7LBC
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![BU of 7lbc by Molmil](/molmil-images/mine/7lbc) | Structure of human GGT1 in complex with Lnt2-65 compound | Descriptor: | (2R)-2-[(2-aminoethyl)amino]-4-boronobutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Terzyan, S.S, Hanigan, M. | Deposit date: | 2021-01-07 | Release date: | 2022-02-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase. Bioorg.Med.Chem., 73, 2022
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7LIT
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![BU of 7lit by Molmil](/molmil-images/mine/7lit) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S7G | Descriptor: | Maritimacin, RIBOFLAVIN | Authors: | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | Deposit date: | 2021-01-27 | Release date: | 2022-02-09 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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3HE1
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![BU of 3he1 by Molmil](/molmil-images/mine/3he1) | Secreted protein Hcp3 from Pseudomonas aeruginosa. | Descriptor: | GLYCEROL, Major exported Hcp3 protein | Authors: | Osipiuk, J, Xu, X, Cui, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-05-07 | Release date: | 2009-06-16 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Crystal structure of secretory protein Hcp3 from Pseudomonas aeruginosa. J.Struct.Funct.Genom., 12, 2011
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2FNO
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![BU of 2fno by Molmil](/molmil-images/mine/2fno) | |
3HD0
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![BU of 3hd0 by Molmil](/molmil-images/mine/3hd0) | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima | Descriptor: | Endonuclease V | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2009-05-06 | Release date: | 2009-07-14 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima To be Published
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5VY7
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![BU of 5vy7 by Molmil](/molmil-images/mine/5vy7) | A self-assembling L-form DNA crystal lattice | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*GP*AP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*CP*A)-3'), ... | Authors: | Simmons, C.R, Yan, H. | Deposit date: | 2017-05-24 | Release date: | 2017-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals. J. Am. Chem. Soc., 139, 2017
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6QLM
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![BU of 6qlm by Molmil](/molmil-images/mine/6qlm) | Cathepsin-K in complex with MIV-701 | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Cathepsin K, GLYCEROL, ... | Authors: | Derbyshire, D.J. | Deposit date: | 2019-02-01 | Release date: | 2020-02-19 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
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5VJN
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![BU of 5vjn by Molmil](/molmil-images/mine/5vjn) | Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with D-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (D-DIAB) and Adenine | Descriptor: | 1,2-ETHANEDIOL, ADENINE, Adenine phosphoribosyltransferase 1, ... | Authors: | Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L. | Deposit date: | 2017-04-19 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase. ACS Chem. Biol., 13, 2018
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5VYF
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6QM0
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![BU of 6qm0 by Molmil](/molmil-images/mine/6qm0) | Cathepsin-K in complex with amino-oxaazabicyclo[3.3.0]octanyl containing inhibitor | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Cathepsin K, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-azanyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-3-fluoranyl-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide | Authors: | Derbyshire, D.J. | Deposit date: | 2019-02-01 | Release date: | 2020-02-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
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3HH1
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![BU of 3hh1 by Molmil](/molmil-images/mine/3hh1) | The Structure of a Tetrapyrrole methylase family protein domain from Chlorobium tepidum TLS | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Tetrapyrrole methylase family protein | Authors: | Cuff, M.E, Sather, A, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-05-14 | Release date: | 2009-07-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Structure of a Tetrapyrrole methylase family protein domain from Chlorobium tepidum TLS. TO BE PUBLISHED
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4WAC
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![BU of 4wac by Molmil](/molmil-images/mine/4wac) | Crystal Structure of TarM | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Koc, C, Stehle, T, Xia, G, Peschel, A. | Deposit date: | 2014-08-29 | Release date: | 2015-02-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid. J.Biol.Chem., 290, 2015
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3HI5
