6UA4
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![BU of 6ua4 by Molmil](/molmil-images/mine/6ua4) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (3/4 compressed, 1/4 extended) segment reconstruction. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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6U8R
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![BU of 6u8r by Molmil](/molmil-images/mine/6u8r) | Human IMPDH2 treated with ATP, IMP, and NAD+. Bent (1/4 compressed, 3/4 extended) segment reconstruction. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-05 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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6U9O
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![BU of 6u9o by Molmil](/molmil-images/mine/6u9o) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Fully compressed filament segment reconstruction. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-09 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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6UA5
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![BU of 6ua5 by Molmil](/molmil-images/mine/6ua5) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free interfacial octamer reconstruction. | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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6U8S
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![BU of 6u8s by Molmil](/molmil-images/mine/6u8s) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Filament assembly interface reconstruction. | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-05 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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4DQW
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![BU of 4dqw by Molmil](/molmil-images/mine/4dqw) | Crystal Structure Analysis of PA3770 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Inosine-5'-monophosphate dehydrogenase, ... | Authors: | Labesse, G, Munier-Lehmann, H. | Deposit date: | 2012-02-16 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | MgATP Regulates Allostery and Fiber Formation in IMPDHs. Structure, 21, 2013
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6UAJ
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![BU of 6uaj by Molmil](/molmil-images/mine/6uaj) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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6UC2
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![BU of 6uc2 by Molmil](/molmil-images/mine/6uc2) | |
6UA2
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![BU of 6ua2 by Molmil](/molmil-images/mine/6ua2) | Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | Authors: | Johnson, M.C, Kollman, J.M. | Deposit date: | 2019-09-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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4FEZ
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![BU of 4fez by Molmil](/molmil-images/mine/4fez) | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | Authors: | Osipiuk, J, Maltseva, N, Makowska-Grzyska, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant. To be Published
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4FXS
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![BU of 4fxs by Molmil](/molmil-images/mine/4fxs) | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, MYCOPHENOLIC ACID, ... | Authors: | Osipiuk, J, Maltseva, N, Makowska-Grzyska, M, Jedrzejczak, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-07-03 | Release date: | 2012-07-25 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid. To be Published
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8PW3
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![BU of 8pw3 by Molmil](/molmil-images/mine/8pw3) | |
8Q65
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![BU of 8q65 by Molmil](/molmil-images/mine/8q65) | |
8QQR
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![BU of 8qqr by Molmil](/molmil-images/mine/8qqr) | Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, super-compressed | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5',3'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... | Authors: | Bulvas, O, Kouba, T, Pichova, I. | Deposit date: | 2023-10-06 | Release date: | 2024-08-14 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
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8QQQ
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![BU of 8qqq by Molmil](/molmil-images/mine/8qqq) | Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, compressed | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... | Authors: | Bulvas, O, Kouba, T, Pichova, I. | Deposit date: | 2023-10-06 | Release date: | 2024-08-14 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
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8QQX
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![BU of 8qqx by Molmil](/molmil-images/mine/8qqx) | |
8QQP
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![BU of 8qqp by Molmil](/molmil-images/mine/8qqp) | Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, super-compressed | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... | Authors: | Bulvas, O, Kouba, T, Pichova, I. | Deposit date: | 2023-10-06 | Release date: | 2024-08-14 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
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8S5I
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![BU of 8s5i by Molmil](/molmil-images/mine/8s5i) | |
8S5H
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![BU of 8s5h by Molmil](/molmil-images/mine/8s5h) | |
8S5J
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![BU of 8s5j by Molmil](/molmil-images/mine/8s5j) | |
8S5K
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![BU of 8s5k by Molmil](/molmil-images/mine/8s5k) | |
8S5L
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![BU of 8s5l by Molmil](/molmil-images/mine/8s5l) | |
8S5M
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![BU of 8s5m by Molmil](/molmil-images/mine/8s5m) | |
8QQV
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![BU of 8qqv by Molmil](/molmil-images/mine/8qqv) | |
8QQW
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![BU of 8qqw by Molmil](/molmil-images/mine/8qqw) | |