3ILQ
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![BU of 3ilq by Molmil](/molmil-images/mine/3ilq) | Structure of mCD1d with bound glycolipid BbGL-2c from Borrelia burgdorferi | Descriptor: | (2S)-3-(alpha-D-galactopyranosyloxy)-2-(hexadecanoyloxy)propyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M. | Deposit date: | 2009-08-07 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells. Proc.Natl.Acad.Sci.USA, 107, 2010
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3ROO
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![BU of 3roo by Molmil](/molmil-images/mine/3roo) | Murine class I major histocompatibility complex H-2Kb in complex with immunodominant LCMV-derived gp34-41 peptide | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Madhurantakam, C, Duru, A.D, Leong, C, Sandalova, T, Webb, J.R, Achour, A. | Deposit date: | 2011-04-26 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition PLoS ONE, 2012
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6E7P
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![BU of 6e7p by Molmil](/molmil-images/mine/6e7p) | cryo-EM structure of human TRPML1 with PI35P2 | Descriptor: | (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1 | Authors: | Schmiege, P, Li, X. | Deposit date: | 2018-07-27 | Release date: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9, 2018
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2ZOL
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![BU of 2zol by Molmil](/molmil-images/mine/2zol) | Crystal structure of H-2Db in complex with the W513S variant of JHMV epitope S510 | Descriptor: | 9-meric peptide from Spike glycoprotein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Theodossis, A, Dunstone, M.A, Rossjohn, J. | Deposit date: | 2008-05-22 | Release date: | 2008-06-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biological basis of CTL escape in coronavirus-infected mice. J Immunol., 180, 2008
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6E7Y
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![BU of 6e7y by Molmil](/molmil-images/mine/6e7y) | cryo-EM structure of human TRPML1 with PI45P2 | Descriptor: | Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Schmiege, P, Li, X. | Deposit date: | 2018-07-27 | Release date: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9, 2018
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3ILP
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![BU of 3ilp by Molmil](/molmil-images/mine/3ilp) | Structure of mCD1d with bound glycolipid BbGL-2f from Borrelia burgdorferi | Descriptor: | (2S)-3-(alpha-D-galactopyranosyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl (9Z,12Z)-octadeca-9,12-dienoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M. | Deposit date: | 2009-08-07 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells. Proc.Natl.Acad.Sci.USA, 107, 2010
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4L8C
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![BU of 4l8c by Molmil](/molmil-images/mine/4l8c) | Crystal structure of the H2Db in complex with the NP-N3D peptide | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Rossjohn, J, Gras, S. | Deposit date: | 2013-06-16 | Release date: | 2013-10-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides. Nat Commun, 4, 2013
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3PQY
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![BU of 3pqy by Molmil](/molmil-images/mine/3pqy) | Crystal Structure of 6218 TCR in complex with the H2Db-PA224 | Descriptor: | 10-mer peptide from RNA-directed RNA polymerase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J. | Deposit date: | 2010-11-28 | Release date: | 2011-05-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.192 Å) | Cite: | Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses Proc.Natl.Acad.Sci.USA, 108, 2011
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3QUZ
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![BU of 3quz by Molmil](/molmil-images/mine/3quz) | Structure of the mouse CD1d-NU-alpha-GalCer-iNKT TCR complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-02-24 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
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3QZM
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![BU of 3qzm by Molmil](/molmil-images/mine/3qzm) | Staphylococcus aureus IsdA NEAT domain H83A variant in complex with heme | Descriptor: | GLYCEROL, Iron-regulated surface determinant protein A, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Grigg, J.C, Mao, C.X, Murphy, M.E.P. | Deposit date: | 2011-03-06 | Release date: | 2011-08-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Iron-Coordinating Tyrosine Is a Key Determinant of NEAT Domain Heme Transfer. J.Mol.Biol., 413, 2011
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3QUY
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![BU of 3quy by Molmil](/molmil-images/mine/3quy) | Structure of the mouse CD1d-BnNH-GSL-1'-iNKT TCR complex | Descriptor: | (2S,3R,4S,5R,6S)-6-[(2S,3S,4R)-2-(hexacosanoylamino)-3,4-dihydroxy-octadecoxy]-3,4,5-trihydroxy-N-(phenylmethyl)oxane-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-02-24 | Release date: | 2011-06-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
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3T1F
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![BU of 3t1f by Molmil](/molmil-images/mine/3t1f) | Crystal structure of the mouse CD1d-Glc-DAG-s2 complex | Descriptor: | (2S)-1-(alpha-D-glucopyranosyloxy)-3-(hexadecanoyloxy)propan-2-yl (11Z)-octadec-11-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Girardi, E, Zajonc, D.M. | Deposit date: | 2011-07-21 | Release date: | 2011-09-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat.Immunol., 12, 2011
