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6QTZ
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BU of 6qtz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-02-26
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
8XKL
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BU of 8xkl by Molmil
Structure of ACPII-CCPII from cryptophyte algae
Descriptor: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ...
Authors:Li, X.Y, Mao, Z.Y, Shen, J.R, Han, G.Y.
Deposit date:2023-12-23
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structure and distinct supramolecular organization of a PSII-ACPII dimer from a cryptophyte alga Chroomonas placoidea.
Nat Commun, 15, 2024
6QM7
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BU of 6qm7 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Z6K
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BU of 6z6k by Molmil
Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6CFL
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BU of 6cfl by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S.
Deposit date:2018-02-15
Release date:2018-03-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.
J. Mol. Biol., 430, 2018
6ZJ3
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BU of 6zj3 by Molmil
Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis
Descriptor: 18S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Matzov, D, Halfon, H, Zimmerman, E, Rozenberg, H, Bashan, A, Gray, M.W, Yonath, A.E, Shalev-Benami, M.
Deposit date:2020-06-27
Release date:2020-10-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis.
Nucleic Acids Res., 48, 2020
6QW6
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BU of 6qw6 by Molmil
Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Charenton, C, Wilkinson, M.E, Nagai, K.
Deposit date:2019-03-05
Release date:2019-04-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
8VHB
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BU of 8vhb by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Alpha-Ketoglutarate
Descriptor: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, 2-OXOGLUTARIC ACID, CALCIUM ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
6QZF
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BU of 6qzf by Molmil
The cryo-EM structure of the collar complex and tail axis in genome emptied bacteriophage phi29
Descriptor: Portal protein, Pre-neck appendage protein, Proximal tail tube connector protein
Authors:Xu, J, Wang, D, Gui, M, Xiang, Y.
Deposit date:2019-03-11
Release date:2019-06-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural assembly of the tailed bacteriophage φ29.
Nat Commun, 10, 2019
8V83
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BU of 8v83 by Molmil
60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
5L3S
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BU of 5l3s by Molmil
Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY
Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Bange, G, Wild, K, Sinning, I.
Deposit date:2016-05-24
Release date:2016-06-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
8V84
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BU of 8v84 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
6ZI5
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BU of 6zi5 by Molmil
Ultrafast Structural Response to Charge Redistribution Within a Photosynthetic Reaction Centre - 300 ps (a) structure
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Baath, P, Dods, R, Braenden, G, Neutze, R.
Deposit date:2020-06-24
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ultrafast structural changes within a photosynthetic reaction centre.
Nature, 589, 2021
6QNQ
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BU of 6qnq by Molmil
70S ribosome initiation complex (IC) with experimentally assigned potassium ions
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2019-02-11
Release date:2019-06-19
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019
5L55
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BU of 5l55 by Molmil
Yeast 20S proteasome in complex with epoxyketone inhibitor 18
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-27
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016
6GXP
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BU of 6gxp by Molmil
Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP(RF3-only)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
5L5R
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BU of 5l5r by Molmil
Yeast 20S proteasome with human beta5i (1-138;V31M) and human beta6 (97-111; 118-133)
Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016
5L67
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BU of 5l67 by Molmil
Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with PR-924
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016
8V87
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BU of 8v87 by Molmil
60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8VS9
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BU of 8vs9 by Molmil
Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site and deacyl-tRNA in the E site of E. coli 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Teran, D, Zhang, Y, Korostelev, A.A.
Deposit date:2024-01-23
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon.
Front Microbiol, 15, 2024
8VSA
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BU of 8vsa by Molmil
Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site of E. coli 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Teran, D, Zhang, Y, Korostelev, A.A.
Deposit date:2024-01-23
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon.
Front Microbiol, 15, 2024
2JN4
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BU of 2jn4 by Molmil
Solution NMR Structure of Protein RP4601 from Rhodopseudomonas palustris. Northeast Structural Genomics Consortium Target RpT2; Ontario Center for Structural Proteomics Target RP4601.
Descriptor: Hypothetical protein fixU, nifT
Authors:Lemak, A, Srisailam, S, Yee, A, Karra, M.D, Lukin, J.A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-12-22
Release date:2007-01-23
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution structure of a hypothetical protein RP4601 from Rhodopseudomonas palustris
To be Published
5L8R
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BU of 5l8r by Molmil
The structure of plant photosystem I super-complex at 2.6 angstrom resolution.
Descriptor: (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Mazor, Y, Borovikova, A, Caspy, I, Nelson, N.
Deposit date:2016-06-08
Release date:2017-03-15
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the plant photosystem I supercomplex at 2.6 angstrom resolution.
Nat Plants, 3, 2017
5L52
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BU of 5l52 by Molmil
Yeast 20S proteasome in complex with epoxyketone inhibitor 14
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-27
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016
5L5S
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BU of 5l5s by Molmil
Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with PR-924
Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016

224201

数据于2024-08-28公开中

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