FF7	human Bact spliceosome core structure Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... Authors: Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. Deposit date: 2018-01-03 Release date: 2019-03-13 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
6FEC	Human cap-dependent 48S pre-initiation complex Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Schaffitzel, C, Schaffitzel, C. Deposit date: 2017-12-31 Release date: 2018-03-14 Last modified: 2018-10-03 Method: ELECTRON MICROSCOPY (6.3 Å) Cite: Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
6FF4	human Bact spliceosome core structure Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. Deposit date: 2018-01-03 Release date: 2018-08-29 Last modified: 2020-10-07 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
8B8V	Crystal structure of the Rabies virus RNA free nucleoprotein- phosphoprotein complex Descriptor: DI(HYDROXYETHYL)ETHER, Nucleoprotein, Phosphoprotein Authors: Gerard, F.C.A, Jamin, M, Bourhis, J.M. Deposit date: 2022-10-05 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module. Viruses, 14, 2022
9BDL	80S ribosome with angiogenin Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Loveland, A.B, Korostelev, A.A. Deposit date: 2024-04-12 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural mechanism of angiogenin activation by the ribosome. Nature, 630, 2024
6ZMW	Structure of a human 48S translational initiation complex Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. Deposit date: 2020-07-04 Release date: 2020-09-23 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure of a human 48Stranslational initiation complex. Science, 369, 2020
8I0V	The cryo-EM structure of human post-Bact complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
7Q3L	Human 17S U2 snRNP 5' domain Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-10-28 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.21 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
6YBW	Structure of a human 48S translational initiation complex - 40S body Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... Authors: Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. Deposit date: 2020-03-18 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of a human 48Stranslational initiation complex. Science, 369, 2020
8QOZ	Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-09-29 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
7Q4O	Substrate-bound A-like U2 snRNP Descriptor: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-11-01 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q4P	U2 snRNP after ATP-dependent remodelling Descriptor: PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-11-01 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
8QPK	Cryo-EM Structure of Pre-B+5'ss Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-02 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QPA	Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-01 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QPB	Cryo-EM Structure of Pre-B+ATP Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-01 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
5L9X	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016

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