PDB: 19040 resultsInfo pagesStatus searchChemie searchBIRD

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1B62	MUTL COMPLEXED WITH ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (MUTL) Authors: Wei, Y. Deposit date: 1999-01-11 Release date: 1999-04-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell(Cambridge,Mass.), 97, 1999
6ETS	Crystal structure of KDM4D with tetrazolhydrazide compound 1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... Authors: Malecki, P.H, Link, A, Weiss, M.S, Heinemann, U. Deposit date: 2017-10-27 Release date: 2019-02-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.333 Å) Cite: Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases. Chemmedchem, 14, 2019
5X1U	Structure of the cytosolic domain of DotM derived from Legionella pneumophila Descriptor: Uncharacterized protein Authors: Kwak, M.J, Kim, Y.G, Oh, B.H. Deposit date: 2017-01-26 Release date: 2017-06-14 Last modified: 2018-06-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Architecture of the type IV coupling protein complex of Legionella pneumophila Nat Microbiol, 2, 2017
1AI3	ORBITAL STEERING IN THE CATALYTIC POWER OF ENZYMES: SMALL STRUCTURAL CHANGES WITH LARGE CATALYTIC CONSEQUENCES Descriptor: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION, ... Authors: Stoddard, B.L, Mesecar, A, Koshland Junior, D.E. Deposit date: 1997-04-30 Release date: 1997-11-12 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences. Science, 277, 1997
1ZXV	X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid. Descriptor: (E)-3-(5((5-(4-CHLOROPHENYL)FURAN-2-YL)METHYLENE)-4-OXO-2-THIOXOTHIAZOLIDIN-3-YL)PROPANOIC ACID, ZINC ION, lethal factor Authors: Wong, T.Y, Liddington, R.C. Deposit date: 2005-06-08 Release date: 2005-07-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Efficient synthetic inhibitors of anthrax lethal factor. Proc.Natl.Acad.Sci.Usa, 102, 2005
1QKN	RAT OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH ANTAGONIST RALOXIFENE Descriptor: ACETATE ION, ESTROGEN RECEPTOR BETA, RALOXIFENE Authors: Pike, A.C.W, Brzozowski, A.M, Carlquist, M. Deposit date: 1999-07-27 Release date: 2000-07-28 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist Embo J., 18, 1999
5X1H	Structure of Legionella pneumophila DotN Descriptor: IcmJ (DotN), ZINC ION Authors: Kwak, M.J, Oh, B.H. Deposit date: 2017-01-26 Release date: 2017-06-14 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.005 Å) Cite: Architecture of the type IV coupling protein complex of Legionella pneumophila Nat Microbiol, 2, 2017
1QKM	HUMAN OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PARTIAL AGONIST GENISTEIN Descriptor: ESTROGEN RECEPTOR BETA, GENISTEIN Authors: Pike, A.C.W, Brzozowski, A.M, Carlquist, M. Deposit date: 1999-07-27 Release date: 2000-07-28 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist Embo J., 18, 1999
5KSI	Crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-Bisphosphoglycerate Descriptor: (2R)-2,3-diphosphoglyceric acid, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, ... Authors: Ahmed, M.H, Safo, M.K, Xia, Y. Deposit date: 2016-07-08 Release date: 2017-07-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep, 7, 2017
8EKF	X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3 Descriptor: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3 Authors: Moskovitz, R, Wilson, I.A. Deposit date: 2022-09-20 Release date: 2022-10-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nat Commun, 14, 2023
5L3V	Structure of the crenarchaeal SRP54 GTPase bound to GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle 54 kDa protein Authors: Bange, G, Wild, K, Sinning, I. Deposit date: 2016-05-24 Release date: 2016-06-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
5L3S	Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Bange, G, Wild, K, Sinning, I. Deposit date: 2016-05-24 Release date: 2016-06-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
6AHC	Cryo-EM structure of aldehyde-alcohol dehydrogenase reveals a high-order helical architecture critical for its activity Descriptor: Aldehyde-alcohol dehydrogenase Authors: Kim, G, Song, J.J. Deposit date: 2018-08-17 Release date: 2019-08-21 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity. Nat Commun, 10, 2019
