3W11
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3W13
| Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alphact peptide(693-719) and FAB 83-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | Authors: | Lawrence, M.C, Smith, B.J, Brzozowski, A.M. | Deposit date: | 2012-11-06 | Release date: | 2013-01-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.303 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
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3W12
| Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alpha-CT peptide(704-719) and FAB 83-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | Authors: | Lawrence, M.C, Smith, B.J, Brzozowsk, A.M. | Deposit date: | 2012-11-06 | Release date: | 2013-01-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.301 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
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5KQV
| Insulin receptor ectodomain construct comprising domains L1,CR,L2, FnIII-1 and alphaCT peptide in complex with bovine insulin and FAB 83-14 (REVISED STRUCTURE) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, Insulin receptor,Insulin receptor, ... | Authors: | Lawrence, M.C, Smith, B.J, Croll, T.I. | Deposit date: | 2016-07-06 | Release date: | 2017-07-19 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor. Nature, 493, 2013
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4XSS
| Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... | Authors: | Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C. | Deposit date: | 2015-01-22 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23, 2015
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