4FTH
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![BU of 4fth by Molmil](/molmil-images/mine/4fth) | Crystal Structure of NtrC4 DNA-binding domain bound to double-stranded DNA | Descriptor: | 5'-D(*AP*CP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*GP*CP*AP*T)-3', 5'-D(P*GP*AP*TP*GP*CP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*A)-3', Transcriptional regulator (NtrC family) | Authors: | Vidangos, N.K, Heideker, J, Lyubimov, A.Y, Lamers, M, Huo, Y, Pelton, J.G, Ton, J, Gralla, J.D, Kuriyan, J, Berger, J.M, Wemmer, D.E. | Deposit date: | 2012-06-27 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | DNA Recognition by a sigma (54) Transcriptional Activator from Aquifex aeolicus. J.Mol.Biol., 426, 2014
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4O41
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![BU of 4o41 by Molmil](/molmil-images/mine/4o41) | Amide linked RNA | Descriptor: | AMIDE LINKED RNA, STRONTIUM ION | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2013-12-18 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Res., 42, 2014
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4NLE
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![BU of 4nle by Molmil](/molmil-images/mine/4nle) | |
4NC6
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![BU of 4nc6 by Molmil](/molmil-images/mine/4nc6) | |
4NCV
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![BU of 4ncv by Molmil](/molmil-images/mine/4ncv) | Foldon domain wild type N-conjugate | Descriptor: | Fibritin | Authors: | Graewert, M.A, Berthelmann, A, Lach, J, Groll, M, Eichler, J. | Deposit date: | 2013-10-25 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer. Org.Biomol.Chem., 12, 2014
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4NFP
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![BU of 4nfp by Molmil](/molmil-images/mine/4nfp) | Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 8-aza-7-deaza-7-ethynyl Adenosine | Descriptor: | FORMAMIDE, GCAG(A7E)CUUAAGUCUGC | Authors: | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | Deposit date: | 2013-10-31 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA. Acs Chem.Biol., 9, 2014
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4NPS
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![BU of 4nps by Molmil](/molmil-images/mine/4nps) | Crystal Structure of Bep1 protein (VirB-translocated Bartonella effector protein) from Bartonella clarridgeiae | Descriptor: | ACETATE ION, Bartonella effector protein (Bep) substrate of VirB T4SS | Authors: | Dranow, D.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2013-11-22 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
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4NFQ
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![BU of 4nfq by Molmil](/molmil-images/mine/4nfq) | Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 7-triazolyl-8-aza-7-deazaadenosine | Descriptor: | GCAG(7AT)CUUAAGUCUGC | Authors: | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | Deposit date: | 2013-10-31 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA. Acs Chem.Biol., 9, 2014
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4G1P
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![BU of 4g1p by Molmil](/molmil-images/mine/4g1p) | Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae | Descriptor: | CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ... | Authors: | Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S. | Deposit date: | 2012-07-11 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.547 Å) | Cite: | Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae To be published
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4NJ3
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![BU of 4nj3 by Molmil](/molmil-images/mine/4nj3) | |
4NNC
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![BU of 4nnc by Molmil](/molmil-images/mine/4nnc) | Ternary complex of ObcA with C4-CoA adduct and oxalate | Descriptor: | (3S)-3-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-3-oxidanyl-butanoic acid, COBALT (II) ION, OBCA, ... | Authors: | Oh, J.T, Goo, E, Hwang, I, Rhee, S. | Deposit date: | 2013-11-17 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.279 Å) | Cite: | Structural Basis for Bacterial Quorum Sensing-mediated Oxalogenesis. J.Biol.Chem., 289, 2014
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4NP8
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![BU of 4np8 by Molmil](/molmil-images/mine/4np8) | Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph) | Descriptor: | Microtubule-associated protein tau | Authors: | Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N. | Deposit date: | 2013-11-20 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16, 2009
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4O0J
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![BU of 4o0j by Molmil](/molmil-images/mine/4o0j) | HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid | Descriptor: | (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION | Authors: | Feng, L, Kvaratskhelia, M. | Deposit date: | 2013-12-13 | Release date: | 2014-07-02 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase. Plos Pathog., 10, 2014
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4JUO
