3FRK
X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine
Summary for 3FRK
| Entry DOI | 10.2210/pdb3frk/pdb |
| Descriptor | QdtB, (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total) |
| Functional Keywords | aminotransferase, sugar-modification, natural porduct, transferase |
| Biological source | Thermoanaerobacterium thermosaccharolyticum (Thermoanaerobacterium thermosaccharolyticum) |
| Total number of polymer chains | 2 |
| Total formula weight | 86916.36 |
| Authors | Thoden, J.B.,Holden, H.M. (deposition date: 2009-01-08, release date: 2009-02-17, Last modification date: 2023-09-06) |
| Primary citation | Thoden, J.B.,Schaffer, C.,Messner, P.,Holden, H.M. Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose. Biochemistry, 48:1553-1561, 2009 Cited by PubMed: 19178182DOI: 10.1021/bi8022015 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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