8FXW

Cryo-EM structure of cowpox virus M2 in complex with human B7.1 (hexameric ring)

Summary for 8FXW

• Entry DOI: 10.2210/pdb8fxw/pdb
• EMDB information: 29546
• Descriptor: CPXV040 protein, T-lymphocyte activation antigen CD80, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: poxvirus m2 protein, opg038, t-cell costimulation, poxviral immune evasion domain pie, b7.1, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• Biological source: Cowpox virus (Brighton Red); More
• Total number of polymer chains: 12
• Total formula weight: 296799.92

Authors

Elliott, J.I.,Adams, L.J.,Nelson, C.A.,Fremont, D.H.,CSBID,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2023-01-25, release date: 2025-02-05, Last modification date: 2025-03-19)

• Primary citation: Elliott, J.I.,Adams, L.J.,Jethva, P.N.,Gross, M.L.,Nelson, C.A.,Fremont, D.H.; Structure basis of poxvirus mediated sabotage of T-cell costimulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)