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3VD6
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BU of 3vd6 by Molmil
Both Zn Fingers of GATA1 Bound to Palindromic DNA Recognition Site, P21 Crystal Form
Descriptor: ACETATE ION, DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), ...
Authors:Jacques, D.A, Ripin, N, Wilkinson-White, L.E, Guss, J.M, Matthews, J.M.
Deposit date:2012-01-04
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA.
Protein Sci., 24, 2015
6AHW
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BU of 6ahw by Molmil
Crystal structure of circular-permutated YibK methyltransferase from Haemophilus influenzae
Descriptor: circular-permutated tRNA (cytidine(34)-2'-O)-methyltransferase
Authors:Chuang, Y.C, Lyu, P.C, Hsu, S.T.D.
Deposit date:2018-08-20
Release date:2019-01-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Untying a Protein Knot by Circular Permutation.
J. Mol. Biol., 431, 2019
2NT4
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BU of 2nt4 by Molmil
Receiver domain from Myxococcus xanthus social motility protein FrzS (H92F mutant)
Descriptor: CHLORIDE ION, Response regulator homolog
Authors:Echols, N, Fraser, J, Weisfield, S, Merlie, J, Zusman, D, Alber, T.
Deposit date:2006-11-06
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Mol.Microbiol., 65, 2007
2NT3
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BU of 2nt3 by Molmil
Receiver domain from Myxococcus xanthus social motility protein FrzS (Y102A Mutant)
Descriptor: Response regulator homolog
Authors:Fraser, J.S, Echols, N, Merlie, J.P, Zusman, D.R, Alber, T.
Deposit date:2006-11-06
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Mol.Microbiol., 65, 2007
3BE7
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BU of 3be7 by Molmil
Crystal structure of Zn-dependent arginine carboxypeptidase
Descriptor: ARGININE, GLYCEROL, MAGNESIUM ION, ...
Authors:Patskovsky, Y, Ramagopal, U.A, Toro, R, Meyer, A.J, Freeman, J, Iizuka, M, Bain, K, Rodgers, L, Raushel, F, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-11-16
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes.
Biochemistry, 48, 2009
2XO4
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BU of 2xo4 by Molmil
RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
Deposit date:2010-08-09
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
8WZI
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BU of 8wzi by Molmil
One RBD up state of Spike glycoprotein, SARS-CoV-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yadav, S, Vinothkumar, K.R.
Deposit date:2023-11-01
Release date:2024-07-10
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024
1GRT
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BU of 1grt by Molmil
HUMAN GLUTATHIONE REDUCTASE A34E/R37W MUTANT
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F.
Deposit date:1996-12-17
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
3KZ1
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BU of 3kz1 by Molmil
Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ...
Authors:Chen, Z, Sternweis, P.C, Sprang, S.R.
Deposit date:2009-12-07
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
3DXS
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BU of 3dxs by Molmil
Crystal structure of a copper binding domain from HMA7, a P-type ATPase
Descriptor: Copper-transporting ATPase RAN1, LITHIUM ION, ZINC ION
Authors:Zimmermann, M, Xiao, Z, Clarke, O.B, Gulbis, J.M, Wedd, A.G.
Deposit date:2008-07-25
Release date:2009-08-11
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains.
Biochemistry, 48, 2009
2FJU
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BU of 2fju by Molmil
Activated Rac1 bound to its effector phospholipase C beta 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ...
Authors:Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J.
Deposit date:2006-01-03
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
1Z7D
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BU of 1z7d by Molmil
Ornithine aminotransferase PY00104 from Plasmodium Yoelii
Descriptor: ornithine aminotransferase
Authors:Walker, J.R, Alam, Z, Amani, M, Lew, J, Wasney, G, Boulanger, K, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
Deposit date:2005-03-24
Release date:2005-07-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2IW9
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BU of 2iw9 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MAGNESIUM ION, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-27
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
2IW6
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BU of 2iw6 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MAGNESIUM ION, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-26
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
6Q8E
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BU of 6q8e by Molmil
Crystal structure of branched-chain amino acid aminotransferase from Thermobaculum terrenum in PMP-form
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Branched-chain-amino-acid aminotransferase, CHLORIDE ION
Authors:Boyko, K.M, Bezsudnova, E.Y, Nikolaeva, A.Y, Zeifman, Y.S, Rakitina, T.V, Popov, V.O.
Deposit date:2018-12-14
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Biochemical and structural insights into PLP fold type IV transaminase from Thermobaculum terrenum.
Biochimie, 158, 2018
5HXX
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BU of 5hxx by Molmil
Crystal structure of AspAT from Corynebacterium glutamicum
Descriptor: 2-OXOGLUTARIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, ...
Authors:Son, H.-F, Kim, K.-J.
Deposit date:2016-01-31
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into a novel class of aspartate aminotransferase from Corynebacterium glutamicum
To be published
2IW8
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BU of 2iw8 by Molmil
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MONOTHIOGLYCEROL, ...
Authors:Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M.
Deposit date:2006-06-27
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
3IWV
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BU of 3iwv by Molmil
Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)
Descriptor: 5-hydroxyisourate hydrolase
Authors:Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G.
Deposit date:2009-09-03
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
3FFA
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BU of 3ffa by Molmil
Crystal Structure of a fast activating G protein mutant
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
Authors:Chauhan, R, Kapoor, N.
Deposit date:2008-12-02
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural evidence for a sequential release mechanism for activation of heterotrimeric g proteins.
J.Mol.Biol., 393, 2009
3IWU
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BU of 3iwu by Molmil
Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase
Descriptor: 5-hydroxyisourate hydrolase
Authors:Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G.
Deposit date:2009-09-03
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
3FRK
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BU of 3frk by Molmil
X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine
Descriptor: (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, QdtB
Authors:Thoden, J.B, Holden, H.M.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.
Biochemistry, 48, 2009
2I6F
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BU of 2i6f by Molmil
Receiver domain from Myxococcus xanthus social motility protein FrzS
Descriptor: CHLORIDE ION, Response regulator FrzS
Authors:Echols, N, Fraser, J, Merlie, J, Zusman, D, Alber, T.
Deposit date:2006-08-28
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Mol.Microbiol., 65, 2007
3FAT
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BU of 3fat by Molmil
X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ACETIC ACID, GLYCEROL, ...
Authors:Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S.
Deposit date:2008-11-18
Release date:2008-12-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
Febs Lett., 582, 2008
2YUE
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BU of 2yue by Molmil
Solution structure of the NEUZ (NHR) domain in Neuralized from Drosophila melanogaster
Descriptor: Protein neuralized
Authors:He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-06
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway.
J.Mol.Biol., 393, 2009
8WV6
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BU of 8wv6 by Molmil
PaaZ, bifunctional enzyme
Descriptor: Bifunctional protein PaaZ
Authors:Yadav, S, Vinothkumar, K.R.
Deposit date:2023-10-23
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024

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数据于2024-10-16公开中

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