1N02
 
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2EZM
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3LHC
 | | Crystal structure of cyanovirin-n swapping domain b mutant | | Descriptor: | Cyanovirin-N, PHOSPHATE ION, SODIUM ION | | Authors: | Matei, E, Zheng, A, Furey, W, Rose, J, Aiken, C, Gronenborn, A.M. | | Deposit date: | 2010-01-21 | | Release date: | 2010-02-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization.
J.Biol.Chem., 285, 2010
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6X7H
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5K79
 | | Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog | | Descriptor: | 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER | | Authors: | Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M. | | Deposit date: | 2016-05-25 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure and Glycan Binding of a New Cyanovirin-N Homolog.
J.Biol.Chem., 291, 2016
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2EZN
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2RDK
 | | Five site mutated Cyanovirin-N with Mannose dimer bound | | Descriptor: | Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | Authors: | Fromme, R, Katiliene, Z, Fromme, P, Ghirlanda, G. | | Deposit date: | 2007-09-24 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution.
Protein Sci., 17, 2008
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2RP3
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3EZM
 | | CYANOVIRIN-N | | Descriptor: | PROTEIN (CYANOVIRIN-N) | | Authors: | Yang, F, Wlodawer, A. | | Deposit date: | 1998-12-15 | | Release date: | 1998-12-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping.
J.Mol.Biol., 288, 1999
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3CZZ
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3S3Z
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3S3Y
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2Y1S
 | | Microvirin lectin | | Descriptor: | Mannan-binding lectin | | Authors: | Bewley, C.A, Hussan, S. | | Deposit date: | 2010-12-10 | | Release date: | 2011-04-06 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
J. Biol. Chem., 286, 2011
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2YHH
 | | Microvirin:mannobiose complex | | Descriptor: | MANNAN-BINDING LECTIN, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | Authors: | Hussan, S, Bewley, C.A, Clore, G.M, Gustchina, E, Ghirlando, R. | | Deposit date: | 2011-05-02 | | Release date: | 2011-06-15 | | Last modified: | 2020-07-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Monovalent Lectin Microvirin in Complex with Man(Alpha)(1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity.
J.Biol.Chem., 286, 2011
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2Z21
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2L2F
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2PYS
 | | Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution | | Descriptor: | Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | | Authors: | Fromme, R, Katilene, Z, Fromme, P, Ghirlanda, G. | | Deposit date: | 2007-05-16 | | Release date: | 2007-07-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity.
Biochemistry, 46, 2007
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2JZJ
 | | Structure of CrCVNH (C. richardii CVNH) | | Descriptor: | Cyanovirin-N homolog | | Authors: | Koharudin, L.M.I, Viscomi, A.R, Jee, J, Ottonello, S, Gronenborn, A.M. | | Deposit date: | 2008-01-09 | | Release date: | 2008-03-25 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.
Structure, 16, 2008
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2JZL
 | | Structure of NcCVNH (N. CRASSA CVNH) | | Descriptor: | Cyanovirin-N homolog | | Authors: | Koharudin, L.M.I, Viscomi, A.R, Jee, J, Ottonello, S, Gronenborn, A.M. | | Deposit date: | 2008-01-09 | | Release date: | 2008-03-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.
Structure, 16, 2008
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2JZK
 | | Structure of TbCVNH (T. BORCHII CVNH) | | Descriptor: | Cyanovirin-N homolog | | Authors: | Koharudin, L.M.I, Viscomi, A.R, Jee, J, Ottonello, S, Gronenborn, A.M. | | Deposit date: | 2008-01-09 | | Release date: | 2008-03-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.
Structure, 16, 2008
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2KJL
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3GXY
 | | Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ... | | Authors: | Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A. | | Deposit date: | 2009-04-03 | | Release date: | 2009-05-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
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3GXZ
 | | Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9) | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ... | | Authors: | Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A. | | Deposit date: | 2009-04-03 | | Release date: | 2009-04-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
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4J4G
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4J4E
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