PDB: 46006 resultsInfo pagesStatus searchChemie searchBIRD

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7Z43	Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Cusack, S, Drncova, P. Deposit date: 2022-03-03 Release date: 2022-05-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.123 Å) Cite: Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022
6BRH	The SAM domain of mouse SAMHD1 is critical for its activation and regulation Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION Authors: Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y. Deposit date: 2017-11-30 Release date: 2018-02-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.4 Å) Cite: The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun, 9, 2018
6BRK	The SAM domain of mouse SAMHD1 is critical for its activation and regulation Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION Authors: Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y. Deposit date: 2017-11-30 Release date: 2018-02-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.5 Å) Cite: The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun, 9, 2018
2YFD	STRUCTURAL AND FUNCTIONAL INSIGHTS OF DR2231 PROTEIN, THE MAZG-LIKE NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE FROM DEINOCOCCUS RADIODURANS, COMPLEXED WITH Mg and dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ACETATE ION, CHLORIDE ION, ... Authors: Goncalves, A.M.D, De Sanctis, D, Mcsweeney, S.M. Deposit date: 2011-04-05 Release date: 2011-07-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.767 Å) Cite: Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
3HKN	Human carbonic anhydrase II in complex with (2,3,4,6-Tetra-O-acetyl-beta-D-galactopyranosyl) -(1-4)-1,2,3,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosylsulfonamide Descriptor: 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranose-(1-4)-(1S)-2,3,6-tri-O-acetyl-1,5-anhydro-1-sulfamoyl-D-glucitol, Carbonic anhydrase 2, GLYCEROL, ... Authors: Paul, B, Poulsen, S.-A, Hofmann, A. Deposit date: 2009-05-25 Release date: 2009-10-13 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases. J.Med.Chem., 52, 2009
3VU4	Crystal structure of Kluyvelomyces marxianus Hsv2 Descriptor: KmHsv2, SULFATE ION Authors: Watanabe, Y, Noda, N.N. Deposit date: 2012-06-15 Release date: 2012-07-04 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-based analyses reveal distinct binding sites for Atg2 and phosphoinositides in Atg18. J.Biol.Chem., 287, 2012
3VZ8	Crystal Structure Analysis of the Mini-chaperonin variant with Leu 185, Val 186, Pro 187, Arg 188 and Ser 190 replaced with all Gly Descriptor: 60 kDa chaperonin Authors: Saijo, S, Sato, T. Deposit date: 2012-10-09 Release date: 2013-11-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Binding Energy(BE) from Crystal Packing of Mini-chaperones (mcpn) Provided Insights into the Allosteric Interaction of GroEL/ES Complex To be Published
3HKQ	Human carbonic anhydrase II in complex with 1-S-D-Galactopyranosylsulfonamide Descriptor: (1S)-1,5-anhydro-1-sulfamoyl-D-galactitol, Carbonic anhydrase 2, GLYCEROL, ... Authors: Paul, B, Poulsen, S.-A, Hofmann, A. Deposit date: 2009-05-25 Release date: 2009-10-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases. J.Med.Chem., 52, 2009
4PLU	Crystal structure of Macrophage Migration Inhibitory Factor in complex with benzaldehyde Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2014-05-19 Release date: 2015-09-30 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.63 Å) Cite: An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4PKZ	Crystal structure of P1M mutant of Macrophage Migration Inhibitory Factor Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION Authors: Pantouris, G, Lolis, E. Deposit date: 2014-05-15 Release date: 2015-09-30 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
1MFF	MACROPHAGE MIGRATION INHIBITORY FACTOR Y95F MUTANT Descriptor: MACROPHAGE MIGRATION INHIBITORY FACTOR Authors: Taylor, A.B, Stamps, S.L, Wang, S.C, Hackert, M.L, Whitman, C.P. Deposit date: 1998-10-19 Release date: 1999-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants. Biochemistry, 39, 2000
3VGO	Crystal structure of the N-terminal fragment of Cbl-b Descriptor: E3 ubiquitin-protein ligase CBL-B Authors: Kobashigawa, Y, Noda, N.N, Inagaki, F. Deposit date: 2011-08-18 Release date: 2011-12-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108, 2011
