PDB: 45522 resultsInfo pagesStatus searchChemie searchBIRD

---

1ZJI	Aquifex aeolicus KDO8PS R106G mutant in complex with 2PGA and R5P Descriptor: 2-PHOSPHOGLYCERIC ACID, 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, ... Authors: Xu, X, Kona, F, Wang, J, Lu, J, Stemmler, T, Gatti, D.L. Deposit date: 2005-04-28 Release date: 2005-09-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.25 Å) Cite: The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop Biochemistry, 44, 2005
1Z0I	GDP-Bound Rab21 GTPase Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-21 Authors: Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. Deposit date: 2005-03-01 Release date: 2005-07-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
1ZK5	Escherichia coli F17fG lectin domain complex with N-acetylglucosamine Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit Authors: Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. Deposit date: 2005-05-02 Release date: 2006-05-02 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Impact of natural variation in bacterial F17G adhesins on crystallization behaviour. Acta Crystallogr.,Sect.D, 61, 2005
1ZA5	Q69H-FeSOD Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, Superoxide dismutase [Fe] Authors: Yikilmaz, E, Rodgers, D.W, Miller, A.F. Deposit date: 2005-04-05 Release date: 2006-03-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Crucial Importance of Chemistry in the Structure-Function Link: Manipulating Hydrogen Bonding in Iron-Containing Superoxide Dismutase. Biochemistry, 45, 2006
1M30	Solution structure of N-terminal SH3 domain from oncogene protein c-Crk Descriptor: Proto-oncogene C-crk Authors: Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. Deposit date: 2002-06-26 Release date: 2003-08-05 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain To be Published
1M3C	Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk Descriptor: Proto-oncogene C-crk Authors: Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. Deposit date: 2002-06-27 Release date: 2003-08-05 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain To be Published
1M63	Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ... Authors: Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H. Deposit date: 2002-07-12 Release date: 2002-09-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes Proc.Natl.Acad.Sci.USA, 99, 2002
222L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
230L	T4 LYSOZYME MUTANT M6L Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Lipscomb, L.A, Gassner, N.C, Snow, S, Eldridge, A.M, Drew, D.L, Baase, W.A, Matthews, B.W. Deposit date: 1997-10-02 Release date: 1998-01-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
1M7G	Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE-2',3'-VANADATE, ADENOSINE-5'-PHOSPHOSULFATE, ... Authors: Lansdon, E.B, Segel, I.H, Fisher, A.J. Deposit date: 2002-07-19 Release date: 2002-11-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Ligand-Induced Structural Changes in Adenosine 5'-Phosphosulfate Kinase from Penicillium chrysogenum. Biochemistry, 41, 2002
1M7H	Crystal Structure of APS kinase from Penicillium Chrysogenum: Structure with APS soaked out of one dimer Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, Adenylylsulfate kinase, ... Authors: Lansdon, E.B, Sege, I.H, Fisher, A.J. Deposit date: 2002-07-19 Release date: 2002-11-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Ligand-Induced Structural Changes in Adenosine 5'-Phosphosulfate Kinase from Penicillium chrysogenum. Biochemistry, 41, 2002
1M7Q	Crystal structure of p38 MAP kinase in complex with a dihydroquinazolinone inhibitor Descriptor: 1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERAZIN-1-YL-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE, Mitogen-activated protein kinase 14, SULFATE ION Authors: Stelmach, J.E, Liu, L, Patel, S.B, Pivnichny, J.V, Scapin, G, Singh, S, Hop, C.E.C.A, Wang, Z, Cameron, P.M, Nichols, E.A, O'Keefe, S.J, O'Neill, E.A, Schmatz, D.M, Schwartz, C.D, Thompson, C.M, Zaller, D.M, Doherty, J.B. Deposit date: 2002-07-22 Release date: 2002-12-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 13, 2003
