8VSW
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![BU of 8vsw by Molmil](/molmil-images/mine/8vsw) | 4-MERCAPTOPHENOL-ALPHA3C | Descriptor: | 4-mercaptophenol-alpha3C protein, 4-sulfanylphenol | Authors: | Tommos, C. | Deposit date: | 2024-01-24 | Release date: | 2024-03-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Switching the proton-coupled electron transfer mechanism for non-canonical tyrosine residues in a de novo protein. Chem Sci, 15, 2024
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8VSA
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![BU of 8vsa by Molmil](/molmil-images/mine/8vsa) | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site of E. coli 70S ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Teran, D, Zhang, Y, Korostelev, A.A. | Deposit date: | 2024-01-23 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon. Front Microbiol, 15, 2024
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8VS9
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![BU of 8vs9 by Molmil](/molmil-images/mine/8vs9) | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site and deacyl-tRNA in the E site of E. coli 70S ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Teran, D, Zhang, Y, Korostelev, A.A. | Deposit date: | 2024-01-23 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon. Front Microbiol, 15, 2024
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8Y0W
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![BU of 8y0w by Molmil](/molmil-images/mine/8y0w) | |
8Y0X
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![BU of 8y0x by Molmil](/molmil-images/mine/8y0x) | Dormant ribosome with SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The global structure of dormant ribosome To Be Published
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8Y0U
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![BU of 8y0u by Molmil](/molmil-images/mine/8y0u) | dormant ribosome with STM1 | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | dormant ribosome with STM1 To Be Published
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8RRR
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![BU of 8rrr by Molmil](/molmil-images/mine/8rrr) | Alpha-synuclein amyloid fibril | Descriptor: | Alpha-synuclein | Authors: | Saibil, H.R, Monistrol, J. | Deposit date: | 2024-01-23 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly Biorxiv, 2024
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8VRK
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![BU of 8vrk by Molmil](/molmil-images/mine/8vrk) | |
8VRJ
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![BU of 8vrj by Molmil](/molmil-images/mine/8vrj) | |
8VRD
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![BU of 8vrd by Molmil](/molmil-images/mine/8vrd) | |
8VR3
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![BU of 8vr3 by Molmil](/molmil-images/mine/8vr3) | crystal structure of the Pcryo_0618 aminotransferase from Psychrobacter cryohalolentis K5 in the presence of its internal aldimine | Descriptor: | 1,2-ETHANEDIOL, 2,2'-(1,4-diazepane-1,4-diyl)di(ethane-1-sulfonic acid), CHLORIDE ION, ... | Authors: | Bockhaus, N.J, Thoden, J.B, Holden, H.M. | Deposit date: | 2024-01-20 | Release date: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published
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8XYB
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![BU of 8xyb by Molmil](/molmil-images/mine/8xyb) | hPhK gamma-delta subcomplex in inactive state | Descriptor: | Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ... | Authors: | Yang, X.K, Xiao, J.Y. | Deposit date: | 2024-01-19 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
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8XYA
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8XXL
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![BU of 8xxl by Molmil](/molmil-images/mine/8xxl) | Cryo-EM structure of the human 40S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXM
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![BU of 8xxm by Molmil](/molmil-images/mine/8xxm) | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXN
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![BU of 8xxn by Molmil](/molmil-images/mine/8xxn) | Cryo-EM structure of the human 43S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8RQM
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![BU of 8rqm by Molmil](/molmil-images/mine/8rqm) | Alpha-synuclein amyloid fibrils | Descriptor: | Alpha-synuclein | Authors: | Saibil, H.R, Monistrol, J. | Deposit date: | 2024-01-18 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly Biorxiv, 2024
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8RPZ
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![BU of 8rpz by Molmil](/molmil-images/mine/8rpz) | Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation I | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... | Authors: | Lauer, S, Nikolay, R, Spahn, C. | Deposit date: | 2024-01-17 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
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8RPY
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![BU of 8rpy by Molmil](/molmil-images/mine/8rpy) | Escherichia coli 50S subunit in complex with the antimicrobial peptide Api137 | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 137, ... | Authors: | Lauer, S, Nikolay, R, Spahn, C. | Deposit date: | 2024-01-17 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
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8RQ0
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![BU of 8rq0 by Molmil](/molmil-images/mine/8rq0) | Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation II | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... | Authors: | Lauer, S, Nikolay, R, Spahn, C. | Deposit date: | 2024-01-17 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
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8VQ4
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![BU of 8vq4 by Molmil](/molmil-images/mine/8vq4) | CDK2-CyclinE1 in complex with allosteric inhibitor I-125A. | Descriptor: | (8R)-6-(1-benzyl-1H-pyrazole-4-carbonyl)-N-[(2S,3R)-3-(2-cyclohexylethoxy)-1-(methylamino)-1-oxobutan-2-yl]-2-[(1S)-2,2-dimethylcyclopropane-1-carbonyl]-2,6-diazaspiro[3.4]octane-8-carboxamide, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Hirschi, M, Johnson, E, Zhang, Y, Liu, Z, Brodsky, O, Won, S.J, Nagata, A, Petroski, M.D, Majmudar, J.D, Niessen, S, VanArsdale, T, Gilbert, A.M, Hayward, M.M, Stewart, A.E, Nager, A.R, Melillo, B, Cravatt, B. | Deposit date: | 2024-01-17 | Release date: | 2024-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Expanding the ligandable proteome by paralog hopping with covalent probes. Biorxiv, 2024
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8VQ3
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![BU of 8vq3 by Molmil](/molmil-images/mine/8vq3) | CDK2-CyclinE1 in complex with allosteric inhibitor I-198. | Descriptor: | (8R)-N-[(2S,3R)-3-(cyclohexylmethoxy)-1-(morpholin-4-yl)-1-oxobutan-2-yl]-2-[(1S)-2,2-dimethylcyclopropane-1-carbonyl]-6-(1,3-thiazole-5-carbonyl)-2,6-diazaspiro[3.4]octane-8-carboxamide, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Hirschi, M, Johnson, E, Zhang, Y, Liu, Z, Brodsky, O, Won, S.J, Nagata, A, Petroski, M.D, Majmudar, J.D, Niessen, S, VanArsdale, T, Gilbert, A.M, Hayward, M.M, Stewart, A.E, Nager, A.R, Melillo, B, Cravatt, B. | Deposit date: | 2024-01-17 | Release date: | 2024-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Expanding the ligandable proteome by paralog hopping with covalent probes. Biorxiv, 2024
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8RQ2
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![BU of 8rq2 by Molmil](/molmil-images/mine/8rq2) | Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation III | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... | Authors: | Lauer, S, Nikolay, R, Spahn, C. | Deposit date: | 2024-01-17 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
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8VOV
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![BU of 8vov by Molmil](/molmil-images/mine/8vov) | Structure of VCP in complex with an ATPase activator and ADP (D2 domains only, hexameric form) | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | Deposit date: | 2024-01-16 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8XW0
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![BU of 8xw0 by Molmil](/molmil-images/mine/8xw0) | Cryo-EM structure of OSCA3.1-GDN state | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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