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4MNG
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![BU of 4mng by Molmil](/molmil-images/mine/4mng) | Structure of the DP10.7 TCR with CD1d-sulfatide | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | Authors: | Luoma, A.M, Adams, E.J. | Deposit date: | 2013-09-10 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.0058 Å) | Cite: | Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity, 39, 2013
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3RTQ
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![BU of 3rtq by Molmil](/molmil-images/mine/3rtq) | Structure of the mouse CD1d-HS44-iNKT TCR complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-05-03 | Release date: | 2012-02-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. J.Immunol., 188, 2012
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4MQ7
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![BU of 4mq7 by Molmil](/molmil-images/mine/4mq7) | Structure of human CD1d-sulfatide | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | Authors: | Luoma, A.M, Adams, E.J. | Deposit date: | 2013-09-15 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6032 Å) | Cite: | Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity, 39, 2013
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3RUG
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![BU of 3rug by Molmil](/molmil-images/mine/3rug) | Crystal structure of Valpha10-Vbeta8.1 NKT TCR in complex with CD1d-alphaglucosylceramide (C20:2) | Descriptor: | (11E,14E)-N-[(2S,3S,4R)-1-(alpha-D-glucopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Patel, O, Rossjohn, J. | Deposit date: | 2011-05-05 | Release date: | 2011-08-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A semi-invariant V(alpha)10(+) T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties Nat.Immunol., 12, 2011
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3ARE
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![BU of 3are by Molmil](/molmil-images/mine/3are) | Ternary crystal structure of the mouse NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Wun, K.S, Rossjohn, J. | Deposit date: | 2010-11-27 | Release date: | 2011-03-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
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3ARF
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![BU of 3arf by Molmil](/molmil-images/mine/3arf) | Ternary crystal structure of the mouse NKT TCR-CD1d-C20:2 | Descriptor: | (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Wun, K.S, Rossjohn, J. | Deposit date: | 2010-11-27 | Release date: | 2011-03-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
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2YEZ
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![BU of 2yez by Molmil](/molmil-images/mine/2yez) | COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE | Descriptor: | 14-3-3 PROTEIN THETA, BETA-2-MICROGLOBULIN, MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21 | Authors: | Chappell, P, Roversi, P, Harrison, M.C, Mears, L.E, Kaufman, J.F, Lea, S.M. | Deposit date: | 2011-03-31 | Release date: | 2012-04-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding. Elife, 4, 2015
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3JVG
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![BU of 3jvg by Molmil](/molmil-images/mine/3jvg) | Crystal Structure of chicken CD1-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CHLORIDE ION, ... | Authors: | Dvir, H, Wang, J, Zajonc, D.M. | Deposit date: | 2009-09-16 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for lipid-antigen recognition in avian immunity. J.Immunol., 184, 2010
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4MX7
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![BU of 4mx7 by Molmil](/molmil-images/mine/4mx7) | Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl (9Z,9'Z)bis-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M, Wang, J. | Deposit date: | 2013-09-25 | Release date: | 2014-10-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | TBN To be Published
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3TBY
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![BU of 3tby by Molmil](/molmil-images/mine/3tby) | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F) | Descriptor: | Beta-2-microglobulin, GLYCOPROTEIN GPC, H-2 class I histocompatibility antigen, ... | Authors: | Duru, A.D, Allerbring, E.B, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A. | Deposit date: | 2011-08-08 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition To be Published
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3RZC
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![BU of 3rzc by Molmil](/molmil-images/mine/3rzc) | Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ... | Authors: | Yu, E.D, Girardi, E, Wang, J, Zajonc, D.M. | Deposit date: | 2011-05-11 | Release date: | 2011-08-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cutting Edge: Structural Basis for the Recognition of {beta}-Linked Glycolipid Antigens by Invariant NKT Cells. J.Immunol., 187, 2011
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3SCM
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![BU of 3scm by Molmil](/molmil-images/mine/3scm) | |
6BMK
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![BU of 6bmk by Molmil](/molmil-images/mine/6bmk) | Crystal structure of MHC-I like protein | Descriptor: | (2R)-1-(decanoyloxy)-3-(phosphonooxy)propan-2-yl octadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Khandokar, Y.B, Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-15 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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