6F1U
 
 | | N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... | | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | Deposit date: | 2017-11-23 | | Release date: | 2018-01-17 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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6F38
 | | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | Authors: | Lau, C.K, Urnavicius, L, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | Deposit date: | 2017-11-28 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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8P94
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6FHS
 | | CryoEM Structure of INO80core | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Arp5, ... | | Authors: | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | | Deposit date: | 2018-01-15 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.754 Å) | | Cite: | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
Nature, 556, 2018
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6FM2
 | | CARP domain of mouse cyclase-associated protein 1 (CAP1) bound to ADP-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Kotila, T.M, Kogan, K, Lappalainen, P. | | Deposit date: | 2018-01-30 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis of actin monomer re-charging by cyclase-associated protein.
Nat Commun, 9, 2018
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6G2T
 | | human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament | | Descriptor: | Actin, cytoplasmic 2, Myosin-binding protein C, ... | | Authors: | Risi, C, Belknap, B, Forgacs, E, Harris, S.P, Schroder, G.F, White, H.D, Galkin, V.E. | | Deposit date: | 2018-03-23 | | Release date: | 2018-10-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.
Structure, 26, 2018
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8PTK
 | | Composite structure of Dynein-Dynactin-JIP3-LIS1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PR4
 | | Dynactin pointed end bound to JIP3 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Arp11, C-Jun-amino-terminal kinase-interacting protein 3, ... | | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | Deposit date: | 2023-07-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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6FML
 | | CryoEM Structure INO80core Nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin related protein 5, ... | | Authors: | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | | Deposit date: | 2018-01-31 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.34 Å) | | Cite: | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
Nature, 556, 2018
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6GEJ
 | | Chromatin remodeller-nucleosome complex at 3.6 A resolution. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | Deposit date: | 2018-04-26 | | Release date: | 2018-10-17 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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8QR1
 | | Cryo-EM structure of the human Tip60 complex | | Descriptor: | Actin, cytoplasmic 1, N-terminally processed, ... | | Authors: | Li, C, Smirnova, E, Schnitzler, C, Crucifix, C, Concordet, J.P, Brion, A, Poterszman, A, Schultz, P, Papai, G, Ben-Shem, A. | | Deposit date: | 2023-10-06 | | Release date: | 2024-08-07 | | Last modified: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structure of the human TIP60-C histone exchange and acetyltransferase complex.
Nature, 635, 2024
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6GVC
 | | Structure of ArhGAP12 bound to G-Actin | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Mouilleron, S, Treisman, R, Diring, J. | | Deposit date: | 2018-06-20 | | Release date: | 2019-03-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.
Nat.Cell Biol., 21, 2019
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8QKV
 | | SWR1-nucleosome complex in configuration 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Jalal, A.S.B, Wigley, D.B. | | Deposit date: | 2023-09-18 | | Release date: | 2024-10-02 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Nucleosome flipping drives kinetic proofreading and processivity by SWR1.
Nature, 636, 2024
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8QYV
 | | SWR1-hexasome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Jalal, A.S.B, Wigley, D.B. | | Deposit date: | 2023-10-26 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complex.
Mol.Cell, 84, 2024
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1RGI
 | | Crystal structure of gelsolin domains G1-G3 bound to actin | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Burtnick, L.D, Urosev, D, Irobi, E, Narayan, K, Robinson, R.C. | | Deposit date: | 2003-11-12 | | Release date: | 2004-07-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF
Embo J., 23, 2004
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8Q4G
 | | Thin filament from FIB milled relaxed left ventricular mouse myofibrils | | Descriptor: | Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain | | Authors: | Tamborrini, D, Wang, Z, Wagner, T, Tacke, S, Stabrin, M, Grange, M, Kho, A.L, Bennet, P, Rees, M, Gautel, M, Raunser, S. | | Deposit date: | 2023-08-06 | | Release date: | 2023-11-01 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Structure of the native myosin filament in the relaxed cardiac sarcomere.
Nature, 623, 2023
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8R9V
 | | CryoEM structure of the primed actomyosin-5a complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Klebl, D.P, McMillan, S.N, Risi, C, Forgacs, E, Virok, B, Atherton, J.L, Stofella, M, Winkelmann, D.A, Sobott, F, Galkin, V.E, Knight, P.J, Muench, S.P, Scarff, C.A, White, H.D. | | Deposit date: | 2023-11-30 | | Release date: | 2024-12-11 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM.
Nature, 642, 2025
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1T44
 | | Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha, ... | | Authors: | Irobi, E, Aguda, A.H, Larsson, M, Burtnick, L.D, Robinson, R.C. | | Deposit date: | 2004-04-28 | | Release date: | 2004-09-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins.
Embo J., 23, 2004
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1SQK
 | | CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F. | | Deposit date: | 2004-03-19 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly
Cell(Cambridge,Mass.), 117, 2004
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1TYQ
 | | Crystal structure of Arp2/3 complex with bound ATP and calcium | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related Protein 2, Actin-related protein 3, ... | | Authors: | Nolen, B.J, Littlefield, R.S, Pollard, T.D. | | Deposit date: | 2004-07-08 | | Release date: | 2004-11-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
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8RX1
 | | CryoEM structure of the gTuRC-CM1dim complex | | Descriptor: | Actin b, CM1, Gamma-tubulin complex component 2, ... | | Authors: | Llorca, O, Serna, M, Gonzalez-Rodriguez, N. | | Deposit date: | 2024-02-06 | | Release date: | 2024-09-25 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | CDK5RAP2 activates microtubule nucleator gamma TuRC by facilitating template formation and actin release.
Dev.Cell, 59, 2024
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8RBF
 | | CryoEM structure of the post-powerstroke actomyosin-5a complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Klebl, D.P, McMillan, S.N, Risi, C, Forgacs, E, Virok, B, Atherton, J.L, Stofella, M, Winkelmann, D.A, Sobott, F, Galkin, V.E, Knight, P.J, Muench, S.P, Scarff, C.A, White, H.D. | | Deposit date: | 2023-12-04 | | Release date: | 2024-12-11 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM.
Nature, 642, 2025
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5YEE
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8SYF
 | | Homology model of Acto-HMM complex in ADP-state. Chicken smooth muscle HMM and chicken pectoralis actin | | Descriptor: | Actin, alpha skeletal muscle, Myosin light polypeptide 6, ... | | Authors: | Hojjatian, A, Taylor, D.W, Daneshparvar, N, Trybus, K.M, Taylor, K.A. | | Deposit date: | 2023-05-25 | | Release date: | 2023-08-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (19 Å) | | Cite: | Double-headed binding of myosin II to F-actin shows the effect of strain on head structure.
J.Struct.Biol., 215, 2023
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5YPU
 | | Crystal structure of an actin monomer in complex with the nucleator Cordon-Bleu MET72NLE WH2-motif peptide | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Scipion, C.P.M, Wongsantichon, J, Ferrer, F.J, Yuen, T.Y, Robinson, R.C. | | Deposit date: | 2017-11-03 | | Release date: | 2018-09-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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