PDB: 660 resultsInfo pagesStatus searchChemie searchBIRD

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5ELQ	Crystal structure of the SNX27 PDZ domain bound to the C-terminal DGKzeta PDZ binding motif Descriptor: GLU-ASP-GLN-GLU-THR-ALA-VAL, Sorting nexin-27, TETRAETHYLENE GLYCOL Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-05 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.1 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EM9	Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif Descriptor: SEP-LEU-GLU-SER-CYS-PHE, Sorting nexin-27 Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-06 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
4UU5	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ... Authors: Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. Deposit date: 2014-07-24 Release date: 2015-01-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5EMB	Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif Descriptor: GLU-GLU-TRP-SEP-THR-VAL-MET, Sorting nexin-27 Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-06 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (0.85 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EMA	Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal LRRC3B PDZ binding motif Descriptor: ASP-ASP-ILE-SEP-THR-VAL-VAL, GLYCEROL, Sorting nexin-27 Authors: Collins, B.M, Clairfeuille, T. Deposit date: 2015-11-06 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.32 Å) Cite: A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
4UU6	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. Deposit date: 2014-07-24 Release date: 2015-01-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4WYU	Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide Descriptor: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU Authors: Ren, J.Q, Pei, H.H, Feng, W. Deposit date: 2014-11-18 Release date: 2015-10-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule. Biochem.J., 468, 2015
1D5G	SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE Descriptor: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV Authors: Kozlov, G, Gehring, K, Ekiel, I. Deposit date: 1999-10-07 Release date: 2002-07-24 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions J.Mol.Biol., 320, 2002
8WWR	Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain Descriptor: Segment polarity protein dishevelled homolog DVL-2 Authors: Omble, A, Mahajan, S, Kulkarni, K.A. Deposit date: 2023-10-26 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF. Commun Biol, 7, 2024
1BFE	THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 Descriptor: PSD-95 Authors: Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. Deposit date: 1998-05-20 Release date: 1998-10-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
1B8Q	SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE Descriptor: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE) Authors: Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M. Deposit date: 1999-02-01 Release date: 1999-04-29 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nat.Struct.Biol., 6, 1999
7LUL	Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2021-02-22 Release date: 2021-07-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
6OV7	CFTR Associated Ligand (CAL) PDZ domain bound to peptide kCAL01 Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, kCAL01 peptide Authors: Gill, N.P, Madden, D.R. Deposit date: 2019-05-07 Release date: 2019-11-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand. J.Phys.Chem.B, 123, 2019
7MFW	Drosophila melanogaster Canoe PDZ domain in complex with Echinoid C-terminal region Descriptor: Canoe,Echinoid Authors: Slep, K.C, Peifer, M, Byrnes, A.E. Deposit date: 2021-04-11 Release date: 2021-11-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.104 Å) Cite: Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis. J.Cell Biol., 220, 2021
6Q0N	Structure of the Erbin PDB domain in complex with a high-affinity peptide Descriptor: Erbin, peptide Authors: Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
6Q0U	Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide Descriptor: 1,2-ETHANEDIOL, Erbin, peptide Authors: Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
6Q0M	Structure of Erbin PDZ derivative E-14 with a high-affinity peptide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... Authors: Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2019-08-02 Release date: 2019-11-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
6QJJ	Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3221 Descriptor: Disks large homolog 4, SULFATE ION Authors: Camara-Artigas, A. Deposit date: 2019-01-24 Release date: 2019-04-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95. Acta Crystallogr D Struct Biol, 75, 2019
7NTJ	PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex Descriptor: Envelope small membrane protein, MAGUK p55 subfamily member 5 Authors: Javorsky, A, Kvansakul, M. Deposit date: 2021-03-10 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain. Commun Biol, 4, 2021
7NTK	PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ... Authors: Javorsky, A, Kvansakul, M. Deposit date: 2021-03-10 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain. Commun Biol, 4, 2021
6EEY	Crystal structure of human Scribble PDZ4 R1110G Mutant Descriptor: Protein scribble homolog Authors: Janezic, E.M, Hsu, P, Hague, C. Deposit date: 2018-08-15 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.145 Å) Cite: Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands. Sci Rep, 9, 2019
6UBH	Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide Descriptor: Erbin, SODIUM ION, peptide Authors: Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2019-09-11 Release date: 2020-07-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
5TYT	Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide Descriptor: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera Authors: Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z. Deposit date: 2016-11-21 Release date: 2017-02-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.398 Å) Cite: Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. Biochem. Biophys. Res. Commun., 485, 2017
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. Descriptor: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 Authors: Loew, C, Flayhan, A, Pieprzyk, J. Deposit date: 2017-11-15 Release date: 2018-09-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.503321 Å) Cite: Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
6V84	CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAc Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALAc Authors: Gill, N.P, Madden, D.R. Deposit date: 2019-12-10 Release date: 2021-02-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.64 Å) Cite: CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAc To Be Published

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