5XJC
 
 | | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | | Deposit date: | 2017-04-30 | | Release date: | 2017-07-05 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
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7O4J
 | | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-06 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O4I
 | | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-06 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7NZM
 | | Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Yan, Y, Hardwick, S, Ron, D. | | Deposit date: | 2021-03-24 | | Release date: | 2021-09-29 | | Last modified: | 2021-10-20 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Nat.Struct.Mol.Biol., 28, 2021
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5YLZ
 | | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | | Deposit date: | 2017-10-20 | | Release date: | 2018-07-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
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5YJJ
 | | Crystal structure of PNPase from Staphylococcus epidermidis | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Polyribonucleotide nucleotidyltransferase | | Authors: | Raj, R, Gopal, B. | | Deposit date: | 2017-10-10 | | Release date: | 2018-01-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Characterization of Staphylococcus epidermidis Polynucleotide phosphorylase and its interactions with ribonucleases RNase J1 and RNase J2.
Biochem. Biophys. Res. Commun., 495, 2018
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7OQY
 | | Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-04 | | Release date: | 2021-08-25 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OQ4
 | | Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-02 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OOP
 | | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-28 | | Release date: | 2021-10-06 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7OPD
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-06 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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7OPC
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-13 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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4AIM
 | | Crystal structure of C. crescentus PNPase bound to RNase E recognition peptide | | Descriptor: | PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RIBONUCLEASE, ... | | Authors: | Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F. | | Deposit date: | 2012-02-10 | | Release date: | 2012-04-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Open Biol., 2, 2012
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5WLC
 | | The complete structure of the small subunit processome | | Descriptor: | 18S pre-rRNA, 5' ETS, Bms1, ... | | Authors: | Barandun, J, Chaker-Margot, M, Hunziker, M, Klinge, S. | | Deposit date: | 2017-07-26 | | Release date: | 2017-09-27 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The complete structure of the small-subunit processome.
Nat. Struct. Mol. Biol., 24, 2017
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4A3F
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP | | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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5WYJ
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | Authors: | Ye, K, Zhu, X, Sun, Q. | | Deposit date: | 2017-01-13 | | Release date: | 2017-03-29 | | Last modified: | 2019-10-09 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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4A3E
 | | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP | | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3L
 | | RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP | | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3M
 | | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP | | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4AM3
 | | Crystal structure of C. crescentus PNPase bound to RNA | | Descriptor: | PHOSPHATE ION, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE, RNA, ... | | Authors: | Hardwick, S.W, Gubbey, T, Hug, I, Jenal, U, Luisi, B.F. | | Deposit date: | 2012-03-07 | | Release date: | 2012-04-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Open Biol., 2, 2012
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4A3C
 | | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-11-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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5XOG
 | | RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1 | | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (30-MER), DNA (39-MER), ... | | Authors: | Ehara, H, Shirouzu, M, Sekine, S. | | Deposit date: | 2017-05-28 | | Release date: | 2017-08-16 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the complete elongation complex of RNA polymerase II with basal factors
Science, 357, 2017
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4A3D
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3K
 | | RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid | | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
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4A3G
 | | RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2012-02-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4AYB
 | | RNAP at 3.2Ang | | Descriptor: | DNA-DIRECTED RNA POLYMERASE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A. | | Deposit date: | 2012-06-19 | | Release date: | 2012-08-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.202 Å) | | Cite: | Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
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