1QZL
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![BU of 1qzl by Molmil](/molmil-images/mine/1qzl) | GCATGCT + Cobalt | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT (II) ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-17 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1QYL
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![BU of 1qyl by Molmil](/molmil-images/mine/1qyl) | GCATGCT + Vanadium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', VANADIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be Published
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1R2O
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![BU of 1r2o by Molmil](/molmil-images/mine/1r2o) | d(GCATGCT) + Ni2+ | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', NICKEL (II) ION | Authors: | Cardin, J.C, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-29 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1QYK
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![BU of 1qyk by Molmil](/molmil-images/mine/1qyk) | GCATGCT + Barium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', BARIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1N96
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![BU of 1n96 by Molmil](/molmil-images/mine/1n96) | DIMERIC SOLUTION STRUCTURE OF THE CYCLIC OCTAMER CD(CGCTCATT) | Descriptor: | CYCLIC OLIGONUCLEOTIDE D(CGCTCATT) | Authors: | Escaja, N, Gelpi, J.L, Orozco, M, Rico, M, Pedroso, E, Gonzalez, C. | Deposit date: | 2002-11-22 | Release date: | 2003-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Four-stranded DNA structure stabilized by a novel G:C:A:T tetrad. J.Am.Chem.Soc., 125, 2003
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6IP3
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![BU of 6ip3 by Molmil](/molmil-images/mine/6ip3) | Structure of human telomeric DNA at 1.4 Angstroms resolution | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION | Authors: | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | Deposit date: | 2018-11-01 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe. Nucleic Acids Res., 47, 2019
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6ISW
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![BU of 6isw by Molmil](/molmil-images/mine/6isw) | Structure of human telomeric DNA with 5-selenophene-modified deoxyuridine at residue 12 | Descriptor: | DNA (22-MER), POTASSIUM ION | Authors: | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | Deposit date: | 2018-11-19 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe. Nucleic Acids Res., 47, 2019
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6IP7
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![BU of 6ip7 by Molmil](/molmil-images/mine/6ip7) | Structure of human telomeric DNA with 5-Selenophene-modified deoxyuridine at residue 11 | Descriptor: | DNA (22-MER), POTASSIUM ION | Authors: | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | Deposit date: | 2018-11-02 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe. Nucleic Acids Res., 47, 2019
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1V3P
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![BU of 1v3p by Molmil](/molmil-images/mine/1v3p) | Crystal structure of d(GCGAGAGC): the DNA octaplex structure with I-motif of G-quartet | Descriptor: | 5'-D(*GP*(C38)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION | Authors: | Kondo, J, Umeda, S, Sunami, T, Takenaka, A. | Deposit date: | 2003-11-03 | Release date: | 2004-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats Nucleic Acids Res., 32, 2004
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2MCO
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![BU of 2mco by Molmil](/molmil-images/mine/2mco) | Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence | Descriptor: | SODIUM ION, human telomere quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+) L enantiomer | Authors: | Williamson, M.P, Wilson, T, Thomas, J.A, Felix, V, Costa, P.J. | Deposit date: | 2013-08-22 | Release date: | 2013-10-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence. J.Med.Chem., 56, 2013
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2M8Y
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![BU of 2m8y by Molmil](/molmil-images/mine/2m8y) | Structure of d[CGCGAAGCATTCGCG] hairpin | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*GP*CP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Lim, K.W, Phan, A.T. | Deposit date: | 2013-05-30 | Release date: | 2013-07-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis of DNA quadruplex-duplex junction formation. Angew.Chem.Int.Ed.Engl., 52, 2013
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2MS6
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![BU of 2ms6 by Molmil](/molmil-images/mine/2ms6) | Human Telomeric G-quadruplex DNA sequence (TTAGGGT)4 complexed with Flavonoid Quercetin | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DNA_(5'-D(*TP*TP*AP*GP*GP*GP*T)-3') | Authors: | Kumar, A, Tawani, A. | Deposit date: | 2014-07-24 | Release date: | 2015-01-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence Sci Rep, 5, 2015
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2LD8
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![BU of 2ld8 by Molmil](/molmil-images/mine/2ld8) | |
6SX3
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![BU of 6sx3 by Molmil](/molmil-images/mine/6sx3) | Intercalation of heterocyclic ligand between quartets in G-rich tetrahelical structure | Descriptor: | VK2, ~{N}2,~{N}6-bis(1-methylquinolin-1-ium-3-yl)pyridine-2,6-dicarboxamide | Authors: | Kotar, A, Kocman, V, Plavec, J. | Deposit date: | 2019-09-24 | Release date: | 2019-12-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Intercalation of a Heterocyclic Ligand between Quartets in a G-Rich Tetrahelical Structure. Chemistry, 26, 2020
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4DII
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![BU of 4dii by Molmil](/molmil-images/mine/4dii) | X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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4R4A
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![BU of 4r4a by Molmil](/molmil-images/mine/4r4a) | Racemic crystal structure of a cobalt-bound B-DNA duplex | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3', COBALT (II) ION, SPERMINE | Authors: | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | Deposit date: | 2014-08-19 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Racemic DNA crystallography. Angew.Chem.Int.Ed.Engl., 53, 2014
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4R49
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![BU of 4r49 by Molmil](/molmil-images/mine/4r49) | Racemic crystal structure of a calcium-bound B-DNA duplex | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3', CALCIUM ION, SODIUM ION | Authors: | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | Deposit date: | 2014-08-19 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Racemic DNA crystallography. Angew.Chem.Int.Ed.Engl., 53, 2014
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4R48
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![BU of 4r48 by Molmil](/molmil-images/mine/4r48) | Racemic crystal structure of a calcium-bound DNA four-way junction | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3', CALCIUM ION, SODIUM ION | Authors: | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | Deposit date: | 2014-08-19 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Racemic DNA crystallography. Angew.Chem.Int.Ed.Engl., 53, 2014
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4R4D
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![BU of 4r4d by Molmil](/molmil-images/mine/4r4d) | Racemic crystal structure of a magnesium-bound B-DNA duplex | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3', MAGNESIUM ION, SODIUM ION | Authors: | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | Deposit date: | 2014-08-19 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Racemic DNA crystallography. Angew.Chem.Int.Ed.Engl., 53, 2014
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5EW1
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![BU of 5ew1 by Molmil](/molmil-images/mine/5ew1) | Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT3, ... | Authors: | Pica, A, Russo Krauss, I, Parente, V, Sica, F. | Deposit date: | 2015-11-20 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers. Nucleic Acids Res., 45, 2017
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5EW2
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![BU of 5ew2 by Molmil](/molmil-images/mine/5ew2) | Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT12 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT12, ... | Authors: | Pica, A, Russo Krauss, I, Parente, V, Sica, F. | Deposit date: | 2015-11-20 | Release date: | 2016-11-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers. Nucleic Acids Res., 45, 2017
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3BBF
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![BU of 3bbf by Molmil](/molmil-images/mine/3bbf) | Crystal structure of the NM23-H2 transcription factor complex with GDP | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Weichsel, A, Montfort, W.R. | Deposit date: | 2007-11-09 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1. Mol.Cancer Ther., 8, 2009
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3BBB
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![BU of 3bbb by Molmil](/molmil-images/mine/3bbb) | |
3BBC
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![BU of 3bbc by Molmil](/molmil-images/mine/3bbc) | |
4DIH
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![BU of 4dih by Molmil](/molmil-images/mine/4dih) | X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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