2QMK
Human pancreatic alpha-amylase complexed with nitrite
Summary for 2QMK
| Entry DOI | 10.2210/pdb2qmk/pdb |
| Related | 1BSI 1CPU 1HNY |
| Descriptor | Pancreatic alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | amylase, pichia pastoris, diabetes, catalysis, pancreatic, enzyme, human, hydrolase, anion activation, nitrite, chloride, carbohydrate metabolism, glycoprotein, glycosidase, metal-binding, pyrrolidone carboxylic acid, secreted |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 56238.60 |
| Authors | Williams, L.K.,Maurus, R.,Brayer, G.D. (deposition date: 2007-07-16, release date: 2008-03-25, Last modification date: 2023-08-30) |
| Primary citation | Maurus, R.,Begum, A.,Williams, L.K.,Fredriksen, J.R.,Zhang, R.,Withers, S.G.,Brayer, G.D. Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity Biochemistry, 47:3332-3344, 2008 Cited by PubMed: 18284212DOI: 10.1021/bi701652t PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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