2LQ8	Domain interaction in Thermotoga maritima NusG Descriptor: Transcription antitermination protein nusG Authors: Droegemueller, J, Stegmann, C, Burmann, B, Roesch, P, Wahl, M.C, Schweimer, K. Deposit date: 2012-02-27 Release date: 2013-01-23 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: An Autoinhibited State in the Structure of Thermotoga maritima NusG. Structure, 21, 2013
6STY	Human REXO2 exonuclease in complex with RNA. Descriptor: CALCIUM ION, Oligoribonuclease, mitochondrial, ... Authors: Malik, D, Szewczyk, M, Szczesny, R, Nowotny, M. Deposit date: 2019-09-12 Release date: 2020-04-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA. Nucleic Acids Res., 48, 2020
2LHJ	NMR structure of the high mobility group protein-like protein NHP1 from Babesia bovis T2Bo (BaboA.00841.a) Descriptor: High mobility group protein homolog NHP1 Authors: Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-08-11 Release date: 2011-08-24 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: 1H and 15N Assigned Chemical Shifts for high mobility group protein-like protein NHP1 from Babesia bovis To be Published
3IL9	Structure of E. coli FabH Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 3 Authors: Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. Deposit date: 2009-08-06 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
6C1I	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid Authors: Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J. Deposit date: 2018-01-04 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.26 Å) Cite: A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma. Nat Commun, 9, 2018
3IN7	Crystal Structure of the Grb2 SH2 Domain in Complex with a Cyclopropyl-constrained Ac-pY-Q-N-NH2 Tripeptide Mimic Descriptor: Growth factor receptor-bound protein 2, N~2~-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-D-glutaminyl-D-aspartamide Authors: Clements, J.H. Deposit date: 2009-08-11 Release date: 2009-11-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization. J.Am.Chem.Soc., 131, 2009
3VX7	Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex Descriptor: E1, E2 Authors: Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. Deposit date: 2012-09-11 Release date: 2012-11-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat.Struct.Mol.Biol., 19, 2012
3IB9	Propionyl-CoA Carboxylase Beta Subunit, D422L Descriptor: BIOTIN, Propionyl-CoA carboxylase complex B subunit, SULFATE ION Authors: Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Pham, H, Melgar, M.M. Deposit date: 2009-07-15 Release date: 2010-06-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
3ID9	Crystal structure of a MutT/NUDIX family protein from Bacillus thuringiensis Descriptor: CHLORIDE ION, MutT/NUDIX family protein, SULFATE ION Authors: Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-07-20 Release date: 2009-09-08 Last modified: 2021-02-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Crystal structure of a MutT/NUDIX family protein from Bacillus thuringiensis To be Published
1MIF	MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) Descriptor: MACROPHAGE MIGRATION INHIBITORY FACTOR Authors: Sun, H.-W, Lolis, E. Deposit date: 1996-01-26 Release date: 1996-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor. Proc.Natl.Acad.Sci.USA, 93, 1996
2YF4	Crystal structure of DR2231, the MazG-like protein from Deinococcus radiodurans, Apo structure Descriptor: GLYCEROL, MAZG-LIKE NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE, SULFATE ION Authors: Goncalves, A.M.D, deSanctis, D, McSweeney, S.M. Deposit date: 2011-04-01 Release date: 2011-07-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
3IA3	A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin Descriptor: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE Authors: Feng, L, Jeffrey, P.D, Shi, Y. Deposit date: 2009-07-13 Release date: 2009-07-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin. J.Biol.Chem., 284, 2009
3UKM	Crystal structure of the human two pore domain potassium ion channel K2P1 (TWIK-1) Descriptor: POTASSIUM ION, Potassium channel subfamily K member 1, UNDECANE Authors: Long, S.B, Miller, A.N. Deposit date: 2011-11-09 Release date: 2012-02-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Crystal structure of the human two-pore domain potassium channel K2P1. Science, 335, 2012

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