PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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9B84	Cryo-EM structure of human ADAR1 in complex with dsRNA derived from HT2C gene Descriptor: INOSITOL HEXAKISPHOSPHATE, Maltodextrin-binding protein,Double-stranded RNA-specific adenosine deaminase, RNA (66-MER), ... Authors: Deng, X, Gao, Y. Deposit date: 2024-03-28 Release date: 2025-03-26 Last modified: 2025-04-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Biochemical profiling and structural basis of ADAR1-mediated RNA editing. Mol.Cell, 85, 2025
9B89	Cryo-EM structure of human ADAR1 in complex with dsRNA derived from HT2C gene in the pre-editing state Descriptor: INOSITOL HEXAKISPHOSPHATE, Maltodextrin-binding protein,Double-stranded RNA-specific adenosine deaminase, RNA (71-MER), ... Authors: Deng, X, Gao, Y. Deposit date: 2024-03-29 Release date: 2025-03-26 Last modified: 2025-04-16 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: Biochemical profiling and structural basis of ADAR1-mediated RNA editing. Mol.Cell, 85, 2025
6H57	Crystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesis Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... Authors: Roychowdhury, A, Graille, M. Deposit date: 2018-07-24 Release date: 2019-06-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis. Nucleic Acids Res., 47, 2019
1BYX	CHIMERIC HYBRID DUPLEX R(GCAGUGGC).R(GCCA)D(CTGC) COMPRISING THE TRNA-DNA JUNCTION FORMED DURING INITIATION OF HIV-1 REVERSE TRANSCRIPTION Descriptor: DNA/RNA (5'-R(*GP*CP*CP*A)-D(P*CP*TP*GP*C)-3'), RNA (5'-R(*GP*CP*AP*GP*UP*GP*GP*C)-3') Authors: Szyperski, T, Goette, M, Billeter, M, Perola, E, Cellai, L. Deposit date: 1998-10-20 Release date: 1999-10-20 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription. J.Biomol.NMR, 13, 1999
5MPS	Structure of a spliceosome remodeled for exon ligation Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... Authors: Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. Deposit date: 2016-12-18 Release date: 2017-01-18 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.85 Å) Cite: Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
5JS1	Human Argonaute2 Bound to an siRNA Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ... Authors: Schirle, N.T, MacRae, I.J. Deposit date: 2016-05-07 Release date: 2016-07-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.499 Å) Cite: Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138, 2016
7XW2	Cryo-EM structure of human DICER-pre-miRNA in a dicing state Descriptor: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER) Authors: Lee, H, Roh, S.-H. Deposit date: 2022-05-26 Release date: 2023-03-08 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Structure of the human DICER-pre-miRNA complex in a dicing state. Nature, 615, 2023
7DU2	RNA polymerase III EC complex in post-translocation state Descriptor: DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... Authors: Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. Deposit date: 2021-01-07 Release date: 2021-03-17 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
1IBM	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. Deposit date: 2001-03-28 Release date: 2001-05-04 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 2001
1IBL	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE AND WITH THE ANTIBIOTIC PAROMOMYCIN Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. Deposit date: 2001-03-28 Release date: 2001-05-04 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 2001
8KDA	Cryo-EM structure of Hydrogenobacter thermophilus minimal protein-only RNase P (HARP) in complex with pre-tRNAs Descriptor: Aquifex aeolicus pre-tRNAVal, MAGNESIUM ION, RNA-free ribonuclease P Authors: Teramoto, T, Adachi, N, Yokogawa, T, Koyasu, T, Mayanagi, K, Nakamura, T, Senda, T, Kakuta, Y. Deposit date: 2023-08-09 Release date: 2024-08-14 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: Structural basis of transfer RNA processing by bacterial minimal RNase P Nat Commun, 16, 2025
4M7D	Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU Descriptor: U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... Authors: Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. Deposit date: 2013-08-12 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.595 Å) Cite: Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
4M7A	Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA Descriptor: U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... Authors: Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. Deposit date: 2013-08-12 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.781 Å) Cite: Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
8KD9	Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs Descriptor: Aquifex aeolicus pre-tRNAVal, RNA-free ribonuclease P Authors: Teramoto, T, Koyasu, T, Mayanagi, K, Yokogawa, T, Adachi, N, Nakamura, T, Senda, T, Kakuta, Y. Deposit date: 2023-08-09 Release date: 2024-08-14 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (2.87 Å) Cite: Structural basis of transfer RNA processing by bacterial minimal RNase P Nat Commun, 16, 2025
3J7A	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... Authors: Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. Deposit date: 2014-06-03 Release date: 2014-07-16 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
3Q1R	Crystal structure of a bacterial RNase P holoenzyme in complex with TRNA and in the presence of 5' leader Descriptor: MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component, ... Authors: Reiter, N.J, Ostermanm, A, Torres-Larios, A, Swinger, K.K, Pan, T, Mondragon, A. Deposit date: 2010-12-17 Release date: 2011-03-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4.21 Å) Cite: Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA. Nature, 468, 2010
7Y18	Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Saccharomyces cerevisiae Descriptor: Polynucleotide 5'-hydroxyl-kinase GRC3, Protein LAS1 Authors: Chen, J, Liu, L. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.69 Å) Cite: Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
8V1I	Crystal structure of human mascRNA Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... Authors: Skeparnias, I, Zhang, J. Deposit date: 2023-11-20 Release date: 2024-07-10 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of MALAT1 RNA maturation and mascRNA biogenesis. Nat.Struct.Mol.Biol., 31, 2024
3Q1Q	Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA Descriptor: MAGNESIUM ION, PHOSPHATE ION, RNase P RNA, ... Authors: Reiter, N.J, Osterman, A, Torres-Larios, A, Swinger, K.K, Pan, T, Mondragon, A. Deposit date: 2010-12-17 Release date: 2011-03-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA. Nature, 468, 2010
7Y17	Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Cyberlindnera jadinii Descriptor: LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3 Authors: Chen, J, Liu, L. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.39 Å) Cite: Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
6QNW	Influenza A Polymerase Heterotrimer Human H3N2 Northern Territory 1968 Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit Authors: Keown, J.R, Fan, H, Grimes, J.M. Deposit date: 2019-02-12 Release date: 2019-09-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6QPF	Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit Authors: Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. Deposit date: 2019-02-13 Release date: 2019-09-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.634 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
8UX8	E. coli 70S ribosome with unmodified Lys-tRNAPro(GGG) bound to slippery P-site CCC-C codon in the +1 mRNA reading frame Descriptor: 16S ribosomal RNA, 23S rRNA, 30S ribosomal protein S11, ... Authors: Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. Deposit date: 2023-11-09 Release date: 2025-07-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting Nat Commun, 2025
8V03	E. coli 70S ribosome with unmodified P/E-tRNAPro(GGG) bound to slippery P-site CCC-C codon Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S11, ... Authors: Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. Deposit date: 2023-11-16 Release date: 2025-07-09 Method: ELECTRON MICROSCOPY (4 Å) Cite: An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting Nat Commun, 2025
4BBR	Structure of RNA polymerase II-TFIIB complex Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Sainsbury, S, Niesser, J, Cramer, P. Deposit date: 2012-09-27 Release date: 2012-11-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex Nature, 493, 2013

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