2HWV
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![BU of 2hwv by Molmil](/molmil-images/mine/2hwv) | Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily. | Descriptor: | DNA-binding response regulator VicR, SULFATE ION | Authors: | Trinh, C.H, Liu, Y, Phillips, S.E.V, Phillips-Jones, M.K. | Deposit date: | 2006-08-02 | Release date: | 2007-01-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the response regulator VicR DNA-binding domain. Acta Crystallogr.,Sect.D, 63, 2007
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2MUG
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![BU of 2mug by Molmil](/molmil-images/mine/2mug) | Protective cellular immunity against P. falciparum malaria merozoite is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex | Descriptor: | Serine-repeat antigen protein | Authors: | Patarroyo, M, Salazar, L, Cifuentes, G, Lozano, J, Delgado, G, Rivera, Z, Rosas, J, Vargas, L. | Deposit date: | 2014-09-09 | Release date: | 2014-10-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Protective cellular immunity against P. falciparum malaria merozoites is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex. Biochimie, 88, 2006
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3CBE
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2HYP
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![BU of 2hyp by Molmil](/molmil-images/mine/2hyp) | Crystal structure of Rv0805 D66A mutant | Descriptor: | BROMIDE ION, CACODYLATE ION, FE (III) ION, ... | Authors: | Shenoy, A.R, Capuder, M, Draskovic, P, Lamba, D, Visweswariah, S.S, Podobnik, M. | Deposit date: | 2006-08-07 | Release date: | 2006-12-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis. J.Mol.Biol., 365, 2007
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2QPS
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![BU of 2qps by Molmil](/molmil-images/mine/2qps) | "Sugar tongs" mutant Y380A in complex with acarbose | Descriptor: | Alpha-amylase type A isozyme, CALCIUM ION | Authors: | Aghajari, N, Jensen, M.H, Tranier, S, Haser, R. | Deposit date: | 2007-07-25 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity Febs J., 274, 2007
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2QQU
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![BU of 2qqu by Molmil](/molmil-images/mine/2qqu) | Crystal structure of a cell-wall invertase (D239A) from Arabidopsis thaliana in complex with sucrose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, ... | Authors: | Lammens, W, Le Roy, K, Van Laere, A, Rabijns, A, Van den Ende, W. | Deposit date: | 2007-07-27 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose. J.Mol.Biol., 377, 2008
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2I32
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2QNO
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![BU of 2qno by Molmil](/molmil-images/mine/2qno) | Crystal Structure of the Mutant E55Q of the Cellulase CEL48F in Complex with a Thio-Oligosaccharide | Descriptor: | 4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose, CALCIUM ION, Endoglucanase F | Authors: | Parsiegla, G, Haser, R. | Deposit date: | 2007-07-19 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of mutants of cellulase Cel48F of Clostridium cellulolyticum in complex with long hemithiocellooligosaccharides give rise to a new view of the substrate pathway during processive action J.Mol.Biol., 375, 2008
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2QQW
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![BU of 2qqw by Molmil](/molmil-images/mine/2qqw) | Crystal structure of a cell-wall invertase (D23A) from Arabidopsis thaliana in complex with sucrose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, ... | Authors: | Lammens, W, Le Roy, K, Van Laere, A, Rabijns, A, Van den Ende, W. | Deposit date: | 2007-07-27 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose. J.Mol.Biol., 377, 2008
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2QFZ
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![BU of 2qfz by Molmil](/molmil-images/mine/2qfz) | Crystal structure of human TBC1 domain family member 22A | Descriptor: | TBC1 domain family member 22A, UNKNOWN ATOM OR ION | Authors: | Tong, Y, Tempel, W, Dimov, S, Dong, A, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-28 | Release date: | 2007-07-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human TBC1 domain family member 22A. To be Published
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2HUR
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![BU of 2hur by Molmil](/molmil-images/mine/2hur) | Escherichia coli nucleoside diphosphate kinase | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | Authors: | Moynie, L, Giraud, M.-F, Georgescauld, F, Lascu, I, Dautant, A. | Deposit date: | 2006-07-27 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family Proteins, 67, 2007
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2QLW
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2HV5
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![BU of 2hv5 by Molmil](/molmil-images/mine/2hv5) | Human Aldose Reductase complexed with inhibitor zopolrestat after three days soaking (3days_soaked_3) | Descriptor: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Steuber, H, Heine, A, Klebe, G. | Deposit date: | 2006-07-27 | Release date: | 2006-10-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J.Mol.Biol., 363, 2006
