7SX3

Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 1/2

Summary for 7SX3

Entry DOI	10.2210/pdb7sx3/pdb
EMDB information	25492
Descriptor	Sodium leak channel non-selective protein,Enhanced green fluorescent protein, Transmembrane protein FAM155A, Calmodulin-1, ... (9 entities in total)
Functional Keywords	ion channel, calmodulin, heat repeat protein, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	963152.53
Authors	Kschonsak, M.,Chua, H.C.,Weidling, C.,Chakouri, N.,Noland, C.L.,Schott, K.,Chang, T.,Tam, C.,Patel, N.,Arthur, C.P.,Leitner, A.,Ben-Johny, M.,Ciferri, C.,Pless, S.A.,Payandeh, J. (deposition date: 2021-11-22, release date: 2021-12-29, Last modification date: 2022-03-16)
Primary citation	Kschonsak, M.,Chua, H.C.,Weidling, C.,Chakouri, N.,Noland, C.L.,Schott, K.,Chang, T.,Tam, C.,Patel, N.,Arthur, C.P.,Leitner, A.,Ben-Johny, M.,Ciferri, C.,Pless, S.A.,Payandeh, J. Structural architecture of the human NALCN channelosome. Nature, 603:180-186, 2022 Cited by PubMed: 34929720 DOI: 10.1038/s41586-021-04313-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation