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7W54
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BU of 7w54 by Molmil
Crystal structure of a bacterial OTU DUB with Ub-PA
Descriptor: Lpg2248, Polyubiquitin-B, prop-2-en-1-amine
Authors:Zhen, X, Ouyang, S.Y.
Deposit date:2021-11-29
Release date:2022-08-24
Last modified:2023-04-05
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA.
J.Biol.Chem., 298, 2022
7W3U
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BU of 7w3u by Molmil
USP34 catalytic domain in complex with UbPA
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 34, ZINC ION, ...
Authors:Xu, G.L, Ming, Z.H.
Deposit date:2021-11-26
Release date:2022-06-01
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural Insights into the Catalytic Mechanism and Ubiquitin Recognition of USP34.
J.Mol.Biol., 434, 2022
7W3H
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BU of 7w3h by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W39
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BU of 7w39 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.1_UBL
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3B
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BU of 7w3b by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3G
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BU of 7w3g by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3J
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BU of 7w3j by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3C
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BU of 7w3c by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3A
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BU of 7w3a by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3F
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BU of 7w3f by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W38
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BU of 7w38 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.0_UBL
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3K
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BU of 7w3k by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3M
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BU of 7w3m by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-18
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W3I
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BU of 7w3i by Molmil
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-18
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7SYN
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BU of 7syn by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYJ
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BU of 7syj by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYL
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BU of 7syl by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYX
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BU of 7syx by Molmil
Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYW
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BU of 7syw by Molmil
Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYG
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BU of 7syg by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYI
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BU of 7syi by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYM
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BU of 7sym by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway
To Be Published
7SYU
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BU of 7syu by Molmil
Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYK
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BU of 7syk by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYT
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BU of 7syt by Molmil
Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022

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数据于2024-06-26公开中

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