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2HUZ
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Crystal structure of GNPNAT1
Descriptor: Glucosamine 6-phosphate N-acetyltransferase
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-07-27
Release date:2006-08-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of glucosamine-phosphate N-acetyltransferase 1
To be Published
2HU4
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BU of 2hu4 by Molmil
N1 neuraminidase in complex with oseltamivir 2
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
Authors:Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2Z1B
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BU of 2z1b by Molmil
Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs
Descriptor: Delta-aminolevulinic acid dehydratase
Authors:Xie, Y, Wang, H, Kawazoe, M, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirozu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-08
Release date:2008-05-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs
To be Published
2I4I
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BU of 2i4i by Molmil
Crystal Structure of human DEAD-box RNA helicase DDX3X
Descriptor: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X
Authors:Hogbom, M, Karlberg, T, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2006-08-22
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
J.Mol.Biol., 372, 2007
2Z2I
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Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis
Descriptor: Peptidyl-tRNA hydrolase
Authors:Selvaraj, M, Roy, S, Singh, N.S, Sangeetha, R, Varshney, U, Vijayan, M.
Deposit date:2007-05-22
Release date:2007-07-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Plasticity and Enzyme Action: Crystal Structures of Mycobacterium tuberculosis Peptidyl-tRNA Hydrolase
J.Mol.Biol., 372, 2007
2Z64
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BU of 2z64 by Molmil
Crystal structure of mouse TLR4 and mouse MD-2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
Authors:Lee, J.-O, Kim, H.M, Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2Z32
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Crystal structure of Keap1 complexed with Prothymosin alpha
Descriptor: Kelch-like ECH-associated protein 1, Prothymosin alpha, SULFATE ION
Authors:Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-31
Release date:2008-03-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of the complex of Keap1 with a prothymosin alpha peptide
Acta Crystallogr.,Sect.F, 64, 2008
2ZIR
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Crystal Structure of rat protein farnesyltransferase complexed with a benzofuran inhibitor and FPP
Descriptor: 2-[(S)-(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-N-morpholin-4-yl-7-phenyl-1-benzofuran-5-carboxamide, FARNESYL DIPHOSPHATE, GLYCEROL, ...
Authors:Fukami, T.A, Sogabe, S, Nagata, Y, Kondoh, O, Ishii, N.
Deposit date:2008-02-22
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
2ZJS
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Crystal Structure of SecYE translocon from Thermus thermophilus with a Fab fragment
Descriptor: Fab56 (heavy chain), Fab56 (light chain), Preprotein translocase SecE subunit, ...
Authors:Tsukazaki, T, Mori, H, Fukai, S, Ishitani, R, Perederina, A, Vassylyev, D.G, Ito, K, Nureki, O.
Deposit date:2008-03-08
Release date:2008-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational transition of Sec machinery inferred from bacterial SecYE structures
Nature, 455, 2008
2HYJ
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BU of 2hyj by Molmil
The crystal structure of a tetR-family transcriptional regulator from Streptomyces coelicolor
Descriptor: CALCIUM ION, Putative tetR-family transcriptional regulator, SULFATE ION
Authors:Zhang, R, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-08-06
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The crystal structure of a tetR-family transcriptional regulator from Streptomyces coelicolor
To be Published, 2006
2I52
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BU of 2i52 by Molmil
Crystal structure of protein PTO0218 from Picrophilus torridus, Pfam DUF372
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ramagopal, U.A, Gilmore, J, Toro, R, Bain, K.T, McKenzie, C, Reyes, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-23
Release date:2006-09-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of hypothetical protein PTO0218 from Picrophilus torridus
To be Published
2I8E
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BU of 2i8e by Molmil
Structure of SSO1404, a predicted DNA repair-associated protein from Sulfolobus solfataricus P2
Descriptor: Hypothetical protein, IODIDE ION
Authors:Wang, S, Zimmerman, M.D, Kudritska, M, Chruszcz, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-01
Release date:2006-09-26
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
J.Biol.Chem., 283, 2008
2Z3F
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Crystal structure of spCia1/Asf1 complexed with Cac2 peptide
Descriptor: Histone chaperone cia1, SPAC26H5.03 protein
Authors:Malay, A.D, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-06-04
Release date:2008-03-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Fission Yeast Histone Chaperone Asf1 Complexed with the Hip1 B-domain or the Cac2 C Terminus
J.Biol.Chem., 283, 2008
2ZUW
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BU of 2zuw by Molmil
Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GlcNAc and sulfate
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, GLYCEROL, Lacto-N-biose phosphorylase, ...
Authors:Hidaka, M, Nishimoto, M, Kitaoka, M, Wakagi, T, Shoun, H, Fushinobu, S.
Deposit date:2008-10-28
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The crystal structure of galacto-N-biose/lacto-N-biose I phosphorylase: A large deformation of a tim barrel scaffold
J.Biol.Chem., 284, 2009
2Z4S
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BU of 2z4s by Molmil
Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosomal replication initiator protein dnaA, MAGNESIUM ION
Authors:Fujikawa, N, Ozaki, S, Kagawa, W, Park, S.-Y, Katayama, T, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-06-25
Release date:2008-02-19
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Common Mechanism for the ATP-DnaA-dependent Formation of Open Complexes at the Replication Origin.
J.Biol.Chem., 283, 2008
2Z55
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BU of 2z55 by Molmil
Bacterioruberin in the trimeric structure of archaerhodopsin-2
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Archaerhodopsin-2, BACTERIORUBERIN, ...
Authors:Kouyama, T, Yoshimura, K.
Deposit date:2007-06-28
Release date:2008-01-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-2
J.Mol.Biol., 375, 2008
2HZA
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BU of 2hza by Molmil
Nickel-bound full-length Escherichia coli NikR
Descriptor: 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, NICKEL (II) ION, Nickel-responsive regulator
Authors:Schreiter, E.R, Drennan, C.L.
Deposit date:2006-08-08
Release date:2006-08-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NikR-operator complex structure and the mechanism of repressor activation by metal ions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I1U
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BU of 2i1u by Molmil
Mycobacterium tuberculosis thioredoxin C
Descriptor: Thioredoxin
Authors:Hall, G, McEwan, P.A, Emsley, J.
Deposit date:2006-08-15
Release date:2006-12-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of Mycobacterium tuberculosisthioredoxin C.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2ZFC
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BU of 2zfc by Molmil
X-ray crystal structure of an engineered N-terminal HIV-1 GP41 trimer with enhanced stability and potency
Descriptor: HIV-1 GP41
Authors:Dwyer, J.J, Wilson, K.L, Martin, K, Seedorff, J.E, Hasan, A, Kim, H.
Deposit date:2007-12-29
Release date:2008-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency
Protein Sci., 17, 2008
2ZGD
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BU of 2zgd by Molmil
Asn-hydroxylation stabilises the ankyrin repeat domain fold
Descriptor: 3 repeat synthetic ankyrin, CADMIUM ION, CHLORIDE ION
Authors:McDonough, M.A, Schofield, C.J.
Deposit date:2008-01-21
Release date:2008-02-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold
Mol Biosyst, 5, 2009
353D
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BU of 353d by Molmil
CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE
Descriptor: RNA (5'-R(*AP*UP*CP*CP*CP*CP*CP*GP*UP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*CP*GP*GP*GP*GP*GP*AP*U)-3')
Authors:Betzel, C, Lorenz, S, Furste, J.P, Bald, R, Zhang, M, Schneider, T.R, Wilson, K.S, Erdmann, V.A.
Deposit date:1997-09-29
Release date:1997-11-10
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure.
FEBS Lett., 351, 1994
2EYX
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BU of 2eyx by Molmil
C-Terminal SH3 domain of CT10-Regulated Kinase
Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:2005-11-10
Release date:2006-11-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2EYV
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BU of 2eyv by Molmil
SH2 domain of CT10-Regulated Kinase
Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:2005-11-10
Release date:2006-11-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2FCV
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SyrB2 with Fe(II), bromide, and alpha-ketoglutarate
Descriptor: ((2R,3S,4S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-5-((2R,3S,4S,5S,6R)-3,4,5-TRIHYDROXY-6-METHOXY-TETRAHYDRO-2H-PYRAN-2-YLOXY)-TETRAHYDROFURAN-2-YL)METHYL NONANOATE, 2-OXOGLUTARIC ACID, BROMIDE ION, ...
Authors:Blasiak, L.C, Drennan, C.L.
Deposit date:2005-12-12
Release date:2006-03-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
Nature, 440, 2006
2FFG
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Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
Descriptor: ykuJ
Authors:Kuzin, A.P, Abashidze, M, Forouhar, F, Vorobiev, S.M, Ho, C.K, Janjua, H, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-12-19
Release date:2005-12-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
To be Published

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数据于2024-11-06公开中

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