2HEW
 
 | | The X-ray crystal structure of murine OX40L | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Tumor necrosis factor ligand superfamily member 4 | | Authors: | Hymowitz, S.G, Compaan, D.M. | | Deposit date: | 2006-06-22 | | Release date: | 2006-08-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
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2HFG
 | | Crystal structure of hBR3 bound to CB3s-Fab | | Descriptor: | CB3s Fab heavy chain, CB3s Fab light chain (kappa), Tumor necrosis factor receptor superfamily member 13C | | Authors: | Hymowitz, S.G. | | Deposit date: | 2006-06-23 | | Release date: | 2006-11-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood, 108, 2006
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2HFF
 | | Crystal structure of CB2 Fab | | Descriptor: | CB2 Fab, heavy chain, light chain | | Authors: | Hymowitz, S.G. | | Deposit date: | 2006-06-23 | | Release date: | 2006-11-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood, 108, 2006
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3LN4
 | | Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2 | | Descriptor: | 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ... | | Authors: | Theodossis, A, Gras, S, Rossjohn, J. | | Deposit date: | 2010-02-01 | | Release date: | 2010-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.296 Å) | | Cite: | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
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3LN5
 | | Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase | | Descriptor: | 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Theodossis, A, Gras, S, Rossjohn, J. | | Deposit date: | 2010-02-02 | | Release date: | 2010-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
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3K48
 | | Crystal structure of APRIL bound to a peptide | | Descriptor: | Tumor necrosis factor ligand superfamily member 13, peptide | | Authors: | Hymowitz, S.G. | | Deposit date: | 2009-10-05 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.
J.Mol.Biol., 396, 2010
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3HO5
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3HO4
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3L95
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3DVN
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3DVG
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3HL5
 | | Crystal structure of XIAP BIR3 with CS3 | | Descriptor: | (3S)-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-3-methyl-N-(2-pyrimidin-2-ylphenyl)-L-prolinamide, Baculoviral IAP repeat-containing protein 4, ZINC ION | | Authors: | Hymowitz, S.G. | | Deposit date: | 2009-05-26 | | Release date: | 2009-06-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.
Acs Chem.Biol., 4, 2009
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1VSB
 | | SUBTILISIN CARLSBERG L-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | | Descriptor: | SUBTILISIN CARLSBERG, TYPE VIII | | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | | Deposit date: | 1997-09-17 | | Release date: | 1998-03-18 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
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1GHB
 | | A SECOND ACTIVE SITE IN CHYMOTRYPSIN? THE X-RAY CRYSTAL STRUCTURE OF N-ACETYL-D-TRYPTOPHAN BOUND TO GAMMA-CHYMOTRYPSIN | | Descriptor: | ACETYL GROUP, GAMMA-CHYMOTRYPSIN, HEXANE, ... | | Authors: | Yennawar, H.P, Yennawar, N.H, Farber, G.K. | | Deposit date: | 1994-04-06 | | Release date: | 1994-06-22 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A STRUCTURAL EXPLANATION FOR ENZYME MEMORY IN NONAQUEOUS SOLVENTS.
J.Am.Chem.Soc., 117, 1995
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1EUF
 | | BOVINE DUODENASE(NEW SERINE PROTEASE), CRYSTAL STRUCTURE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DUODENASE, PHOSPHATE ION | | Authors: | Pletnev, V.Z, Zamolodchikova, T.S, Pangborn, W.A, Duax, W.L. | | Deposit date: | 2000-04-14 | | Release date: | 2001-04-14 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of bovine duodenase, a serine protease, with dual trypsin and chymotrypsin-like specificities.
Proteins, 41, 2000
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1EST
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7AL0
 | | Crystal Structure of Heymonin, a Novel Frog-derived Peptide | | Descriptor: | CHLORIDE ION, Heymonin | | Authors: | Kascakova, B, Prudnikova, T, Kuta Smatanova, I, Xu, X. | | Deposit date: | 2020-10-03 | | Release date: | 2021-04-21 | | Last modified: | 2021-05-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties.
Elife, 10, 2021
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1TAW
 | | BOVINE TRYPSIN COMPLEXED TO APPI | | Descriptor: | CALCIUM ION, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR, TRYPSIN | | Authors: | Hynes, T.R, Kossiakoff, A.A. | | Deposit date: | 1996-12-19 | | Release date: | 1997-06-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
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2LSB
 | | Solution-state NMR structure of the human prion protein | | Descriptor: | Major prion protein | | Authors: | Biljan, I, Ilc, G, Giancin, G, Zhukov, I, Plavec, J, Legname, G. | | Deposit date: | 2012-04-26 | | Release date: | 2012-06-27 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism.
Biochem.J., 446, 2012
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1SQK
 | | CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F. | | Deposit date: | 2004-03-19 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly
Cell(Cambridge,Mass.), 117, 2004
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6AB5
 | | Cryo-EM structure of T=1 Penaeus vannamei nodavirus | | Descriptor: | Capsid protein | | Authors: | Chen, N.C, Miyazaki, N, Yoshimura, M, Guan, H.H, Lin, C.C, Iwasaki, K, Chen, C.J. | | Deposit date: | 2018-07-20 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism.
Commun Biol, 2, 2019
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4KFF
 | | Crystal structure of Hansenula polymorpha copper amine oxidase-1 reduced by methylamine at pH 8.5 | | Descriptor: | COPPER (II) ION, GLYCEROL, Peroxisomal primary amine oxidase | | Authors: | Johnson, B.J, Yukl, E.T, Klema, V.J, Wilmot, C.M. | | Deposit date: | 2013-04-26 | | Release date: | 2013-08-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural evidence for the semiquinone in a copper amine oxidase from Hansenula polymorpha: implications for the catalytic mechanism
J.Biol.Chem., 2013
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4KFE
 | | Crystal structure of Hansenula polymorpha copper amine oxidase-1 reduced by methylamine at pH 7.0 | | Descriptor: | COPPER (II) ION, FORMYL GROUP, GLYCEROL, ... | | Authors: | Johnson, B.J, Yukl, E.T, Klema, V.J, Wilmot, C.M. | | Deposit date: | 2013-04-26 | | Release date: | 2013-08-21 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural evidence for the semiquinone in a copper amine oxidase from Hansenula polymorpha: implications for the catalytic mechanism
J.Biol.Chem., 2013
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7B7V
 | | Structure of NUDT15 in complex with Acyclovir monophosphate | | Descriptor: | 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Rehling, D, Stenmark, P. | | Deposit date: | 2020-12-11 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir.
Nat Commun, 12, 2021
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4BKL
 | | Crystal structure of the arthritogenic antibody M2139 (Fab fragment) in complex with the triple-helical J1 peptide | | Descriptor: | J1 EPITOPE, M2139 FAB FRAGMENT HEAVY CHAIN, M2139 FAB FRAGMENT LIGHT CHAIN | | Authors: | Raposo, B, Dobritzsch, D, Ge, C, Ekman, D, Lindh, I, Foerster, M, Uysal, H, Schneider, G, Holmdahl, R. | | Deposit date: | 2013-04-26 | | Release date: | 2014-02-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Epitope-Specific Antibody Response is Controlled by Immunoglobulin Vh Polymorphisms.
J.Exp.Med., 211, 2014
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