Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7TOQ
DownloadVisualize
BU of 7toq by Molmil
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7TGR
DownloadVisualize
BU of 7tgr by Molmil
Structure of SARS-CoV-2 main protease in complex with GC376
Descriptor: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ...
Authors:Esler, M.A, Shi, K, Aihara, H, Harris, R.S.
Deposit date:2022-01-09
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells.
Mbio, 13, 2022
7SYX
DownloadVisualize
BU of 7syx by Molmil
Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYW
DownloadVisualize
BU of 7syw by Molmil
Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYV
DownloadVisualize
BU of 7syv by Molmil
Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-20
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYU
DownloadVisualize
BU of 7syu by Molmil
Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYT
DownloadVisualize
BU of 7syt by Molmil
Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYS
DownloadVisualize
BU of 7sys by Molmil
Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII).
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYR
DownloadVisualize
BU of 7syr by Molmil
Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt).
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYQ
DownloadVisualize
BU of 7syq by Molmil
Structure of the wt IRES and 40S ribosome ternary complex, open conformation. Structure 11(wt)
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYP
DownloadVisualize
BU of 7syp by Molmil
Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt)
Descriptor: 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYO
DownloadVisualize
BU of 7syo by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYN
DownloadVisualize
BU of 7syn by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYM
DownloadVisualize
BU of 7sym by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway
To Be Published
7SYL
DownloadVisualize
BU of 7syl by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYK
DownloadVisualize
BU of 7syk by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYJ
DownloadVisualize
BU of 7syj by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYI
DownloadVisualize
BU of 7syi by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYH
DownloadVisualize
BU of 7syh by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYG
DownloadVisualize
BU of 7syg by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SX4
DownloadVisualize
BU of 7sx4 by Molmil
Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 2/2
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kschonsak, M, Chua, H.C, Weidling, C, Chakouri, N, Noland, C.L, Schott, K, Chang, T, Tam, C, Patel, N, Arthur, C.P, Leitner, A, Ben-Johny, M, Ciferri, C, Pless, S.A, Payandeh, J.
Deposit date:2021-11-22
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural architecture of the human NALCN channelosome.
Nature, 603, 2022
7SX3
DownloadVisualize
BU of 7sx3 by Molmil
Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 1/2
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kschonsak, M, Chua, H.C, Weidling, C, Chakouri, N, Noland, C.L, Schott, K, Chang, T, Tam, C, Patel, N, Arthur, C.P, Leitner, A, Ben-Johny, M, Ciferri, C, Pless, S.A, Payandeh, J.
Deposit date:2021-11-22
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural architecture of the human NALCN channelosome.
Nature, 603, 2022
7SUK
DownloadVisualize
BU of 7suk by Molmil
Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells
Descriptor: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ...
Authors:Rai, J, Zhao, Y, Li, H.
Deposit date:2021-11-17
Release date:2022-07-06
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome.
Commun Biol, 5, 2022
7SSZ
DownloadVisualize
BU of 7ssz by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies
Descriptor: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSY
DownloadVisualize
BU of 7ssy by Molmil
Structure of human Kv1.3 (alternate conformation)
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022

221716

数据于2024-06-26公开中

PDB statisticsPDBj update infoContact PDBjnumon