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2QMK
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![BU of 2qmk by Molmil](/molmil-images/mine/2qmk) | Human pancreatic alpha-amylase complexed with nitrite | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRITE ION, ... | Authors: | Williams, L.K, Maurus, R, Brayer, G.D. | Deposit date: | 2007-07-16 | Release date: | 2008-03-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity Biochemistry, 47, 2008
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2QS8
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![BU of 2qs8 by Molmil](/molmil-images/mine/2qs8) | Crystal structure of a Xaa-Pro dipeptidase with bound methionine in the active site | Descriptor: | MAGNESIUM ION, METHIONINE, Xaa-Pro Dipeptidase | Authors: | Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-07-30 | Release date: | 2007-08-21 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes. Biochemistry, 48, 2009
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2G0F
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2G60
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![BU of 2g60 by Molmil](/molmil-images/mine/2g60) | Structure of anti-FLAG M2 Fab domain | Descriptor: | anti-FLAG M2 Fab heavy chain, anti-FLAG M2 Fab light chain | Authors: | Roosild, T.P. | Deposit date: | 2006-02-23 | Release date: | 2006-09-12 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins. Acta Crystallogr.,Sect.F, 62, 2006
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2QY6
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![BU of 2qy6 by Molmil](/molmil-images/mine/2qy6) | Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7 | Descriptor: | UPF0209 protein yfcK | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Eberle, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-08-13 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the N-terminal domain of UPF0209 protein yfcK from Escherichia coli O157:H7. To be Published
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2R0X
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2R1L
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![BU of 2r1l by Molmil](/molmil-images/mine/2r1l) | OpdA from Agrobacterium radiobacter with bound diethyl thiophosphate from crystal soaking with the compound- 1.95 A | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... | Authors: | Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. | Deposit date: | 2007-08-23 | Release date: | 2008-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
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2R3U
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![BU of 2r3u by Molmil](/molmil-images/mine/2r3u) | Crystal structure of the PDZ deletion mutant of DegS | Descriptor: | Protease degS | Authors: | Clausen, T, Kurzbauer, R. | Deposit date: | 2007-08-30 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev., 21, 2007
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2R4F
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![BU of 2r4f by Molmil](/molmil-images/mine/2r4f) | Substituted Pyrazoles as Hepatselective HMG-COA reductase inhibitors | Descriptor: | (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | Authors: | Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C. | Deposit date: | 2007-08-31 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia. J.Med.Chem., 51, 2008
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2QHF
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![BU of 2qhf by Molmil](/molmil-images/mine/2qhf) | Mycobacterium tuberculosis Chorismate synthase in complex with NCA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Bruning, M, Bourenkov, G.P, Strizhov, N.I, Bartunik, H.D. | Deposit date: | 2007-07-02 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Mycobacterium tuberculosis Chorismate synthase in complex with NCA To be Published
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2QKW
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![BU of 2qkw by Molmil](/molmil-images/mine/2qkw) | Structural basis for activation of plant immunity by bacterial effector protein AvrPto | Descriptor: | Avirulence protein, Protein kinase | Authors: | Xing, W.M, Zou, Y, Liu, Q, Hao, Q, Zhou, J.M, Chai, J.J. | Deposit date: | 2007-07-11 | Release date: | 2007-08-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structural basis for activation of plant immunity by bacterial effector protein AvrPto Nature, 449, 2007
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2G9I
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![BU of 2g9i by Molmil](/molmil-images/mine/2g9i) | Crystal structure of homolog of F420-0:gamma-Glutamyl Ligase from Archaeoglobus fulgidus Reveals a Novel Fold. | Descriptor: | F420-0:gamma-glutamyl ligase | Authors: | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-03-06 | Release date: | 2006-04-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases. J.Mol.Biol., 372, 2007
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