5ZYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zyf by Molmil](/molmil-images/mine/5zyf) | Crystal structure of Streptococcus pyogenes type II-A Cas2 | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endoribonuclease Cas2, SULFATE ION | Authors: | Ka, D, Bae, E. | Deposit date: | 2018-05-24 | Release date: | 2018-08-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2 Nucleic Acids Res., 46, 2018
|
|
8IA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ia4 by Molmil](/molmil-images/mine/8ia4) | Crystal structure of Cas2 in complex with AcrVA5-peptide | Descriptor: | CRISPR-associated endoribonuclease Cas2, peptide | Authors: | Mo, X. | Deposit date: | 2023-02-07 | Release date: | 2023-03-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the inhibition of protospacer integration via direct interaction between Cas2 and AcrVA5. Nat Commun, 15, 2024
|
|
6JHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jhz by Molmil](/molmil-images/mine/6jhz) | Crystal structure of cas2 | Descriptor: | 5-mer peptide, CRISPR-associated endoribonuclease Cas2 | Authors: | Bi, M, Mo, X, Wang, C, Yuan, A.Y. | Deposit date: | 2019-02-19 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Structural insight into endonuclease CRISPR-associated Cas2 protein To be published
|
|
1ZPW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zpw by Molmil](/molmil-images/mine/1zpw) | |
3EXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3exc by Molmil](/molmil-images/mine/3exc) | Structure of the RNA'se SSO8090 from Sulfolobus solfataricus | Descriptor: | CHLORIDE ION, SODIUM ION, Uncharacterized protein | Authors: | Singer, A.U, Skarina, T, Tan, K, Kagan, O, Onopriyenko, O, Edwards, A.M, Joachimiak, A, Yakunin, A.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-10-16 | Release date: | 2008-11-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of the RNA'se SSO8090 from Sulfolobus solfataricus To be Published
|
|
3OQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oq2 by Molmil](/molmil-images/mine/3oq2) | Structure of a CRISPR associated protein Cas2 from Desulfovibrio vulgaris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CITRIC ACID, ... | Authors: | Samai, P, Smith, P, Shuman, S. | Deposit date: | 2010-09-02 | Release date: | 2010-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of a CRISPR-associated protein Cas2 from Desulfovibrio vulgaris. Acta Crystallogr.,Sect.F, 66, 2010
|
|
6ZI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zi1 by Molmil](/molmil-images/mine/6zi1) | Crystal structure of the isolated H. influenzae VapD toxin (D7N mutant) | Descriptor: | Endoribonuclease VapD | Authors: | Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E. | Deposit date: | 2020-06-24 | Release date: | 2020-10-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System. Structure, 29, 2021
|
|
6ZI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zi0 by Molmil](/molmil-images/mine/6zi0) | Crystal structure of the isolated H. influenzae VapD toxin (wildtype) | Descriptor: | Endoribonuclease VapD | Authors: | Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E. | Deposit date: | 2020-06-24 | Release date: | 2020-10-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System. Structure, 29, 2021
|
|
2IVY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ivy by Molmil](/molmil-images/mine/2ivy) | Crystal structure of hypothetical protein sso1404 from Sulfolobus solfataricus P2 | Descriptor: | HYPOTHETICAL PROTEIN SSO1404 | Authors: | Yan, X, Carter, L.G, Dorward, M, Liu, H, McMahon, S.A, Oke, M, Powers, H, White, M.F, Naismith, J.H. | Deposit date: | 2006-06-22 | Release date: | 2006-06-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
|
|
4ES3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4es3 by Molmil](/molmil-images/mine/4es3) | |
2I8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i8e by Molmil](/molmil-images/mine/2i8e) | Structure of SSO1404, a predicted DNA repair-associated protein from Sulfolobus solfataricus P2 | Descriptor: | Hypothetical protein, IODIDE ION | Authors: | Wang, S, Zimmerman, M.D, Kudritska, M, Chruszcz, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-01 | Release date: | 2006-09-26 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats. J.Biol.Chem., 283, 2008
|
|
5H1P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h1p by Molmil](/molmil-images/mine/5h1p) | CRISPR-associated protein | Descriptor: | ACETATE ION, CRISPR-associated endoribonuclease Cas2 | Authors: | Ka, D, Jeong, U, Bae, E. | Deposit date: | 2016-10-11 | Release date: | 2017-10-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity Struct Dyn, 4, 2017
|
|
5H1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h1o by Molmil](/molmil-images/mine/5h1o) | CRISPR-associated protein | Descriptor: | ACETATE ION, CRISPR-associated endoribonuclease Cas2 | Authors: | Ka, D, Jeong, U, Bae, E. | Deposit date: | 2016-10-11 | Release date: | 2017-10-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity Struct Dyn, 4, 2017
|
|
5G4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g4d by Molmil](/molmil-images/mine/5g4d) | |
4ES2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4es2 by Molmil](/molmil-images/mine/4es2) | |
4ES1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4es1 by Molmil](/molmil-images/mine/4es1) | |
2I0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i0x by Molmil](/molmil-images/mine/2i0x) | Hypothetical protein PF1117 from Pyrococcus furiosus | Descriptor: | Hypothetical protein PF1117 | Authors: | Chen, L.Q, Fu, Z.-Q, Liu, Z.-J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2006-08-11 | Release date: | 2006-10-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of Hypothetical Protein Pf1117 from Pyrococcus furiosus To be Published
|
|
4QR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qr0 by Molmil](/molmil-images/mine/4qr0) | Crystal structure of Streptococcus pyogenes Cas2 at pH 5.6 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
|
|
4QR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qr1 by Molmil](/molmil-images/mine/4qr1) | Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.193 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
|
|
4QR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qr2 by Molmil](/molmil-images/mine/4qr2) | Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
|
|
7F84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f84 by Molmil](/molmil-images/mine/7f84) | Crystal structure of CRISPR-associated Cas2c of Leptospira interrogans | Descriptor: | CRISPR-associated endoribonuclease Cas2, GLYCEROL | Authors: | Gogoi, P, Anand, V, Prabhakaran, H.S, Kumar, M, Kanaujia, S.P. | Deposit date: | 2021-07-01 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component. Front Mol Biosci, 9, 2022
|
|
4TNO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tno by Molmil](/molmil-images/mine/4tno) | Hypothetical protein PF1117 from Pyrococcus Furiosus: Structure solved by sulfur-SAD using Swiss Light Source Data | Descriptor: | CHLORIDE ION, CRISPR-associated endoribonuclease Cas2 | Authors: | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2014-06-04 | Release date: | 2014-12-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
|
|
6ZN8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zn8 by Molmil](/molmil-images/mine/6zn8) | Crystal structure of the H. influenzae VapXD toxin-antitoxin complex | Descriptor: | Endoribonuclease VapD, VapX | Authors: | Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E. | Deposit date: | 2020-07-06 | Release date: | 2020-11-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.211 Å) | Cite: | Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System. Structure, 29, 2021
|
|
3UI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ui3 by Molmil](/molmil-images/mine/3ui3) | |
7KFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kfu by Molmil](/molmil-images/mine/7kfu) | Cas6-RT-Cas1--Cas2 complex | Descriptor: | Cas2, Cas6-RT-Cas1 | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | Deposit date: | 2020-10-14 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nat Commun, 12, 2021
|
|