6GVC

Structure of ArhGAP12 bound to G-Actin

Summary for 6GVC

Entry DOI	10.2210/pdb6gvc/pdb
Descriptor	Actin, alpha skeletal muscle, Rho GTPase-activating protein 12, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	gap, rac, actin, hydrolase
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	8
Total formula weight	279271.90
Authors	Mouilleron, S.,Treisman, R.,Diring, J. (deposition date: 2018-06-20, release date: 2019-03-27, Last modification date: 2024-01-17)
Primary citation	Diring, J.,Mouilleron, S.,McDonald, N.Q.,Treisman, R. RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability. Nat.Cell Biol., 21:845-855, 2019 Cited by PubMed: 31209295 DOI: 10.1038/s41556-019-0337-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation