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5L61
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BU of 5l61 by Molmil
Yeast 20S proteasome with human beta5c (1-138) and human beta6 (99-132) in complex with epoxyketone inhibitor 14
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2016-05-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
EMBO J., 35, 2016
6FVY
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BU of 6fvy by Molmil
26S proteasome, s6 state
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
Authors:Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E.
Deposit date:2018-03-05
Release date:2018-08-22
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
Deposit date:2024-02-02
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
2JD7
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BU of 2jd7 by Molmil
Crystal Structure of the Fe-soaked Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus furiosus
Descriptor: FE (III) ION, FERRITIN HOMOLOG, SULFATE ION
Authors:Tatur, J, Hagen, W.R, Matias, P.M.
Deposit date:2007-01-05
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus Furiosus
J.Biol.Inorg.Chem., 12, 2007
6ZGI
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BU of 6zgi by Molmil
Furin Cleaved Spike Protein of SARS-CoV-2 in Closed Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrobel, A.G, Benton, D.J, Rosenthal, P.B, Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
8WUW
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BU of 8wuw by Molmil
Cryo-EM structure of H. thermophilus GroEL-GroES2 asymmetric football complex
Descriptor: Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ...
Authors:Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S.
Deposit date:2023-10-21
Release date:2024-03-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into thermophilic chaperonin complexes.
Structure, 32, 2024
6QGB
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BU of 6qgb by Molmil
Crystal structure of Ideonella sakaiensis MHETase bound to benzoic acid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BENZOIC ACID, CALCIUM ION, ...
Authors:Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G.
Deposit date:2019-01-10
Release date:2019-04-03
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate.
Nat Commun, 10, 2019
6ZI9
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BU of 6zi9 by Molmil
Ultrafast Structural Response to Charge Redistribution Within a Photosynthetic Reaction Centre - 300 ps (b) structure
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Baath, P, Dods, R, Braenden, G, Neutze, R.
Deposit date:2020-06-25
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ultrafast structural changes within a photosynthetic reaction centre.
Nature, 589, 2021
2JJ2
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BU of 2jj2 by Molmil
The Structure of F1-ATPase inhibited by quercetin.
Descriptor: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE GAMMA CHAIN, ...
Authors:Gledhill, J.R, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2007-07-03
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of Inhibition of Bovine F1-ATPase by Resveratrol and Related Polyphenols.
Proc.Natl.Acad.Sci.USA, 104, 2007
8XON
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BU of 8xon by Molmil
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Xu, X, Long, F.
Deposit date:2024-01-01
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Structural insights into the Clp protein degradation machinery.
Mbio, 15, 2024
6QH0
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BU of 6qh0 by Molmil
The complex structure of hsRosR-S5 (VNG0258H/RosR-S5)
Descriptor: DNA (28-MER), MANGANESE (II) ION, SULFATE ION, ...
Authors:Shaanan, B, Kutnowski, N.
Deposit date:2019-01-14
Release date:2019-07-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR.
Nucleic Acids Res., 47, 2019
6C4J
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BU of 6c4j by Molmil
Ligand bound full length hUGDH with A104L substitution
Descriptor: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-1,2-PROPANEDIOL, ...
Authors:Beattie, N.R, Pioso, B.J, Wood, Z.A, Sidlo, A.M.
Deposit date:2018-01-12
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core.
Biochemistry, 57, 2018
6Z7R
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BU of 6z7r by Molmil
Structure of [NiFeSe] hydrogenase from Desulfovibrio vulgaris hildenborough pressurized with Krypton gas - structure wtKr1
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE (II) ION, ...
Authors:Zacarias, S, Temporao, A, Carpentier, P, van der Linden, P, Pereira, I.A.C, Matias, P.M.
Deposit date:2020-06-01
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Exploring the gas access routes in a [NiFeSe] hydrogenase using crystals pressurized with krypton and oxygen.
