PDB: 5554 resultsInfo pagesStatus searchChemie searchBIRD

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7BGB	The H/ACA RNP lobe of human telomerase Descriptor: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... Authors: Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. Deposit date: 2021-01-06 Release date: 2021-04-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
6ZVK	The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ... Authors: Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T. Deposit date: 2020-07-24 Release date: 2020-12-23 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
6GZ3	tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. Deposit date: 2018-07-03 Release date: 2018-12-05 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis. Cell Rep, 25, 2018
8BOT	Cryo-EM structure of NHEJ supercomplex(trimer) Descriptor: DNA (24-MER), DNA (27-MER), DNA (28-MER), ... Authors: Hardwick, S.W, Chaplin, A.K. Deposit date: 2022-11-15 Release date: 2023-06-28 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (7.76 Å) Cite: Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ. Structure, 31, 2023
6YAM	Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... Authors: Bochler, A, Simonetti, A, Guca, E, Hashem, Y. Deposit date: 2020-03-12 Release date: 2020-04-08 Last modified: 2020-04-22 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
6HCQ	Structure of the rabbit collided di-ribosome (collided monosome) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. Deposit date: 2018-08-16 Release date: 2018-10-17 Last modified: 2018-11-14 Method: ELECTRON MICROSCOPY (6.5 Å) Cite: ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
6HCJ	Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... Authors: Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. Deposit date: 2018-08-15 Release date: 2018-10-17 Last modified: 2018-11-14 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
7ABH	Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) Descriptor: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-09 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6ZUO	Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Plassart, L, Shayan, R, Plisson-Chastang, C. Deposit date: 2020-07-23 Release date: 2021-05-12 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZV6	Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Plassart, L, Shayan, R, Plisson-Chastang, C. Deposit date: 2020-07-24 Release date: 2021-05-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6GML	Structure of paused transcription complex Pol II-DSIF-NELF Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. Deposit date: 2018-05-27 Release date: 2018-09-05 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. Deposit date: 2022-02-09 Release date: 2023-02-22 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
7DVQ	Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... Authors: Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. Deposit date: 2021-01-14 Release date: 2021-03-31 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: Structure of the activated human minor spliceosome. Science, 371, 2021
8BPO	Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER) Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S. Deposit date: 2022-11-17 Release date: 2023-07-05 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation. Mol.Cell, 83, 2023
8BHF	Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4 Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S11, ... Authors: Absmeier, E, Chandrasekaran, V, O'Reilly, F.J, Stowell, J.A.W, Rappsilber, J, Passmore, L.A. Deposit date: 2022-10-31 Release date: 2023-09-06 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
7DU2	RNA polymerase III EC complex in post-translocation state Descriptor: DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... Authors: Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. Deposit date: 2021-01-07 Release date: 2021-03-17 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
4BS2	NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA Descriptor: 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3', TAR DNA-BINDING PROTEIN 43 Authors: Lukavsky, P.J, Daujotyte, D, Tollervey, J.R, Ule, J, Stuani, C, Buratti, E, Baralle, F.E, Damberger, F.F, Allain, F.H.T. Deposit date: 2013-06-06 Release date: 2013-11-13 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Molecular Basis of Ug-Rich RNA Recognition by the Human Splicing Factor Tdp-43 Nat.Struct.Mol.Biol., 20, 2013
3X1V	Crystal structure of nucleosome core particle in the presence of histone variant involved in reprogramming Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-28 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.921 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Biochem.Biophys.Res.Commun., 464, 2015
4C9B	Crystal structure of eIF4AIII-CWC22 complex Descriptor: EUKARYOTIC INITIATION FACTOR 4A-III, GLYCEROL, PHOSPHATE ION, ... Authors: Buchwald, G, Schuessler, S, Basquin, C, LeHir, H, Conti, E. Deposit date: 2013-10-02 Release date: 2013-11-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the Human Eif4Aiii-Cwc22 Complex Shows How a Dead-Box Protein is Inhibited by a Mif4G Domain Proc.Natl.Acad.Sci.USA, 110, 2013
4YOE	Structure of UP1 bound to RNA 5'-AGU-3' Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ... Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2015-03-11 Release date: 2015-06-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. J.Mol.Biol., 427, 2015
5A1F	Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine. Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, LYSINE-SPECIFIC DEMETHYLASE 5B, ... Authors: Srikannathasan, V, Johansson, C, Strain-Damerell, C, Gileadi, C, Szykowska, A, Kupinska, K, Kopec, J, Krojer, T, Steuber, H, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2015-04-29 Release date: 2015-05-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12, 2016
5A2Q	Structure of the HCV IRES bound to the human ribosome Descriptor: 18S RRNA, HCV IRES, MAGNESIUM ION, ... Authors: Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. Deposit date: 2015-05-21 Release date: 2015-07-15 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
1NH3	Human Topoisomerase I Ara-C Complex Descriptor: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... Authors: Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. Deposit date: 2002-12-18 Release date: 2003-03-04 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex J.Biol.Chem., 278, 2003
1PO6	Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI) Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Moore, S.A, Shamoo, Y. Deposit date: 2003-06-13 Release date: 2003-11-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.BIOL.CHEM., 278, 2003
1PKM	THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS Descriptor: M1 PYRUVATE KINASE Authors: Allen, S.C, Muirhead, H. Deposit date: 1995-07-13 Release date: 1995-10-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A. Acta Crystallogr.,Sect.D, 52, 1996

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