8RPY

Escherichia coli 50S subunit in complex with the antimicrobial peptide Api137

Summary for 8RPY

• Entry DOI: 10.2210/pdb8rpy/pdb
• EMDB information: 19426
• Descriptor: Large ribosomal subunit protein bL32, Large ribosomal subunit protein uL3, Large ribosomal subunit protein uL4, ... (32 entities in total)
• Functional Keywords: ribosome, antimicrobial peptide, rna, ribosomal protein, pramp, proline-rich peptide, antibiotics, 50s, api137
• Biological source: Escherichia coli; More
• Total number of polymer chains: 33
• Total formula weight: 1349111.71

Authors

Lauer, S.,Nikolay, R.,Spahn, C. (deposition date: 2024-01-17, release date: 2024-05-22)

• Primary citation: Lauer, S.M.,Reepmeyer, M.,Berendes, O.,Klepacki, D.,Gasse, J.,Gabrielli, S.,Grubmuller, H.,Bock, L.V.,Krizsan, A.,Nikolay, R.,Spahn, C.M.T.,Hoffmann, R.; Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88.; Nat Commun, 15:3945-3945, 2024; PubMed: 38730238; DOI: 10.1038/s41467-024-48027-4

Experimental method

ELECTRON MICROSCOPY (2.64 Å)