J.Biol.Inorg.Chem., 25, 2020
6QIL
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BU of 6qil by Molmil
The complex structure of hsRosR-S1 (VNG0258H/RosR-S1)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (28-MER), DNA binding protein, ...
Authors:Shaanan, B, Kutnowski, N.
Deposit date:2019-01-21
Release date:2019-07-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR.
Nucleic Acids Res., 47, 2019
6BZ5
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BU of 6bz5 by Molmil
Structure and mechanism of salicylate hydroxylase from Pseudomonas putida G7
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ...
Authors:Nagem, R.A.P, Costa, D.M.A.
Deposit date:2017-12-22
Release date:2018-12-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Catalytic mechanism for the conversion of salicylate into catechol by the flavin-dependent monooxygenase salicylate hydroxylase.
Int.J.Biol.Macromol., 129, 2019
2JKN
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BU of 2jkn by Molmil
DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form)
Descriptor: 1,2-ETHANEDIOL, CHLORAMPHENICOL SUCCINATE, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, ...
Authors:Pettigrew, D.M, Roversi, P, Davies, S.G, Russell, A.J, Lea, S.M.
Deposit date:2008-08-28
Release date:2008-12-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Acta Crystallogr. D Biol. Crystallogr., 65, 2009
6ZKF
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BU of 6zkf by Molmil
Complex I during turnover, open3
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Kampjut, D, Sazanov, L.A.
Deposit date:2020-06-30
Release date:2020-10-14
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
2JKV
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BU of 2jkv by Molmil
Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, CHLORIDE ION, ...
Authors:Pilka, E.S, Kavanagh, K.L, von Delft, F, Muniz, J.R.C, Murray, J, Picaud, S, Guo, K, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Oppermann, U.
Deposit date:2008-09-01
Release date:2009-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Structure of Human Phosphogluconate Dehydrogenase in Complex with Nadph at 2.53A
To be Published
6ZKU
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BU of 6zku by Molmil
Deactive complex I, open3
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE MONOPHOSPHATE, ...
Authors:Kampjut, D, Sazanov, L.A.
Deposit date:2020-06-30
Release date:2020-10-07
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6QKK
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BU of 6qkk by Molmil
Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogue (1)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]benzamide, ...
Authors:Davis, S, Bueno, R.V, Dawson, A, Hunter, W.N.
Deposit date:2019-01-29
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions between 2'-fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine-binding protein inform on potent antagonist activity against nicotinic receptors
Acta Crystallogr.,Sect.D, 78, 2022
2JKR
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BU of 2jkr by Molmil
AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
6CAO
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BU of 6cao by Molmil
Structure of the ribosomal decoding complex at ambient temperature
Descriptor: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure of the 30S ribosomal decoding complex at ambient temperature.
RNA, 24, 2018
8WUX
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BU of 8wux by Molmil
Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex
Descriptor: Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ...
Authors:Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S.
Deposit date:2023-10-21
Release date:2024-03-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into thermophilic chaperonin complexes.
Structure, 32, 2024
6BY7
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BU of 6by7 by Molmil
Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins
Descriptor: DNA (26-MER), DNA (27-MER), DNA (29-MER), ...
Authors:Dong, Y, Chen, S, Zhang, S, Sodroski, J, Yang, Z, Liu, D, Mao, Y.
Deposit date:2017-12-20
Release date:2018-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins.
Angew. Chem. Int. Ed. Engl., 57, 2018
6C0Y
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BU of 6c0y by Molmil
Lysinoalanine synthase, DurN, from duramycin biosynthesis bound to duramycin
Descriptor: CYS-LYS-GLN-DAL-CYS-ALA-PHE-GLY-PRO-PHE-DBB-PHE-VAL-CYS-BH2-GLY-ASN-DBB-LYS, Lysinoalanine synthase, POTASSIUM ION
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-01-03
Release date:2018-09-05
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Nat. Chem. Biol., 14, 2018

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数据于2024-08-28公开中

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