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![BU of 3hi5 by Molmil](/molmil-images/mine/3hi5) | Crystal structure of Fab fragment of AL-57 | Descriptor: | Heavy chain of Fab fragment of AL-57 against alpha L I domain, light chain of Fab fragment of AL-57 against alpha L I domain | Authors: | Zhang, H, Wang, J. | Deposit date: | 2009-05-18 | Release date: | 2009-09-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. Proc.Natl.Acad.Sci.USA, 106, 2009
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5VZ7
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![BU of 5vz7 by Molmil](/molmil-images/mine/5vz7) | Pre-catalytic ternary complex of human Polymerase Mu (G433A) mutant with incoming nonhydrolyzable UMPNPP | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | Authors: | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | Deposit date: | 2017-05-27 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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5VZD
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![BU of 5vzd by Molmil](/molmil-images/mine/5vzd) | Pre-catalytic ternary complex of human Polymerase Mu (W434A) mutant with incoming nonhydrolyzable UMPNPP | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | Authors: | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | Deposit date: | 2017-05-27 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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4WDD
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![BU of 4wdd by Molmil](/molmil-images/mine/4wdd) | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A, complexed with citrate | Descriptor: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CHLORIDE ION, CITRIC ACID, ... | Authors: | Myllykoski, M, Raasakka, A, Kursula, P. | Deposit date: | 2014-09-08 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
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5VZL
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![BU of 5vzl by Molmil](/molmil-images/mine/5vzl) | cryo-EM structure of the Cas9-sgRNA-AcrIIA4 anti-CRISPR complex | Descriptor: | CRISPR-associated endonuclease Cas9, phage anti-CRISPR AcrIIA4, single guide RNA (116-MER) | Authors: | Jiang, F, Liu, J.J, Nogales, E, Doudna, J.A. | Deposit date: | 2017-05-29 | Release date: | 2017-07-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Disabling Cas9 by an anti-CRISPR DNA mimic. Sci Adv, 3, 2017
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7LRM
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![BU of 7lrm by Molmil](/molmil-images/mine/7lrm) | Structure of HIV-1 Reverse Transcriptase in complex with DNA, dCTP, and CA(2+) ion | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA/RNA (38-MER), ... | Authors: | Hoang, A, Ruiz, F.X, Arnold, E. | Deposit date: | 2021-02-16 | Release date: | 2022-02-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
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5VM0
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![BU of 5vm0 by Molmil](/molmil-images/mine/5vm0) | The hapten triclocarban bound to the single domain camelid nanobody VHH T9 | Descriptor: | 1,2-ETHANEDIOL, Camelid Nanobody VHH T9, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea | Authors: | Wogulis, L.A, Wogulis, M.D, Tabares-da Rosa, S, Gonzalez-Sapienza, G, Wilson, D.K. | Deposit date: | 2017-04-26 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structure and specificity of several triclocarban-binding single domain camelid antibody fragments. J. Mol. Recognit., 32, 2019
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7R98
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![BU of 7r98 by Molmil](/molmil-images/mine/7r98) | |
5VNE
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3HH7
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![BU of 3hh7 by Molmil](/molmil-images/mine/3hh7) | Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra) | Descriptor: | Muscarinic toxin-like protein 3 homolog | Authors: | Roy, A, Zhou, X, Chong, M.Z, D'hoedt, D, Foo, C.S, Rajagopalan, N, Nirthanan, S, Bertrand, D, Sivaraman, J, Kini, R.M. | Deposit date: | 2009-05-15 | Release date: | 2010-01-12 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra) J.Biol.Chem., 285, 2010
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3HJ6
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![BU of 3hj6 by Molmil](/molmil-images/mine/3hj6) | Structure of Halothermothrix orenii fructokinase (FRK) | Descriptor: | Fructokinase | Authors: | Chua, T.K, Seetharaman, J, Kasprzak, J.M, Ng, C, Patel, B.K, Love, C, Bujnicki, J.M, Sivaraman, J. | Deposit date: | 2009-05-21 | Release date: | 2010-06-09 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a fructokinase homolog from Halothermothrix orenii J.Struct.Biol., 171, 2010
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3HHS
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![BU of 3hhs by Molmil](/molmil-images/mine/3hhs) | Crystal Structure of Manduca sexta prophenoloxidase | Descriptor: | COPPER (II) ION, Phenoloxidase subunit 1, Phenoloxidase subunit 2 | Authors: | Li, Y, Wang, Y, Jiang, H, Deng, J. | Deposit date: | 2009-05-17 | Release date: | 2009-09-29 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes. Proc.Natl.Acad.Sci.USA, 106, 2009
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7LPN
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![BU of 7lpn by Molmil](/molmil-images/mine/7lpn) | |