PDB: 22634 resultsInfo pagesStatus searchChemie searchBIRD

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2HW2	Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin Descriptor: GLYCINE, RIFAMPICIN, Rifampin ADP-ribosyl transferase Authors: Baysarowich, J, Wright, G.D, Junop, M. Deposit date: 2006-07-31 Release date: 2007-07-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr. Proc.Natl.Acad.Sci.Usa, 105, 2008
4NXI	Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein Authors: Albesa-Jove, D, Urresti, S, Comino, N, Guerin, M.E. Deposit date: 2013-12-09 Release date: 2014-10-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
2OZ5	Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS Descriptor: Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID Authors: Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC) Deposit date: 2007-02-23 Release date: 2007-05-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB. Structure, 15, 2007
2FP2	Secreted Chorismate Mutase from Mycobacterium tuberculosis Descriptor: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Chorismate mutase Authors: Okvist, M, Dey, R, Sasso, S, Grahn, E, Kast, P, Krengel, U. Deposit date: 2006-01-15 Release date: 2006-03-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.64 Å) Cite: 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed J.Mol.Biol., 357, 2006
3X3M	Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121 Descriptor: CALCIUM ION, ESX-1 secretion system protein EccB1 Authors: Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. Deposit date: 2015-01-24 Release date: 2015-12-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase. Faseb J., 29, 2015
2XTA	Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase in complex with acetyl-CoA (triclinic form) Descriptor: 2-OXOGLUTARATE DECARBOXYLASE, ACETYL COENZYME *A, CALCIUM ION, ... Authors: Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M. Deposit date: 2010-10-05 Release date: 2011-06-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism. Chem.Biol., 18, 2011
1XSF	Solution structure of a resuscitation promoting factor domain from Mycobacterium tuberculosis Descriptor: Probable resuscitation-promoting factor rpfB Authors: Cohen-Gonsaud, M, Barthe, P, Henderson, B, Ward, J, Roumestand, C, Keep, N.H. Deposit date: 2004-10-19 Release date: 2005-02-15 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes Nat.Struct.Mol.Biol., 12, 2005
1XXU	Crystal Structure of AhpE from Mycrobacterium tuberculosis, a 1-Cys peroxiredoxin Descriptor: Hypothetical protein Rv2238c/MT2298 Authors: Li, S, Peterson, N.A, Kim, M.Y, Kim, C.Y, Hung, L.W, Yu, M, Lekin, T, Segelke, B.W, Lott, J.S, Baker, E.N, TB Structural Genomics Consortium (TBSGC) Deposit date: 2004-11-08 Release date: 2005-02-22 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin J.Mol.Biol., 346, 2005
4DQV	Crystal structure of reductase (R) domain of non-ribosomal peptide synthetase from Mycobacterium tuberculosis Descriptor: PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) Authors: Haque, A.S, Panjikar, S, Sankaranarayanan, R. Deposit date: 2012-02-16 Release date: 2012-06-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc.Natl.Acad.Sci.USA, 109, 2012
1Y3I	Crystal Structure of Mycobacterium tuberculosis NAD kinase-NAD complex Descriptor: GLYCEROL, Inorganic polyphosphate/ATP-NAD kinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Mori, S, Yamasaki, M, Maruyama, Y, Momma, K, Kawai, S, Hashimoto, W, Mikami, B, Murata, K. Deposit date: 2004-11-25 Release date: 2005-01-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase-NAD complex Biochem.Biophys.Res.Commun., 327, 2005
2FP1	Secreted Chorismate Mutase from Mycobacterium tuberculosis Descriptor: Chorismate mutase, LEAD (II) ION Authors: Okvist, M, Dey, R, Sasso, S, Grahn, E, Kast, P, Krengel, U. Deposit date: 2006-01-15 Release date: 2006-03-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed J.Mol.Biol., 357, 2006
7YY9	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 13 Descriptor: 2-azanyl-4-chloranyl-benzenecarbonitrile, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.485 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YYB	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 15 Descriptor: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.751 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY6	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 10 Descriptor: 6-methylpyridine-2,3-dicarboxylic acid, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.506 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY3	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 7 Descriptor: 5-fluoroindole-2-carboxylic acid, MAGNESIUM ION, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.535 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YWM	Crystal structure of Mycobacterium abcessus Phosphopantetheine adenylyltransferase in complex with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-14 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.624 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YYC	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 16 Descriptor: 2-indol-1-ylethanoic acid, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.499 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY7	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 11 Descriptor: 3-hydroxynaphthalene-2-carboxylic acid, Phosphopantetheine adenylyltransferase, SULFATE ION Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.538 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY2	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Compound 20 Descriptor: 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.598 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY8	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 12 Descriptor: (2R)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid, 3-(INDOL-3-YL) LACTATE, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.516 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY4	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 8 Descriptor: 6-fluoranylnaphthalene-2-carboxylic acid, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.671 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YYA	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 14 Descriptor: 3-indol-1-ylpropanoic acid, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-06-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.807 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
3FSX	Structure of tetrahydrodipicolinate N-succinyltransferase (Rv1201c; DapD) from Mycobacterium tuberculosis Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, MAGNESIUM ION, ... Authors: Schuldt, L, Weyand, S, Kefala, G, Weiss, M.S. Deposit date: 2009-01-12 Release date: 2009-06-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism. J.Mol.Biol., 389, 2009
7YXZ	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Coenzyme A Descriptor: COENZYME A, Phosphopantetheine adenylyltransferase Authors: Thomas, S.E, Coyne, A.G, Blundell, T.L. Deposit date: 2022-02-17 Release date: 2022-07-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.779 Å) Cite: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
1YS6	Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis Descriptor: CALCIUM ION, GLYCEROL, Transcriptional regulatory protein prrA Authors: Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) Deposit date: 2005-02-07 Release date: 2006-02-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis To be published

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