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![BU of 4juo by Molmil](/molmil-images/mine/4juo) | A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32 | Descriptor: | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, ... | Authors: | Laponogov, I, Veselkov, D.A, Pan, X.-S, Crevel, I, Fisher, L.M, Sanderson, M.R. | Deposit date: | 2013-03-25 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (6.53 Å) | Cite: | Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. Nucleic Acids Res., 41, 2013
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4NVR
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![BU of 4nvr by Molmil](/molmil-images/mine/4nvr) | 2.22 Angstrom Resolution Crystal Structure of a Putative Acyltransferase from Salmonella enterica | Descriptor: | CALCIUM ION, CHLORIDE ION, Putative acyltransferase | Authors: | Minasov, G, Wawrzak, Z, Skarina, T, Gordon, E, Stam, J, Kwon, K, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-12-05 | Release date: | 2013-12-18 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | 2.22 Angstrom Resolution Crystal Structure of a Putative Acyltransferase from Salmonella enterica. TO BE PUBLISHED
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4JUY
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![BU of 4juy by Molmil](/molmil-images/mine/4juy) | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 | Descriptor: | E3 ubiquitin-protein ligase RNF31, UNKNOWN ATOM OR ION | Authors: | Dong, A, Hu, J, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2013-03-25 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 To be Published
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4NPD
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![BU of 4npd by Molmil](/molmil-images/mine/4npd) | High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature | Descriptor: | Immunoglobulin G-binding protein A, THIOCYANATE ION, ZINC ION | Authors: | Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C. | Deposit date: | 2013-11-21 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity. Structure, 22, 2014
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4JC3
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![BU of 4jc3 by Molmil](/molmil-images/mine/4jc3) | |
4J7T
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![BU of 4j7t by Molmil](/molmil-images/mine/4j7t) | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | Descriptor: | D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ... | Authors: | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | Deposit date: | 2013-02-14 | Release date: | 2014-01-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.203 Å) | Cite: | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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4NQV
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![BU of 4nqv by Molmil](/molmil-images/mine/4nqv) | |
4JHC
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![BU of 4jhc by Molmil](/molmil-images/mine/4jhc) | Crystal structure of the uncharacterized Maf protein YceF from E. coli | Descriptor: | GLYCEROL, Maf-like protein YceF, UNKNOWN ATOM OR ION | Authors: | Dong, A, Xu, X, Cui, H, Tchigvintsev, A, Flick, R, Brown, G, Popovic, A, Yakunin, A.F, Savchenko, A. | Deposit date: | 2013-03-04 | Release date: | 2013-03-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Biochemical and structural studies of conserved maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chem.Biol., 20, 2013
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4JAZ
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![BU of 4jaz by Molmil](/molmil-images/mine/4jaz) | Crystal structure of the complex between PPARgamma LBD and trans-resveratrol | Descriptor: | Peroxisome proliferator-activated receptor gamma, RESVERATROL | Authors: | Pochetti, G, Capelli, D, Montanari, R, Calleri, E, Moaddel, R, Temporini, C. | Deposit date: | 2013-02-19 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Resveratrol and Its Metabolites Bind to PPARs. Chembiochem, 15, 2014
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4NPE
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![BU of 4npe by Molmil](/molmil-images/mine/4npe) | High-resolution structure of C domain of staphylococcal protein A at room temperature | Descriptor: | Immunoglobulin G-binding protein A, THIOCYANATE ION, ZINC ION | Authors: | Deis, L.N, Pemble IV, C.W, Oas, T.G, Richardson, J.S, Richardson, D.C. | Deposit date: | 2013-11-21 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity. Structure, 22, 2014
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4NYF
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![BU of 4nyf by Molmil](/molmil-images/mine/4nyf) | HIV integrase in complex with inhibitor | Descriptor: | (2S)-tert-butoxy[4-(4-chlorophenyl)-2-methylquinolin-3-yl]ethanoic acid, CADMIUM ION, Integrase | Authors: | Coulombe, R, Fader, L. | Deposit date: | 2013-12-10 | Release date: | 2014-06-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1. ACS Med Chem Lett, 5, 2014
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4JPC
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![BU of 4jpc by Molmil](/molmil-images/mine/4jpc) | Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors | Descriptor: | 3-[(4R)-2'-amino-1',2,2-trimethyl-5'-oxo-1',2,3,5'-tetrahydrospiro[chromene-4,4'-imidazol]-6-yl]benzonitrile, Beta-secretase 1, NICKEL (II) ION | Authors: | Vigers, G.P.A, Smith, D. | Deposit date: | 2013-03-19 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid beta in a higher species. J.Med.Chem., 56, 2013
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