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7KAT
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BU of 7kat by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class without Sec62
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAQ
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BU of 7kaq by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 2 (C2)
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAJ
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BU of 7kaj by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 2 (C2)
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAI
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BU of 7kai by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 1 (C1)
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAR
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BU of 7kar by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class without Sec62
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAP
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BU of 7kap by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 1 (C1)
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KB5
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BU of 7kb5 by Molmil
Cryo-EM structure of the Sec complex from yeast, Sec63 FN3 and residues 210-216 mutated
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAU
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BU of 7kau by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class with Sec62
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7AFT
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BU of 7aft by Molmil
Cryo-EM structure of the signal sequence-engaged post-translational Sec translocon
Descriptor: Mating factor alpha-1,Mating factor alpha-1, Protein translocation protein SEC63, Protein transport protein SBH1, ...
Authors:Weng, T.-H, Beatrix, B, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-09-20
Release date:2020-12-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the active post-translational Sec translocon.
Embo J., 40, 2021
7JTK
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BU of 7jtk by Molmil
Radial spoke 1 isolated from Chlamydomonas reinhardtii
Descriptor: Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ...
Authors:Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A.
Deposit date:2020-08-17
Release date:2020-12-16
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of radial spokes and associated complexes important for ciliary motility.
Nat.Struct.Mol.Biol., 28, 2021
6Z5N
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BU of 6z5n by Molmil
DnaJB1 JD-GF
Descriptor: DnaJ homolog subfamily B member 1
Authors:Avraham-Abayev, M, London, N, Rosenzweig, R.
Deposit date:2020-05-27
Release date:2020-11-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:HSP40 proteins use class-specific regulation to drive HSP70 functional diversity.
Nature, 587, 2020
6YXX
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BU of 6yxx by Molmil
State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
Descriptor: 12S ribosomal RNA, 50S ribosomal protein L13, putative, ...
Authors:Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2020-05-04
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
Descriptor: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2020-05-04
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6WJG
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BU of 6wjg by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Descriptor: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
Deposit date:2020-04-13
Release date:2020-12-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
6WJF
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BU of 6wjf by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Descriptor: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
Deposit date:2020-04-13
Release date:2020-12-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
6U3R
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BU of 6u3r by Molmil
Solution NMR structure of the DNAJB6b deltaST variant (Aligned on the J domain)
Descriptor: DnaJ homolog subfamily B member 6,DnaJ homolog subfamily B member 6
Authors:Karamanos, T.K, Clore, G.M.
Deposit date:2019-08-22
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis.
Proc.Natl.Acad.Sci.USA, 116, 2019
6U3S
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BU of 6u3s by Molmil
Solution NMR structure of the DNAJB6b deltaST variant (Aligned on the CTD domain)
Descriptor: DnaJ homolog subfamily B member 6
Authors:Karamanos, T.K, Clore, G.M.
Deposit date:2019-08-22
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PSI
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BU of 6psi by Molmil
Structural Basis for Client Recognition and Activity of Hsp40 Chaperones
Descriptor: Alkaline phosphatase, Chaperone protein DnaJ 2
Authors:Jiang, Y, Rossi, P, Kalodimos, C.G.
Deposit date:2019-07-12
Release date:2019-09-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for client recognition and activity of Hsp40 chaperones.
Science, 365, 2019
6RZY
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BU of 6rzy by Molmil
Plasmodium falciparum PFA0660w Hsp40 co-chaperone J-domain
Descriptor: Heat shock protein 40, type II
Authors:Vakonakis, I, Day, J.
Deposit date:2019-06-13
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.379 Å)
Cite:ThePlasmodium falciparumHsp70-x chaperone assists the heat stress response of the malaria parasite.
Faseb J., 33, 2019
6JZB
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BU of 6jzb by Molmil
Structural characterization of DnaJ from Streptococcus pneumonia presents a new tetramer of Hsp40 family
Descriptor: Chaperone protein DnaJ, ZINC ION
Authors:Zhu, M, Zhu, Z.L.
Deposit date:2019-04-30
Release date:2020-11-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.754 Å)
Cite:Structural insights into the formation of oligomeric state by a type I Hsp40 chaperone.
Biochimie, 176, 2020
6JMG
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BU of 6jmg by Molmil
Crystal structure of xRbj
Descriptor: DnaJ homolog subfamily C member 27-A, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Gao, Z.R, Qi, J.X.
Deposit date:2019-03-09
Release date:2020-03-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of Rbj
To Be Published
6ND1
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BU of 6nd1 by Molmil
CryoEM structure of the Sec Complex from yeast
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Wu, X, Cabanos, C, Rapoport, T.A.
Deposit date:2018-12-13
Release date:2019-01-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the post-translational protein translocation machinery of the ER membrane.
Nature, 566, 2019
6IWS
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BU of 6iws by Molmil
Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein
Descriptor: DnaJ homolog subfamily A member 3, mitochondrial
Authors:Sim, D.W, Jo, K.S, Won, H.S, Kim, J.H.
Deposit date:2018-12-06
Release date:2019-12-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein
To Be Published
6N3Q
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BU of 6n3q by Molmil
Cryo-EM structure of the yeast Sec complex
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Park, E, Itskanov, S.
Deposit date:2018-11-16
Release date:2018-12-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structure of the posttranslational Sec protein-translocation channel complex from yeast.
Science, 363, 2019
6HIX
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BU of 6hix by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit
Descriptor: 12S rRNA, 50S ribosomal protein L13, putative, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018

221051

数据于2024-06-12公开中

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