6G2T
human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament
Summary for 6G2T
Entry DOI | 10.2210/pdb6g2t/pdb |
EMDB information | 4346 |
Descriptor | Actin, cytoplasmic 2, Myosin-binding protein C, cardiac-type, Tropomyosin (3 entities in total) |
Functional Keywords | cardiac thin filament regulator, contractile protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 16 |
Total formula weight | 370146.14 |
Authors | Risi, C.,Belknap, B.,Forgacs, E.,Harris, S.P.,Schroder, G.F.,White, H.D.,Galkin, V.E. (deposition date: 2018-03-23, release date: 2018-10-17, Last modification date: 2018-12-19) |
Primary citation | Risi, C.,Belknap, B.,Forgacs-Lonart, E.,Harris, S.P.,Schroder, G.F.,White, H.D.,Galkin, V.E. N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament. Structure, 26:1604-1611.e4, 2018 Cited by PubMed: 30270174DOI: 10.1016/j.str.2018.08.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9 Å) |
Structure validation
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