268D	STRUCTURAL STUDIES ON NUCLEIC ACIDS Descriptor: BERENIL, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3'), MAGNESIUM ION Authors: Partridge, B.L, Salisbury, S.A. Deposit date: 1996-07-12 Release date: 1996-08-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: To be Published, 1996
2A2X	Orally Active Thrombin Inhibitors in Complex with Thrombin Inh12 Descriptor: N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({6-[AMINO(IMINO)METHYL]PYRIDIN-3-YL}METHYL)-N~2~-METHYL-L-ALANINAMIDE, Thrombin heavy chain, Thrombin light chain, ... Authors: Lange, U.E.W, Baucke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W. Deposit date: 2005-06-23 Release date: 2006-11-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety BIOORG.MED.CHEM.LETT., 16, 2006
1MFZ	Partially refined 2.8 A Crystal structure of GDP-mannose dehydrogenase from P. aeruginosa Descriptor: GDP-mannose 6-dehydrogenase, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER Authors: Snook, C.F, Tipton, P.A, Beamer, L.J. Deposit date: 2002-08-14 Release date: 2003-05-06 Last modified: 2014-11-12 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The crystal structure of GDP-mannose dehydrogenase: A key enzyme in alginate biosynthesis of P. aeruginosa Biochemistry, 42, 2003
1MI7	Crystal Structure of Domain Swapped trp Aporepressor in 30%(v/v) Isopropanol Descriptor: ISOPROPYL ALCOHOL, Trp operon repressor Authors: Lawson, C.L, Benoff, B, Berger, T, Berman, H.M, Carey, J. Deposit date: 2002-08-22 Release date: 2003-09-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: E. coli trp repressor forms a domain-swapped array in aqueous alcohol. Structure, 12, 2004
2A97	Crystal structure of catalytic domain of Clostridium botulinum neurotoxin serotype F Descriptor: Botulinum neurotoxin type F, CADMIUM ION, ZINC ION Authors: Agarwal, R, Binz, T, Swaminathan, S. Deposit date: 2005-07-11 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural analysis of botulinum neurotoxin serotype f light chain: implications on substrate binding and inhibitor design Biochemistry, 44, 2005
1ZZ1	Crystal structure of a HDAC-like protein with SAHA bound Descriptor: Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ... Authors: Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. Deposit date: 2005-06-13 Release date: 2005-11-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
2AA9	EPSP synthase liganded with shikimate Descriptor: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID Authors: Priestman, M.A, Healy, M.L, Funke, T, Becker, A, Schonbrunn, E. Deposit date: 2005-07-13 Release date: 2006-02-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. Febs Lett., 579, 2005
227L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
1J0F	Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3 Descriptor: SH3 domain-binding glutamic acid-rich-like protein 3 Authors: Miyamoto, K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2002-11-12 Release date: 2003-12-02 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3 To be Published
1IN2	Peptide Antagonist of IGFBP1, (i,i+7) Covalently Restrained Analog Descriptor: IGFBP-1 antagonist, PENTANE Authors: Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B. Deposit date: 2001-05-11 Release date: 2001-05-30 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1. Biochemistry, 40, 2001
232D	THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGGCATGCCT) Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*AP*GP*GP*CP*AP*TP*GP*CP*CP*T)-3') Authors: Nunn, C.M, Neidle, S. Deposit date: 1995-09-05 Release date: 1996-03-22 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The high resolution crystal structure of the DNA decamer d(AGGCATGCCT). J.Mol.Biol., 256, 1996
236D	CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK Descriptor: 3'-DESAMINO-3'-(3-CYANO-4-MORPHOLINYL)-DOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') Authors: Gao, Y.-G, Wang, A.H.-J. Deposit date: 1995-06-22 Release date: 1996-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink. J.Biomol.Struct.Dyn., 13, 1995
269D	STRUCTURAL STUDIES ON NUCLEIC ACIDS Descriptor: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3'), MAGNESIUM ION Authors: Partridge, B.L, Salisbury, S.A. Deposit date: 1996-07-12 Release date: 1996-08-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.15 Å) Cite: To be Published, 1996

<1767176817691770177117721773177417751776177717781779178017811782>