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8JLD
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BU of 8jld by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8JLB
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BU of 8jlb by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
5XAH
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BU of 5xah by Molmil
Crystal structure of human Importin4
Descriptor: Importin-4
Authors:Song, J.J, Yoon, J.
Deposit date:2017-03-13
Release date:2018-02-14
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
4U7P
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BU of 4u7p by Molmil
Crystal structure of DNMT3A-DNMT3L complex
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y.
Deposit date:2014-07-31
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.821 Å)
Cite:Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
6LKB
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BU of 6lkb by Molmil
Crystal Structure of the peptidylprolyl isomerase domain of Arabidopsis thaliana CYP71.
Descriptor: COBALT (II) ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Lakhanpal, S, Jobichen, C, Swaminathan, K.
Deposit date:2019-12-18
Release date:2020-12-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Structural and functional analyses of the PPIase domain of Arabidopsis thaliana CYP71 reveal its catalytic activity toward histone H3.
Febs Lett., 595, 2021
5KDM
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BU of 5kdm by Molmil
Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Huang, H, Patel, D.
Deposit date:2016-06-08
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis underlying viral hijacking of a histone chaperone complex.
Nat Commun, 7, 2016
6YN1
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BU of 6yn1 by Molmil
Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer
Descriptor: Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ...
Authors:Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K.
Deposit date:2020-04-10
Release date:2021-11-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.
Sci Adv, 8, 2022
2B2Y
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BU of 2b2y by Molmil
Tandem chromodomains of human CHD1
Descriptor: Chromodomain-helicase-DNA-binding protein 1
Authors:Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
5XM1
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BU of 5xm1 by Molmil
The mouse nucleosome structure containing H2A, H2B type3-A, H3mm7, and H4
Descriptor: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
Authors:Taguchi, H, Horikoshi, N, Kurumizaka, H.
Deposit date:2017-05-12
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
7K7G
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BU of 7k7g by Molmil
nucleosome and Gal4 complex
Descriptor: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ...
Authors:Ruifang, G, Yawen, B.
Deposit date:2020-09-22
Release date:2021-03-31
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
7TRL
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BU of 7trl by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, Histone H3, ...
Authors:Klein, B.J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2022-01-29
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
2F6J
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BU of 2f6j by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
Descriptor: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3W98
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BU of 3w98 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region
Descriptor: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2013-04-01
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
2HUE
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BU of 2hue by Molmil
Structure of the H3-H4 chaperone Asf1 bound to histones H3 and H4
Descriptor: Anti-silencing protein 1, GLYCEROL, Histone H3, ...
Authors:English, C.M, Churchill, M.E.A, Tyler, J.K.
Deposit date:2006-07-26
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the histone chaperone activity of asf1.
Cell(Cambridge,Mass.), 127, 2006
7Y5U
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BU of 7y5u by Molmil
Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5V
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BU of 7y5v by Molmil
Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7KEZ
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BU of 7kez by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 16_0325) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Manenda, M.S, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF1
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BU of 7kf1 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 14_0130) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Picard, M.-E, Manenda, M.S.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF0
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BU of 7kf0 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, ...
Authors:Shi, R, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7VCQ
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BU of 7vcq by Molmil
structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
2LH0
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BU of 2lh0 by Molmil
NMR structure of the histone-interacting N-terminal homodimeric region of Rtt106
Descriptor: Histone chaperone RTT106
Authors:Hu, Q, Cui, G, Mer, G.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
1XNI
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BU of 1xni by Molmil
Tandem Tudor Domain of 53BP1
Descriptor: Tumor suppressor p53-binding protein 1
Authors:Huyen, Y, Zgheib, O, DiTullio Jr, R.A, Gorgoulis, V.G, Zacharatos, P, Petty, T.J, Sheston, E.A, Mellert, H.S, Stavridi, E.S, Halazonetis, T.D.
Deposit date:2004-10-05
Release date:2004-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
Nature, 432, 2004
3A1B
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BU of 3a1b by Molmil
Crystal structure of the DNMT3A ADD domain in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ...
Authors:Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M.
Deposit date:2009-03-28
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10, 2009
5T1I
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BU of 5t1i by Molmil
CBX3 chromo shadow domain in complex with histone H3 peptide
Descriptor: Chromobox protein homolog 3, Histone H3.1, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-08-19
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.
J. Biol. Chem., 292, 2017
4A7J
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BU of 4a7j by Molmil
Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance
Descriptor: HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5
Authors:Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E.
Deposit date:2011-11-14
Release date:2012-01-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance
Nat.Struct.Mol.Biol., 19, 2012

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数据于2024-06-12公开中

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