6V7A	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2657 Descriptor: Hdac6 protein, N-hydroxy-4-[(1-methyl-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)methyl]benzamide, POTASSIUM ION, ... Authors: Osko, J.D, Christianson, D.W. Deposit date: 2019-12-08 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.0874176 Å) Cite: Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation. Acs Med.Chem.Lett., 11, 2020
6ETT	Crystal structure of KDM4D with tetrazole compound 4 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... Authors: Malecki, P.H, Link, A, Weiss, M.S, Heinemann, U. Deposit date: 2017-10-27 Release date: 2019-02-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.257 Å) Cite: Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases. Chemmedchem, 14, 2019
6UP0	Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin Descriptor: MAGNESIUM ION, Mango-III fluorescent aptamer, POTASSIUM ION, ... Authors: Trachman, R.J, Ferre-D'Amare, A.R. Deposit date: 2019-10-16 Release date: 2020-10-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET. Rna, 27, 2021
5JJR	Dengue 3 NS5 protein with compound 29 Descriptor: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ... Authors: Lescar, J, El Sahili, A. Deposit date: 2016-04-25 Release date: 2016-07-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Plos Pathog., 12, 2016
5JJS	Dengue 3 NS5 protein with compound 27 Descriptor: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-{[(1R,3R)-3-methoxycyclohexyl]sulfonyl}benzamide, DI(HYDROXYETHYL)ETHER, ... Authors: Lescar, J, El Sahili, A. Deposit date: 2016-04-25 Release date: 2016-07-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Plos Pathog., 12, 2016
6ETV	Crystal structure of KDM4D with tetrazolhydrazide compound 2 Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Malecki, P.H, Link, A, Weiss, M.S, Heinemann, U. Deposit date: 2017-10-27 Release date: 2019-02-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases. Chemmedchem, 14, 2019
1ZIL	GCN4-LEUCINE ZIPPER CORE MUTANT ASN16GLN IN THE DIMERIC STATE Descriptor: GENERAL CONTROL PROTEIN GCN4 Authors: Gonzalez Junior, L, Woolfson, D.N, Alber, T. Deposit date: 1996-10-30 Release date: 1997-07-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Buried polar residues and structural specificity in the GCN4 leucine zipper. Nat.Struct.Biol., 3, 1996
1ZIM	GCN4-LEUCINE ZIPPER CORE MUTANT ASN16GLN IN THE TRIMERIC STATE Descriptor: GENERAL CONTROL PROTEIN GCN4 Authors: Gonzalez Junior, L, Woolfson, D.N, Alber, T. Deposit date: 1996-10-30 Release date: 1997-07-07 Last modified: 2021-11-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Buried polar residues and structural specificity in the GCN4 leucine zipper. Nat.Struct.Biol., 3, 1996
1ZIK	GCN4-LEUCINE ZIPPER CORE MUTANT ASN16LYS IN THE DIMERIC STATE Descriptor: GENERAL CONTROL PROTEIN GCN4 Authors: Gonzalez Junior, L, Woolfson, D.N, Alber, T. Deposit date: 1996-10-30 Release date: 1997-07-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Buried polar residues and structural specificity in the GCN4 leucine zipper. Nat.Struct.Biol., 3, 1996
6V79	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2376 Descriptor: 1,2-ETHANEDIOL, 4-{[(2S)-3,3-dimethyl-2-(pyridin-3-yl)-2,3-dihydro-1H-indol-1-yl]methyl}-N-hydroxybenzamide, Hdac6 protein, ... Authors: Osko, J.D, Christianson, D.W. Deposit date: 2019-12-08 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.03951526 Å) Cite: Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors. J.Med.Chem., 64, 2021
5XBK	Crystal structure of human Importin4 Descriptor: Importin-4, histone H3 Authors: Song, J.J, Yoon, J. Deposit date: 2017-03-20 Release date: 2018-02-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.223 Å) Cite: Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding J. Mol. Biol., 430, 2018
5XD0	Apo Structure of Beta-1,3-1,4-glucanase from Paenibacillus sp.X4 Descriptor: DI(HYDROXYETHYL)ETHER, Glucanase, TRIETHYLENE GLYCOL Authors: Baek, S.C, Ho, T.-H, Kang, L.-W, Kim, H. Deposit date: 2017-03-24 Release date: 2017-04-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Improvement of enzyme activity of beta-1,3-1,4-glucanase from Paenibacillus sp. X4 by error-prone PCR and structural insights of mutated residues. Appl. Microbiol. Biotechnol., 101, 2017

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