7T6U
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![BU of 7t6u by Molmil](/molmil-images/mine/7t6u) | Structure of the human FPR2-Gi complex with CGEN-855A | Descriptor: | B9-scFv, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhuang, Y.W. | Deposit date: | 2021-12-14 | Release date: | 2022-03-30 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2. Nat Commun, 13, 2022
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7SQO
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![BU of 7sqo by Molmil](/molmil-images/mine/7sqo) | Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | McGrath, A.P, Kang, Y, Flinspach, M. | Deposit date: | 2021-11-05 | Release date: | 2022-05-25 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
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7SR8
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![BU of 7sr8 by Molmil](/molmil-images/mine/7sr8) | Molecular mechanism of the the wake-promoting agent TAK-925 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hypocretin receptor type 2, ... | Authors: | Yin, J, Chapman, K, Lian, P, De Brabander, J.K, Rosenbaum, D.M. | Deposit date: | 2021-11-08 | Release date: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
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7TDZ
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![BU of 7tdz by Molmil](/molmil-images/mine/7tdz) | |
5IKD
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5IKG
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1C7H
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![BU of 1c7h by Molmil](/molmil-images/mine/1c7h) | CRYSTAL STRUCTURE OF A MUTANT R75A IN KETOSTEROID ISOMERASE FROM PSEDOMONAS PUTIDA BIOTYPE B | Descriptor: | DELTA-5-3-KETOSTEROID ISOMERASE | Authors: | Nam, G.H, Kim, D.H, Jang, D.S, Choi, G, Ha, N.C, Oh, B.H, Choi, K.Y. | Deposit date: | 2000-02-19 | Release date: | 2000-04-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B. Biochemistry, 38, 1999
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6W17
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![BU of 6w17 by Molmil](/molmil-images/mine/6w17) | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Shaaban, M, Nolen, B.J, Chowdhury, S. | Deposit date: | 2020-03-03 | Release date: | 2020-08-12 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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6PTZ
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![BU of 6ptz by Molmil](/molmil-images/mine/6ptz) | Crystal structure of pigeon Cryptochrome 4 mutant Y319D in complex with flavin adenine dinucleotide | Descriptor: | Cryptochrome-1, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zoltowski, B.D, Chelliah, Y, Wickramaratne, A.C, Jarocha, L, Karki, N, Mouritsen, H, Hore, P.J, Hibbs, R.E, Green, C.B, Takahashi, J.S. | Deposit date: | 2019-07-16 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.793 Å) | Cite: | Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon. Proc.Natl.Acad.Sci.USA, 116, 2019
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6PU0
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![BU of 6pu0 by Molmil](/molmil-images/mine/6pu0) | Pigeon Cryptochrome4 bound to flavin adenine dinucleotide | Descriptor: | 1,2-ETHANEDIOL, Cryptochrome-1, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zoltowski, B.D, Chelliah, Y, Wickramaratne, A.C, Jarocha, L, Karki, N, Mouritsen, H, Hore, P.J, Hibbs, R.E, Green, C.B, Takahashi, J.S. | Deposit date: | 2019-07-16 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8979 Å) | Cite: | Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon. Proc.Natl.Acad.Sci.USA, 116, 2019
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3ORV
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4JFA
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![BU of 4jfa by Molmil](/molmil-images/mine/4jfa) | Crystal Structure of Plasmodium falciparum Tryptophanyl-tRNA synthetase | Descriptor: | BETA-MERCAPTOETHANOL, POTASSIUM ION, TRYPTOPHAN, ... | Authors: | Khan, S, Garg, A, Manickam, Y, Sharma, A. | Deposit date: | 2013-02-28 | Release date: | 2014-01-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An appended domain results in an unusual architecture for malaria parasite tryptophanyl-tRNA synthetase Plos One, 8, 2013
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1MAF
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4FNI
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8CJD
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![BU of 8cjd by Molmil](/molmil-images/mine/8cjd) | AetF, a single-component flavin-dependent tryptophan halogenase | Descriptor: | 1,2-ETHANEDIOL, AetF, CALCIUM ION, ... | Authors: | Gafe, S, Niemann, H.H. | Deposit date: | 2023-02-13 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of regioselective tryptophan dibromination by the single-component flavin-dependent halogenase AetF. Acta Crystallogr D Struct Biol, 79, 2023
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4B3N
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![BU of 4b3n by Molmil](/molmil-images/mine/4b3n) | Crystal structure of rhesus TRIM5alpha PRY/SPRY domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ... | Authors: | Yang, H, Ji, X, Zhao, Q, Xiong, Y. | Deposit date: | 2012-07-25 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha Proc.Natl.Acad.Sci.USA, 109, 2012
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4FNH
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![BU of 4fnh by Molmil](/molmil-images/mine/4fnh) | Crystal structure of IsdI-W66Y in complex with heme | Descriptor: | Heme-degrading monooxygenase isdI, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ukpabi, G.N, Murphy, M.E.P. | Deposit date: | 2012-06-19 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Inactivation of the heme degrading enzyme IsdI by an active site substitution that diminishes heme ruffling. J.Biol.Chem., 287, 2012
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1MAE
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1JA0
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![BU of 1ja0 by Molmil](/molmil-images/mine/1ja0) | CYPOR-W677X | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | Deposit date: | 2001-05-29 | Release date: | 2001-08-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J.Biol.Chem., 276, 2001
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1J9Z
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![BU of 1j9z by Molmil](/molmil-images/mine/1j9z) | CYPOR-W677G | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | Deposit date: | 2001-05-29 | Release date: | 2001-08-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J.Biol.Chem., 276, 2001
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3CCP
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![BU of 3ccp by Molmil](/molmil-images/mine/3ccp) | X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE | Authors: | Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J. | Deposit date: | 1990-02-28 | Release date: | 1991-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis. Biochemistry, 29, 1990
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3BP2
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3SVW
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3SJL
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3WE0
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![BU of 3we0 by Molmil](/molmil-images/mine/3we0) | L-Amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase/monooxygenase | Authors: | Im, D.H, Matsui, D, Fukuta, Y, Fushinobu, S, Isobe, K, Asano, Y. | Deposit date: | 2013-06-26 | Release date: | 2014-02-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities FEBS Open Bio, 4, 2014
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