PDB: 217728 resultsInfo pagesStatus searchChemie searchBIRD

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8JAQ	Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... Authors: Zhao, S, Zhang, K, Xu, C. Deposit date: 2023-05-06 Release date: 2023-10-18 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
8JAS	Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... Authors: Zhao, S, Zhang, K, Xu, C. Deposit date: 2023-05-07 Release date: 2023-10-18 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
3KSQ	Discovery of C-Imidazole Azaheptapyridine FPT Inhibitors Descriptor: FARNESYL DIPHOSPHATE, Farnesyltransferase, CAAX box, ... Authors: Zhu, H.Y, Cooper, A.B, Njoroge, G, Kirschmeier, P, Strickland, C, Hruza, A, Girijavallabhan, V.M. Deposit date: 2009-11-23 Release date: 2010-01-26 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of C-imidazole azaheptapyridine FPT inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
7SYN	Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
7SYJ	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYL	Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYX	Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
1ATL	Structural interaction of natural and synthetic inhibitors with the VENOM METALLOPROTEINASE, ATROLYSIN C (FORM-D) Descriptor: CALCIUM ION, O-methyl-N-[(2S)-4-methyl-2-(sulfanylmethyl)pentanoyl]-L-tyrosine, Snake venom metalloproteinase atrolysin-D, ... Authors: Zhang, D, Botos, I, Gomis-Rueth, F.-X, Doll, R, Blood, C, Njoroge, F.G, Fox, J.W, Bode, W, Meyer, E.F. Deposit date: 1995-05-26 Release date: 1995-10-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Proc.Natl.Acad.Sci.USA, 91, 1994
8EDE	Crystal structure of covalent inhibitor 2-chloro-N'-(N-(4-chlorophenyl)-N-methylglycyl)acetohydrazide bound to Ubiquitin C-terminal Hydrolase-L1 Descriptor: 2-[(4-chlorophenyl)-methyl-amino]-~{N}'-ethanoyl-ethanehydrazide, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L1 Authors: Patel, R, Imhoff, R, Flaherty, D, Das, C. Deposit date: 2022-09-04 Release date: 2023-09-20 Last modified: 2024-04-10 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. J.Med.Chem., 67, 2024
7SYW	Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt) Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYI	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYU	Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYK	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYT	Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYV	Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt) Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-20 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
8UMC	Deinococcus aerius TR0125 C-glucosyl deglycosidase (CGD), cryo-EM Descriptor: DUF6379 domain-containing protein, MANGANESE (II) ION, Xylose isomerase-like TIM barrel domain-containing protein Authors: Furlanetto, V, Kalyani, D.C, Kostelac, A, Haltrich, D, Hallberg, B.M, Divne, C. Deposit date: 2023-10-17 Release date: 2024-05-29 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural and Functional Characterization of a Gene Cluster Responsible for Deglycosylation of C-glucosyl Flavonoids and Xanthonoids by Deinococcus aerius. J.Mol.Biol., 436, 2024
8JAL	Structure of CRL2APPBP2 bound with RxxGP degron (dimer) Descriptor: Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... Authors: Zhao, S, Zhang, K, Xu, C. Deposit date: 2023-05-06 Release date: 2023-10-18 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
1C4L	SOLUTION STRUCTURE OF AN RNA DUPLEX INCLUDING A C-U BASE-PAIR Descriptor: RNA (5'-R(*CP*CP*UP*GP*CP*GP*UP*CP*G)-3'), RNA (5'-R(*CP*GP*AP*CP*UP*CP*AP*GP*G)-3') Authors: Tanaka, Y, Kojima, C, Yamazaki, T, Kodama, T.S, Yasuno, K, Miyashita, S, Ono, A.M, Ono, A.S, Kainosho, M, Kyogoku, Y. Deposit date: 1999-08-30 Release date: 2000-08-09 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of an RNA duplex including a C-U base pair. Biochemistry, 39, 2000
7UJ6	Outer Surface Protein C Type K Descriptor: Outer surface protein C Authors: Rudolph, M.J, Mantis, N. Deposit date: 2022-03-30 Release date: 2023-04-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.951 Å) Cite: Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. Mbio, 14, 2023
6PCM	Crystal Structure of Mycobacterium smegmatis Topoisomerase I with ssDNA bound to both N- and C-terminal domains Descriptor: DNA (5'-D(P*AP*GP*TP*GP*AP*GP*CP*GP*AP*GP*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*CP*TP*T)-3'), DNA topoisomerase 1, SULFATE ION Authors: Tan, K, Cao, N, Tse-Dinh, Y.C. Deposit date: 2019-06-17 Release date: 2020-03-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.107 Å) Cite: Mechanistic insights from structure of Mycobacterium smegmatis topoisomerase I with ssDNA bound to both N- and C-terminal domains. Nucleic Acids Res., 48, 2020
1ALC	REFINED STRUCTURE OF BABOON ALPHA-LACTALBUMIN AT 1.7 ANGSTROMS RESOLUTION. COMPARISON WITH C-TYPE LYSOZYME Descriptor: ALPHA-LACTALBUMIN, CALCIUM ION Authors: Acharya, K.R, Stuart, D.I, Phillips, D.C. Deposit date: 1989-08-14 Release date: 1989-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme. J.Mol.Biol., 208, 1989
8G9S	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: AcrIC8, Cas11, Cas5, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
8G9T	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: AcrIC9, Cas11, Cas5, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
8G9U	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: CRISPR-associated protein, Csd1 family, Csd2 family, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
8GAF	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: Cas11, Cas5, Cas7, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.64 Å) Cite: Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024

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