1B3U
| CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA | Descriptor: | PROTEIN (PROTEIN PHOSPHATASE PP2A) | Authors: | Groves, M.R, Hanlon, N, Turowski, P, Hemmings, B, Barford, D. | Deposit date: | 1998-12-14 | Release date: | 1999-04-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell(Cambridge,Mass.), 96, 1999
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1QBK
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2BKU
| Kap95p:RanGTP complex | Descriptor: | GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ... | Authors: | Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M. | Deposit date: | 2005-02-21 | Release date: | 2005-05-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis for Nuclear Import Complex Dissociation by Rangtp Nature, 435, 2005
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2DB0
| Crystal structure of PH0542 | Descriptor: | 253aa long hypothetical protein | Authors: | Nishino, A, Handa, N, Kishishita, S, Murayama, K, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-14 | Release date: | 2006-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of PH0542 To be Published
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2H4M
| Karyopherin Beta2/Transportin-M9NLS | Descriptor: | Heterogeneous nuclear ribonucleoprotein A1, Transportin-1 | Authors: | Chook, Y.M, Cansizoglu, A.E. | Deposit date: | 2006-05-24 | Release date: | 2006-10-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Rules for nuclear localization sequence recognition by karyopherin beta 2. Cell(Cambridge,Mass.), 126, 2006
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2IAE
| Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | Authors: | Cho, U.S, Xu, W. | Deposit date: | 2006-09-07 | Release date: | 2006-12-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme. Nature, 445, 2007
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2IE3
| Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins | Descriptor: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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2IE4
| Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid | Descriptor: | MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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2NPP
| Structure of the Protein Phosphatase 2A Holoenzyme | Descriptor: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | Authors: | Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y. | Deposit date: | 2006-10-28 | Release date: | 2006-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the protein phosphatase 2A holoenzyme Cell(Cambridge,Mass.), 127, 2006
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2NYL
| Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated | Descriptor: | MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y. | Deposit date: | 2006-11-20 | Release date: | 2006-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
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2NYM
| Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit | Descriptor: | MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... | Authors: | Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y. | Deposit date: | 2006-11-21 | Release date: | 2006-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
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2OT8
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2PF4
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2PKG
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2QMR
| Karyopherin beta2/transportin | Descriptor: | Transportin-1 | Authors: | Cansizoglu, A.E, Chook, Y.M. | Deposit date: | 2007-07-16 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Conformational heterogeneity of karyopherin beta2 is segmental Structure, 15, 2007
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2Z5J
| Free Transportin 1 | Descriptor: | Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | Deposit date: | 2007-07-13 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
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2Z5K
| Complex of Transportin 1 with TAP NLS | Descriptor: | Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M. | Deposit date: | 2007-07-14 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
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2Z5M
| Complex of Transportin 1 with TAP NLS, crystal form 2 | Descriptor: | Nuclear RNA export factor 1, Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | Deposit date: | 2007-07-14 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
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2Z5N
| Complex of Transportin 1 with hnRNP D NLS | Descriptor: | Heterogeneous nuclear ribonucleoprotein D0, Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | Deposit date: | 2007-07-14 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
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2Z5O
| Complex of Transportin 1 with JKTBP NLS | Descriptor: | Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1 | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | Deposit date: | 2007-07-14 | Release date: | 2007-10-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
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3C5W
| Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | Descriptor: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | Deposit date: | 2008-02-01 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
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3DW8
| Structure of a Protein Phosphatase 2A Holoenzyme with B55 subunit | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | Authors: | Xu, Y, Chen, Y, Zhang, P, Jeffrey, P.D, Shi, Y. | Deposit date: | 2008-07-21 | Release date: | 2008-10-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation. Mol.Cell, 31, 2008
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3EA5
| Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... | Authors: | Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. | Deposit date: | 2008-08-24 | Release date: | 2008-10-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008
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3FGA
| Structural Basis of PP2A and Sgo interaction | Descriptor: | MANGANESE (II) ION, MICROCYSTIN-LR, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... | Authors: | Xu, Z, Xu, W. | Deposit date: | 2008-12-05 | Release date: | 2009-09-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and function of the PP2A-shugoshin interaction Mol.Cell, 35, 2009
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3K7V
| Protein phosphatase 2A core complex bound to dinophysistoxin-1 | Descriptor: | (2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-6'-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-1-hydroxybutyl}-8'-hydroxy-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Jeffrey, P.D, Huhn, J, Shi, Y. | Deposit date: | 2009-10-13 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A structural basis for the reduced toxicity of dinophysistoxin-2. Chem.Res.Toxicol., 22, 2009
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