7NHA
 
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-10 | | Release date: | 2021-12-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NHC
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-10 | | Release date: | 2021-12-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NI0
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-11 | | Release date: | 2021-12-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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4PN1
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6F42
 | | RNA Polymerase III closed complex CC1. | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
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6F41
 | | RNA Polymerase III initially transcribing complex | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
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6EU1
 | | RNA Polymerase III - open DNA complex (OC-POL3). | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. | | Deposit date: | 2017-10-27 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
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6F40
 | | RNA Polymerase III open complex | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
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8RC4
 | | Structure of Integrator-PP2A complex | | Descriptor: | DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-06 | | Release date: | 2024-02-07 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 629, 2024
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4YM7
 | | RNA polymerase I structure with an alternative dimer hinge | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P. | | Deposit date: | 2015-03-06 | | Release date: | 2015-09-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (5.5 Å) | | Cite: | An alternative RNA polymerase I structure reveals a dimer hinge.
Acta Crystallogr.,Sect.D, 71, 2015
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5M64
 | | RNA Polymerase I elongation complex with A49 tandem winged helix domain | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-24 | | Release date: | 2016-12-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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5M5W
 | | RNA Polymerase I open complex | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-23 | | Release date: | 2016-12-07 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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5M5Y
 | | RNA Polymerase I elongation complex 2 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-23 | | Release date: | 2016-12-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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5M5X
 | | RNA Polymerase I elongation complex 1 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-23 | | Release date: | 2016-12-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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6RQT
 | | RNA Polymerase I-tWH-Rrn3-DNA | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-16 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6RUI
 | | RNA Polymerase I Pre-initiation complex DNA opening intermediate 2 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-28 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6RQH
 | | RNA Polymerase I Closed Conformation 1 (CC1) | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-15 | | Release date: | 2019-12-11 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6RWE
 | | RNA Polymerase I Open Complex conformation 2 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-06-04 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6RRD
 | | RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-17 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6RUO
 | | RNA Polymerase I Open Complex conformation 1 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-28 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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8TVY
 | | Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | Deposit date: | 2023-08-18 | | Release date: | 2024-01-24 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6RQL
 | | RNA Polymerase I Closed Conformation 2 (CC2) | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | | Deposit date: | 2019-05-16 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6EU0
 | | RNA Polymerase III open pre-initiation complex (OC-PIC) | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. | | Deposit date: | 2017-10-27 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
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6F44
 | | RNA Polymerase III closed complex CC2. | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Molecular mechanism of promoter opening by RNA polymerase III.
Nature, 553, 2018
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2B63
 | | Complete RNA Polymerase II-RNA inhibitor complex | | Descriptor: | 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | | Authors: | Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P. | | Deposit date: | 2005-09-30 | | Release date: | 2005-12-06 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Nat.Struct.Mol.Biol., 13, 2006
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