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8QU2
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BU of 8qu2 by Molmil
NF-YB/C Heterodimer in Complex with a 16-mer NF-YA-derived Peptide Stabilized with C8-Hydrocarbon Linker
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, ...
Authors:Durukan, C, Arbore, F, Klintrot, C.I.R, Grossmann, T.N, Hennig, S.
Deposit date:2023-10-13
Release date:2024-03-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Binding Dynamics of a Stapled Peptide Targeting the Transcription Factor NF-Y.
Chembiochem, 25, 2024
7U0J
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BU of 7u0j by Molmil
Structure of 162bp LIN28b nucleosome
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U46
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BU of 7u46 by Molmil
Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7U47
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BU of 7u47 by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and palindromic alpha satellite DNA sequence
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7SCZ
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BU of 7scz by Molmil
Nuc147 bound to multiple BRCTs
Descriptor: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ...
Authors:Muthurajan, U.M, Rudolph, J.
Deposit date:2021-09-29
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
8PEP
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BU of 8pep by Molmil
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-14
Release date:2023-08-16
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8OX0
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BU of 8ox0 by Molmil
Structure of apo telomeric nucleosome
Descriptor: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
Authors:Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
Deposit date:2023-04-28
Release date:2023-08-30
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
7U4D
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BU of 7u4d by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and 601 DNA sequence
Descriptor: Centromere protein N, DNA (147-MER), Histone H2A, ...
Authors:Zhou, K, Luger, K.
Deposit date:2022-02-28
Release date:2022-03-30
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7SCY
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BU of 7scy by Molmil
Nuc147 bound to single BRCT
Descriptor: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ...
Authors:Muthurajan, U.M, Rudolph, J.R.
Deposit date:2021-09-29
Release date:2022-01-12
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
8QZM
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BU of 8qzm by Molmil
Structure of DNMT3A1 UDR region bound to H2AK119ub nucleosome
Descriptor: DNA (145-MER), DNA (cytosine-5)-methyltransferase 3A, Histone H2A type 1, ...
Authors:Burdett, H, Wapenaar, H, Wilson, M.D.
Deposit date:2023-10-27
Release date:2024-10-23
Last modified:2024-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment.
Embo Rep., 25, 2024
7SWY
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BU of 7swy by Molmil
2.6 A structure of a 40-601[TA-rich+1]-40 nucleosome
Descriptor: DNA Guide Strand, DNA Tracking Strand, Histone H2A, ...
Authors:Nodelman, I.M, Bowman, G.D, Armache, J.-P.
Deposit date:2021-11-21
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
7T7T
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BU of 7t7t by Molmil
Structure of TSK/BRU1 bound to histone H3.1
Descriptor: Histone H3.1, Protein TONSOKU
Authors:Davarinejad, H, Couture, J.F.
Deposit date:2021-12-15
Release date:2022-03-30
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Science, 375, 2022
7U51
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BU of 7u51 by Molmil
Nucleosome core particle with AP-site at SHL-6
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7U52
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BU of 7u52 by Molmil
nucleosome core particle with AP-site at SHL-6.5
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7U50
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BU of 7u50 by Molmil
APE1 bound to a nucleosome core particle with AP-site at SHL-6
Descriptor: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
Authors:Weaver, T.M, Freudenthal, B.D.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7U53
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BU of 7u53 by Molmil
Nucleosome core particle with AP-site at SHL0
Descriptor: DNA (144-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7UD5
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BU of 7ud5 by Molmil
Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome
Descriptor: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
Deposit date:2022-03-18
Release date:2022-09-21
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UNK
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BU of 7unk by Molmil
Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex
Descriptor: Histone H3, Histone H4, Histone chaperone, ...
Authors:Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y.
Deposit date:2022-04-11
Release date:2022-09-21
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
3A6N
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BU of 3a6n by Molmil
The nucleosome containing a testis-specific histone variant, human H3T
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H.
Deposit date:2009-09-04
Release date:2010-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Proc.Natl.Acad.Sci.USA, 107, 2010
3AYW
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BU of 3ayw by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2011-05-19
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZI
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BU of 3azi by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2011-05-25
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZN
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BU of 3azn by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2011-05-25
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZM
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BU of 3azm by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2011-05-25
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZH
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BU of 3azh by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation
Descriptor: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2011-05-25
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AV1
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BU of 3av1 by Molmil
The human nucleosome structure containing the histone variant H3.2
Descriptor: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011

238582

数据于2025-07-09公开中

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