1FTH
| CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE ACYL CARRIER PROTEIN SYNTHASE (3'5'-ADP COMPLEX) | Descriptor: | ACYL CARRIER PROTEIN SYNTHASE, ADENOSINE-3'-5'-DIPHOSPHATE | Authors: | Chirgadze, N, Briggs, S, McAllister, K, Fischl, A, Zhao, G. | Deposit date: | 2000-09-12 | Release date: | 2001-09-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis. EMBO J., 19, 2000
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1F7L
| HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH COENZYME A AT 1.5A | Descriptor: | CALCIUM ION, CHLORIDE ION, COENZYME A, ... | Authors: | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | Deposit date: | 2000-06-27 | Release date: | 2001-06-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure Fold.Des., 8, 2000
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1F7T
| HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | Authors: | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | Deposit date: | 2000-06-27 | Release date: | 2001-06-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure Fold.Des., 8, 2000
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1FTE
| CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE ACYL CARRIER PROTEIN SYNTHASE (NATIVE 1) | Descriptor: | ACYL CARRIER PROTEIN SYNTHASE, SULFATE ION | Authors: | Chirgadze, N, Briggs, S, McAllister, K, Fischl, A, Zhao, G. | Deposit date: | 2000-09-12 | Release date: | 2001-09-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis. EMBO J., 19, 2000
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2WDS
| Crystal structure of the Streptomyces coelicolor H110A AcpS mutant in complex with cofactor CoA at 1.3 A | Descriptor: | COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-26 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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2WAT
| Structure of the fungal type I FAS PPT domain in complex with CoA | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, CHLORIDE ION, COENZYME A, ... | Authors: | Johansson, P, Mulincacci, B, Koestler, C, Grininger, M. | Deposit date: | 2009-02-15 | Release date: | 2009-08-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multimeric Options for the Auto-Activation of the Saccharomyces Cerevisiae Fas Type I Megasynthase. Structure, 17, 2009
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2WDY
| Crystal structure of the Streptomyces coelicolor D111A AcpS mutant in complex with cofactor CoA at 1.4 A | Descriptor: | COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION, ... | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-27 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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2WAS
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2WDO
| Crystal structure of the S. coelicolor AcpS in complex with acetyl- CoA at 1.5 A | Descriptor: | ACETYL COENZYME *A, COENZYME A, GLYCEROL, ... | Authors: | Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T. | Deposit date: | 2009-03-25 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity. Biochemistry, 50, 2011
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8GKF
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1QR0
| CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX | Descriptor: | 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION | Authors: | Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R. | Deposit date: | 1999-06-17 | Release date: | 1999-12-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily. EMBO J., 18, 1999
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8QZH
| Crystal structure of apo-PptT from Mycobacterium tuberculosis | Descriptor: | 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION | Authors: | Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2023-10-27 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
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8QZJ
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7ED2
| Transferase from Mycobacterium smegmatis | Descriptor: | 4'-phosphopantetheinyl transferase, ADENOSINE-3'-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Kim, D.-G, Lee, B.-J, Lee, S.J. | Deposit date: | 2021-03-15 | Release date: | 2022-03-16 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Transferase from Mycobacterium tuberculosis To Be Published
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7ED1
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7ED0
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7N8L
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7N8E
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7N8M
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4QJK
| Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT | Descriptor: | COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION | Authors: | Noel, J.P, Burkart, M.D, Vickery, C.R. | Deposit date: | 2014-06-04 | Release date: | 2014-07-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria. Acs Chem.Biol., 9, 2014
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4QJL
| Crystal structure of M. ulcerans phosphopantetheinyl transferase MuPPT | Descriptor: | COENZYME A, MAGNESIUM ION, Phosphopantetheinyl transferase, ... | Authors: | Noel, J.P, Burkart, M.D, Vickery, C.R. | Deposit date: | 2014-06-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria. Acs Chem.Biol., 9, 2014
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2C43
| STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A | Descriptor: | AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, CHLORIDE ION, COENZYME A, ... | Authors: | Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Oppermann, U. | Deposit date: | 2005-10-14 | Release date: | 2005-10-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
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2BYD
| Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase | Descriptor: | BROMIDE ION, HSPC223 | Authors: | Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, Oppermann, U, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J. | Deposit date: | 2005-07-29 | Release date: | 2005-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
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4U89
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7B4R
| Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea | Descriptor: | COENZYME A, MANGANESE (II) ION, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ... | Authors: | Maveyraud, L, Carivenc, C, Blanger, C, Mourey, L. | Deposit date: | 2020-12-02 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021
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