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2SXL
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SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: SEX-LETHAL PROTEIN
Authors:Inoue, M, Muto, Y, Sakamoto, H, Kigawa, T, Takio, K, Shimura, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-07-16
Release date:1998-07-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
J.Mol.Biol., 272, 1997
2RU3
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BU of 2ru3 by Molmil
Solution structure of c.elegans SUP-12 RRM in complex with RNA
Descriptor: Protein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3')
Authors:Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y.
Deposit date:2013-11-12
Release date:2014-08-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
6CMN
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BU of 6cmn by Molmil
Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7
Descriptor: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element
Authors:Belashov, I.A, Wedekind, J.E.
Deposit date:2018-03-05
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.
Nucleic Acids Res., 46, 2018
6C8U
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BU of 6c8u by Molmil
Solution structure of Musashi2 RRM1
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
6DG1
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BU of 6dg1 by Molmil
NMR structure of the second qRRM2 domain of human hnRNP H
Descriptor: qRRM2 domain of Heterogeneous nuclear ribonucleoprotein H2
Authors:Srinivasa, R.P.
Deposit date:2018-05-16
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
6E4N
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Structure of the T. brucei TbRGG2 RRM domain: apo R3 crystal form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4O
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BU of 6e4o by Molmil
Structure of apo T. brucei RRM: P4(1)2(1)2 form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4P
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BU of 6e4p by Molmil
Structure of the T. brucei RRM domain in complex with RNA
Descriptor: RNA (5'-R(P*UP*UP*UP*U)-3'), RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6ELD
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BU of 6eld by Molmil
Crystal structure of TIA-1 RRM1 in complex with U1C
Descriptor: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C
Authors:Jagtap, P.K.A, Sattler, M.
Deposit date:2017-09-28
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Crystal structure of TIA-1 RRM1 in complex with U1C
To Be Published
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
6DG0
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BU of 6dg0 by Molmil
MEC-8 C-terminal RRM domain bound to AGCACA
Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
Authors:Mackereth, C.D, Soufari, H.
Deposit date:2018-05-16
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.457 Å)
Cite:Structure of MEC-8 RRM2 in complex with AGCACA
To Be Published
2X1A
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BU of 2x1a by Molmil
Structure of Rna15 RRM with RNA bound (G)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2QFJ
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BU of 2qfj by Molmil
Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE
Descriptor: DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor
Authors:Crichlow, G.V, Yang, Y, Fan, C, Lolis, E, Braddock, D.
Deposit date:2007-06-27
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition
EMBO J., 27, 2007
2X1B
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BU of 2x1b by Molmil
Structure of RNA15 RRM
Descriptor: MRNA 3'-END-PROCESSING PROTEIN RNA15, PHOSPHATE ION
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2RNE
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BU of 2rne by Molmil
Solution structure of the second RNA recognition motif (RRM) of TIA-1
Descriptor: Tia1 protein
Authors:Takahashi, M, Kuwasako, K, Abe, C, Tsuda, K, Inoue, M, Terada, T, Shirouzu, M, Kobayashi, N, Kigawa, T, Taguchi, S, Guntert, P, Hayashizaki, Y, Tanaka, A, Muto, Y, Yokoyama, S.
Deposit date:2007-12-19
Release date:2008-11-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second RNA recognition motif (RRM) domain of murine T cell intracellular antigen-1 (TIA-1) and its RNA recognition mode
Biochemistry, 47, 2008
3UCU
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BU of 3ucu by Molmil
The c-di-GMP-I riboswitch bound to pGpG
Descriptor: MAGNESIUM ION, RNA (92-MER), U1 small nuclear ribonucleoprotein A, ...
Authors:Smith, K.D, Strobel, S.A.
Deposit date:2011-10-27
Release date:2012-01-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer.
Biochemistry, 51, 2012
3S7R
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BU of 3s7r by Molmil
Crystal structure of a Heterogeneous nuclear ribonucleoprotein A/B (HNRPAB) from HOMO SAPIENS at 2.15 A resolution
Descriptor: Heterogeneous nuclear ribonucleoprotein A/B, UNKNOWN LIGAND
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL), Partnership for Stem Cell Biology (STEMCELL)
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a Heterogeneous nuclear ribonucleoprotein A/B (HNRPAB) from Homo sapiens at 2.15 A resolution
To be published
3UWT
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BU of 3uwt by Molmil
Crystal structure of a RNA binding domain of poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 2.50 A resolution
Descriptor: CHLORIDE ION, Poly(U)-binding-splicing factor PUF60
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2011-12-02
Release date:2012-01-11
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a RNA binding domain of poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 2.50 A resolution
To be published
3VAL
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BU of 3val by Molmil
Structure of U2AF65 variant with BrU5C1 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ...
Authors:Jenkins, J.L, Frato, K.H, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAK
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BU of 3vak by Molmil
Structure of U2AF65 variant with BrU5 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3V4M
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BU of 3v4m by Molmil
Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution
Descriptor: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2011-12-15
Release date:2012-06-13
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution
To be published
3SMZ
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BU of 3smz by Molmil
Human raver1 RRM1-3 domains (residues 39-320)
Descriptor: Ribonucleoprotein PTB-binding 1, SULFATE ION
Authors:Rangarajan, E.S, Lee, J.H, Izard, T.
Deposit date:2011-06-28
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Apo raver1 structure reveals distinct RRM domain orientations.
Protein Sci., 20, 2011
3VAF
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BU of 3vaf by Molmil
Structure of U2AF65 variant with BrU3 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAM
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BU of 3vam by Molmil
Structure of U2AF65 variant with BrU5C2 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3SXL
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SEX-LETHAL RNA RECOGNITION DOMAINS 1 AND 2 FROM DROSOPHILA MELANOGASTER
Descriptor: PROTEIN (SEX-LETHAL)
Authors:Crowder, S.M, Kanaar, R, Rio, D.C, Alber, T.C.
Deposit date:1999-04-04
Release date:1999-04-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Absence of interdomain contacts in the crystal structure of the RNA recognition motifs of Sex-lethal.
Proc.Natl.Acad.Sci.USA, 96, 1999

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数据于2024-09-18公开中

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